A practical preparation guide
Instructions for authors
These instructions identify the information needed to assess biotechnology and biomedical science manuscripts consistently. Authors should confirm scope, prepare the manuscript and declarations below, and then choose one of the approved routes listed on the Submit Paper page.
Submission essentials
- Article types: Research, Review and Short Communication.
- Review: single-blind; double-blind may be requested.
- A cover letter and manuscript file are required.
- Use only one approved submission route for the manuscript.
On this page
Article types
JBBS accepts three article types. Select the corresponding type when submitting.
| Portal category | Purpose and expected structure |
|---|---|
| Research | An original experimental, observational, computational or methods-based study with a defined question, reproducible methods, results and interpretation. |
| Review | A critical synthesis of a defined biotechnology or biomedical science question. Systematic or scoping reviews should report the search, selection and synthesis method and use the appropriate reporting guideline. |
| Short Communication | A concise report of a complete, clearly supported result that does not require a full Research Article format. |
Prepare a complete, reproducible account appropriate to the article type. Before final upload, follow any current word, reference, figure, table and file limits displayed by the selected submission route.
Manuscript organization
Include a title page; abstract and keywords; main text appropriate to the article type; acknowledgments; author contributions; funding and competing-interest declarations; a data and materials availability statement; references; figure legends; tables; and supplementary files where needed.
- Research manuscripts should use Introduction, Materials and methods, Results, Discussion and Conclusions unless the design requires a recognized alternative.
- Reviews should state their evidence-selection and synthesis method. Short Communications must retain enough methodological detail for evaluation and repetition.
- Give every author’s full name, institutional affiliation and email address, identify the corresponding author, and add an ORCID iD where available.
- Use precise scientific nomenclature, define abbreviations at first use and identify organisms, genes, proteins, materials and software consistently.
Methods and reproducibility
Describe the study design, biological system, sampling or experimental units, inclusion and exclusion criteria, controls, independent replicates, randomization and blinding where applicable, instruments, software and versions, statistical methods, and any protocol deviation. Identify materials precisely enough for another group to obtain or reproduce them.
Microbial and bioprocess work
Identify organisms or strains, culture conditions, medium, reactor or fermentation conditions, containment and key process parameters.
Natural-product and plant work
Give taxonomic identification, voucher information where available, source and collection details, extraction and analytical methods.
Biomaterials and tissue engineering
Report material composition, fabrication, characterization, biological model, controls and mechanical or biological test conditions.
Molecular diagnostics and gene expression
Report specimen handling, assay platform, controls, normalization, primer, probe or target information, decision thresholds and validation method.
Human, animal and biosafety requirements
- Human research must state the approving ethics body, approval identifier and informed-consent process. Interventional clinical trials must be registered prospectively in an accepted public registry at or before the first participant provides consent for enrollment; report the registry name, registration number and registration date. Minimize identifiers and obtain consent for identifiable information or images.
- Animal studies must state approval by the responsible animal-care body or equivalent, applicable national requirements and welfare protections. Use ARRIVE reporting where it applies.
- Work involving pathogens, recombinant or genetically modified organisms, hazardous biological material or dual-use concerns must state the relevant biosafety approval, containment level and risk controls.
- A manuscript lacking approval or consent required for its study cannot proceed on scientific merit alone.
Data, code and biological materials
Every Research Article must contain a data-availability statement. Cite the repository and accession or persistent identifier when data are deposited. For restricted human data, describe the lawful access route and reason for restriction. Computational work should provide code, parameters and environment information sufficient to reproduce the analysis, or explain a justified restriction.
Report the source and identifier of each cell line, the authentication method and date, and contamination testing where relevant. Give persistent identifiers or catalog numbers for critical antibodies, reagents, strains, plasmids and constructs where available. State how unique materials or protocols can be requested.
Figures, images, tables and statistics
Number every figure and table in the order cited. Legends must identify biological material, conditions, sample size, statistical test and the meaning of error bars or symbols where applicable. Image adjustment must be applied consistently and must not obscure, remove or create data. Retain uncropped source images and underlying measurements.
Report the sample-size rationale; effect estimates with confidence intervals where appropriate; exact P values where appropriate; handling of multiple comparisons and missing data; the experimental unit; technical and biological replicates; and the statistical software and version used.
Reporting, authorship and AI tools
Use the reporting guideline appropriate to the study design and include a checklist when required. Examples include ARRIVE for animal research, PRISMA for systematic reviews, STROBE for observational studies, CONSORT for trials, STARD for diagnostic-accuracy studies and MIQE for quantitative PCR.
All listed authors must have made an accountable contribution, approve the submitted version and agree to its submission. Identify author contributions, all funding sources and the funder’s role, and disclose financial, professional, personal and intellectual-property interests.
Generative AI tools cannot be authors. Authors remain responsible for accuracy, attribution, confidentiality and originality and must disclose permitted use that affected text, code, images or analysis. Do not upload confidential manuscript, participant or peer-review material to an unauthorized AI service.
Files, submission, revision and publication
A cover letter and at least one manuscript file are required. The submission system displays its current accepted manuscript, figure, supplementary-file formats, resolution requirements and size limits at upload. Enter the title, abstract, keywords and article type in the selected route even when they appear in the manuscript. Use one submission record and upload revisions to that record rather than opening a second submission or changing routes.
ManuscriptZone is the primary route. Authors may instead use the simple manuscript submission form or, where permitted by the editorial office, submit by editorial email. The Submit Paper page explains the route hierarchy. Use only one route for the same manuscript.
If revision is invited, provide a point-by-point response and identify where each change was made. A revision invitation is not an acceptance decision. After acceptance, review production proofs for accuracy; substantive changes require editorial approval. Report a material post-publication error to the editorial office so the appropriate correction process can be considered.
Ready to use the submission checklist?
The Submit Paper page explains the primary, alternative and assisted routes. Use only one route for the same manuscript.
Read the Aims & Scope, Editorial Policies and APC information before opening a new submission.