Overview
Chorionic villus sampling (CVS) is a prenatal diagnostic procedure used to detect chromosomal and certain genetic disorders in a developing fetus. It involves taking a small sample of chorionic villi, the tiny finger-like projections of placental tissue that share the fetus's genetic makeup. The sample is obtained either through the cervix or through the abdominal wall under ultrasound guidance, and the cells are analyzed for chromosomal abnormalities such as Down syndrome and for specific inherited conditions when there is a known familial risk. CVS is typically performed earlier in pregnancy than amniocentesis, usually between about 10 and 13 weeks, which allows results to be available sooner. Like other invasive prenatal tests, it carries a small risk of miscarriage and is generally offered when the potential benefit of early diagnosis is significant, such as advanced maternal age or a positive screening result. Women's Reproductive Health, the OpenAccessPub journal hosting this page, publishes peer-reviewed, open-access research on reproductive and perinatal health, including the diagnosis and management of inherited and genetic conditions. This page gathers open-access scholarship relevant to chorionic villus sampling and prenatal genetic diagnosis.
Research published in this journal
2 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Toward Better Care for Sickle Cell Disease in Nigeria: A Review of Challenges and Interventions
How this research is being cited
The 2 articles above have been cited 1 time in the scholarly literature. Citation data via OpenAlex and Crossref, updated Oct 2025.
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2024 · medRxiv (Cold Spring Harbor Laboratory)
A sample of recent works citing this journal's research on Chorionic Villus Sampling, linking to each citing work.