Research Topic · Peer-Reviewed

Insulin

Insulin is the peptide hormone secreted by the beta cells of the pancreatic islets that lowers blood glucose by promoting its uptake into muscle and adipose tissue, stimulating glycogen synthesis in liver and muscle, and inhibiting gluconeogenesis and lipolysis. Acting through the insulin receptor and downstream sig…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 36× across the literature 🔖 ISSN 2578-2371 🗓 Reviewed July 2026

Overview

Insulin is the peptide hormone secreted by the beta cells of the pancreatic islets that lowers blood glucose by promoting its uptake into muscle and adipose tissue, stimulating glycogen synthesis in liver and muscle, and inhibiting gluconeogenesis and lipolysis. Acting through the insulin receptor and downstream signalling cascades, it is the principal anabolic regulator of carbohydrate, lipid, and protein metabolism, and its deficiency or the failure of target tissues to respond produces the hyperglycaemia of diabetes mellitus. Insulin is central to the pathophysiology and treatment of diabetes and is closely linked to obesity, metabolic syndrome, and reproductive and hepatic metabolic disorders. The peer-reviewed work assembled here engages these dimensions: the stability of insulin in cell-culture media, identification of insulin-sensitive versus insulin-resistant phenotypes in postmenopausal women, the interplay of glucose and insulin in regulating matrix metalloproteinase, cinnamon supplementation and insulin resistance in polycystic ovary syndrome, development of non-invasive glucose-monitoring approaches, the impact of nutrients on diabetes, and metabolomic profiling in type 2 diabetes. Across these studies insulin appears through its signalling and sensitivity, its role in glucose regulation and metabolic disease, and the dietary and technological strategies aimed at its assessment and management. The collection situates insulin as a key metabolic hormone whose action and dysregulation underlie diabetes, insulin resistance, and associated metabolic and hepatic disorders.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2014

Bioinformatics of Metabolomics in Diabetes Mellitus Type 2

Ahmad Sliem HamdyCorresponding author
Biochemistry and internal Medicine*, Basic oral and medical sciences, College of dentistry, Qassim University, Saudi Arabia
Exact topic Bioinformatics And Diabetes Cited by 2 doi:10.14302/issn.2374-9431.jbd-13-212

How this research is being cited

The 12 articles above have been cited 36 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Insulin, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Spleen And Liver Research (ISSN 2578-2371).

Journal editorial board
Florin Graur · Romania

This page summarises published research for orientation; it is not medical or professional advice.