Hepatitis B is liver inflammation caused by the hepatitis B virus (HBV), a partially double-stranded DNA virus of the family Hepadnaviridae that replicates in hepatocytes through a reverse-transcribed pregenomic RNA intermediate and persists as covalently closed circular DNA. Transmission is parenteral, perinatal an…
Hepatitis B is liver inflammation caused by the hepatitis B virus (HBV), a partially double-stranded DNA virus of the family Hepadnaviridae that replicates in hepatocytes through a reverse-transcribed pregenomic RNA intermediate and persists as covalently closed circular DNA. Transmission is parenteral, perinatal and sexual, through blood and body fluids, and the natural history depends strongly on age at infection: neonatal acquisition usually becomes chronic, whereas most adult infections resolve. Chronic hepatitis B is staged using HBsAg, HBeAg, anti-HBe and HBV DNA quantification together with aminotransferases and fibrosis assessment, and it carries substantial risk of cirrhosis and hepatocellular carcinoma. Nucleos(t)ide analogues such as tenofovir and entecavir suppress viral replication, while a recombinant surface-antigen vaccine provides durable prevention. Work in this area includes tenofovir treatment of chronic hepatitis B in a teaching-hospital cohort, the burden and trends of chronic liver disease, occupational knowledge and prevention practices among hospital cleaners, confirmatory diagnostic testing in blood donors, screening and misconceptions around blood donation, and angiogenic markers in HCV-related hepatocellular carcinoma that frame shared mechanisms of viral hepatocarcinogenesis. The journal publishes peer-reviewed clinical, virological and public-health research on hepatitis B infection, prevention and treatment.
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 12 articles above have been cited 59 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Hepatitis b, linking to each citing work.