Overview
Stiffness is a measure of how much a material or tissue resists deformation when a force is applied to it. A stiffer structure changes shape less under load, while a more compliant one deforms more readily. In biology and medicine, stiffness is an important property at many scales: the stiffness of muscles and tendons influences how force and movement are produced, the stiffness of the matrix that surrounds cells affects how those cells behave, and the stiffness of organs such as the liver can reflect underlying disease. Measuring stiffness therefore provides insight into both normal function and pathology. Research collected on this journal spans these dimensions of stiffness. Work includes the mechanical properties and musculo-tendinous stiffness of human muscle, the influence of substrate stiffness on protein expression in retinal cells, and the assessment of liver stiffness in relation to chronic liver disease. Together these contributions illustrate how stiffness is quantified and how it relates to tissue structure and function. As a property central to the mechanics of muscle, tendon, and other tissues, stiffness falls within the scope of Skeletal Muscle and biomechanics research. The page gathers peer-reviewed, open-access research relevant to tissue and musculoskeletal stiffness.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Substrate Stiffness Influences the Time Dependence of CTGF Protein Expression in Müller Cells
Liver Stiffness by ARFI does not Correlate with Decompensation and Portal Hypertension in Patients with Cirrhosis
Impact of Low Birth Weight on Early Vascular Aging and Cardiometabolic Phenotypes in Later Life Among Cameroonian Adults
Endothelial Function in Stroke Subtypes Using Endopat Technology
A Meningeal Syndrome Revealing A Tetanus in A Togolese: Case Report and Review of the Literature
Elasticity Profile of Skin, Neuronal, Cardiac, and Skeletal Muscle Cells after Treatment with the Biofield Energy Healing-Based Proprietary Test Formulation
Metabolic Acidosis and Cardiovascular Disease in Patients on Peritoneal Dialysis
The NH2-Terminal Ig Domains of Insect Projectin could serve as Elastic Elements
Cardiorenal Signaling Pathways in Heart Failure: Good and Bad News
The Lower Prevalence of Chronic Diseases Risk Factors in Vegetarian Brazilians Subjects – CARVOS Study
How this research is being cited
The 12 articles above have been cited 44 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Frontiers in Immunology
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2025 · Experimental Physiology
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2025 · Human Physiology
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2025 · Human Physiology
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2025 · Experimental Physiology
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2025 · ACS Nano
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2025 · Neuroscience Bulletin
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2025 · ACS Nano
A sample of recent works citing this journal's research on Stiffness, linking to each citing work.