Research Topic · Peer-Reviewed

Quantitative Proteomics

Quantitative proteomics is a set of methods in molecular biology that measure the abundance of proteins within a biological sample, enabling researchers to detect and quantify changes in protein levels across different conditions. It commonly relies on mass spectrometry, often combined with labelling strategies such…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 78× across the literature 🔖 ISSN 2326-0793 🗓 Reviewed July 2026

Overview

Quantitative proteomics is a set of methods in molecular biology that measure the abundance of proteins within a biological sample, enabling researchers to detect and quantify changes in protein levels across different conditions. It commonly relies on mass spectrometry, often combined with labelling strategies such as stable isotope labelling, and provides a system-wide view of protein expression for research and diagnostic applications. The field is important because proteins are the principal effectors of cellular function, and quantifying them reveals how biological systems respond to disease, treatment, and environmental change in ways not always evident from gene expression alone. Research published under this topic includes quantitative approaches using 15N SILAC mouse models and ion-current-based strategies for assessing the proteomic response to drug treatment such as lapatinib. Methodological and conceptual articles address discovery and quantification in mass spectrometry-based proteomics, the scope of the Human Proteome Project, and bioinformatics for disease diagnosis and treatment. Applied studies examine proteomic responses in cereal crops under drought and salt stress, alveolar macrophage proteomes in transgenic mice, and bioinformatic analysis of disease-associated proteins in atherosclerosis, while further work connects proteomic and genomic techniques to cancer, diagnostics, and personalised medicine. Together the articles reflect quantitative proteomics as a versatile platform spanning analytical method development, model systems, and translational research.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2013

Quantitative Proteomics Using 15N SILAC Mouse

I. Chen EmilyCorresponding author
Stony Brook University, Proteomics Center, School Of Medicine, NY
Exact topic Proteomics and Genomics Research Cited by 4 doi:10.14302/issn.2326-0793.jpgr-13-252
2014

Discovery and Quantification in Mass Spectrometry-Based Proteomics

I. Chen EmilyCorresponding author
Proteomics Shared Resource at the Columbia University Medical Center, Herbert Irvine Comprehensive Cancer Center, New York, NY 10032.
Exact topic Proteomics and Genomics Research Cited by 1 doi:10.14302/issn.2326-0793.jpgr-13-357

How this research is being cited

The 12 articles above have been cited 78 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Quantitative Proteomics, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Proteomics and Genomics Research (ISSN 2326-0793).

Journal editorial board
Sutopa Dwivedi · United States Liuyang Wang · United States Juan Sainz · Spain

This page summarises published research for orientation; it is not medical or professional advice.