Hydroperoxides are organic compounds containing the functional group -OOH, in which an oxygen-oxygen single bond is attached to a hydrogen atom and an organic substituent. These reactive oxygen species play significant roles in oxidative stress, cellular damage, and various biochemical processes. Research published …
Hydroperoxides are organic compounds containing the functional group -OOH, in which an oxygen-oxygen single bond is attached to a hydrogen atom and an organic substituent. These reactive oxygen species play significant roles in oxidative stress, cellular damage, and various biochemical processes. Research published in New Developments in Chemistry has examined hydroperoxide formation and activity in several biological contexts. One study investigated the non-enzymatic generation of methylglyoxal from glucose metabolites and the subsequent production of superoxide anion radicals during cross-linking reactions, demonstrating pathways through which reactive oxygen species emerge from carbohydrate metabolism. Additional research has explored the effects of various test formulations on oxidative stress markers in cellular systems, including assessments using rat cardiomyocytes to evaluate cardiac function and studies examining biomarkers related to vital organ health. These investigations contribute to understanding how hydroperoxides and related reactive oxygen species influence cellular function and tissue integrity, with implications for metabolic disorders, cardiovascular health, and oxidative damage mechanisms. The topic remains relevant to fields spanning biochemistry, cellular physiology, and the development of interventions targeting oxidative stress pathways.
5 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The 5 articles above have been cited 51 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
A sample of recent works citing this journal's research on Hydroperoxide, linking to each citing work.