Overview
Hydrogen bonding is an attractive interaction that occurs when a hydrogen atom covalently bonded to a highly electronegative atom, typically nitrogen, oxygen, or fluorine, is drawn toward another electronegative atom bearing a lone pair of electrons. It is a particularly strong form of dipole-dipole interaction, intermediate in strength between covalent bonds and weaker van der Waals forces, and it may form between separate molecules or within a single molecule. Hydrogen bonds account for many distinctive properties of matter, including the elevated boiling point and other anomalous behaviours of water, the cohesion of many liquids, and the selective association of molecules in solution. In structural chemistry and biology they are decisive: hydrogen-bonding networks stabilise the folded conformations of proteins, the base pairing of nucleic acids, and the binding of substrates and ligands, so that disrupting such networks can alter molecular structure and function, including the catalytic activity of enzymes. Because these bonds influence vibrational and electronic behaviour, they are probed by spectroscopic techniques such as infrared and Raman analysis and modelled computationally. Hydrogen bonding also governs molecular recognition, crystal packing, and the assembly of supramolecular structures. Understanding its strength, geometry, and directional character is fundamental to chemistry, biochemistry, and materials science, linking molecular interactions to bulk and biological properties.
Research published in this journal
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Molecular Spectroscopy and Molecular Docking Studies on (E)-1-(4-Bromobenzylidene) Thiourea
Molecular Structure and Vibrational Analysis of 2-(4-methoxyphenyl)-2, 3-Dihydro-1H-Perimidine using Density Functional Theory
FT-IR, FT-Raman, Homo-Lumo and UV-Visible Spectral Analysis of E-(N′-(1H-INDOL-3YL) Methylene Isonicotinohydrazide)
Electrospun Biopolyesters: Hydrophobic Scaffolds with Favorable Biological Response
Vibrational, Ultra Violet, Natural Bond Orbital Analysis of E-1 using Quantum Mechanical Computations and Experimental Spectra.
Articular cartilage: Chemical, Physical, and Tribological Properties
Consciousness Energy Healing Treatment: Spectroscopic and Calorimetric Evaluation of the Biofield Energy Treated Hydroxypropyl β-Cyclodextrin
Supercritical Fluid Technology: A Review
How this research is being cited
The 9 articles above have been cited 107 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2027 · Fuel
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2026 · Journal of Polymers and the Environment
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2026 · Industrial & Engineering Chemistry Research
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2026 · Discover Materials
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2026 · Pharmaceutics
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2026 · Computational and Theoretical Chemistry
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2025 · Journal of Drug Delivery Science and Technology
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2025 · International Journal of Biological Macromolecules
A sample of recent works citing this journal's research on Hydrogen Bonding, linking to each citing work.