Question and contribution
Is the central reproductive-biology, gynecologic or sexual-health question clear and within scope, including related care, experience, rights and access across the lifespan? Basic and preclinical work may fit without demonstrated clinical benefit.
Methods and statistics
Are the design, model or participant selection, controls, measures, analyses and uncertainty appropriate to the research stage? Distinguish biological and technical replication in experiments, and assess context and sampling in qualitative work.
Results and interpretation
Are results reported completely, with conclusions proportionate to the evidence? Cellular and animal findings do not establish human treatment efficacy or safety, and observational associations do not by themselves establish causation.
Reporting and reproducibility
Are protocols, reporting guidelines, data availability, materials and limitations described sufficiently for evaluation and reuse?