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Cyclic peptides are expected to play a significant role in the future of drug discovery and development. Their unique properties, such as enhanced target affinity, metabolic stability, and favorable pharmokinetic profiles, make them promisin...
Issue No: 1
A procedure has been developed for synthesizing peptides in an aqueous solution with a reusable solid phase. Specifically designed linker molecule is employed to attach peptides to hydrophilic solid phases, enabling Solid Phas...
Amyloid fibrils, which are caused by abnormal conformation and the mis-assembly of proteins, are responsible for several conformational diseases, including prion diseases. To develop methods to prevent amyloi...
A new approach to protecting the side chain of lysine during solid-phase peptide synthesis in an aqueous environment is explored. The objectives of this study are twofold: 1) to reduce the consumption of chemical solvents in peptide synthesi...
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