Overview
Pain perception, or nociception followed by conscious appraisal, is the neural and psychological process by which noxious stimuli are detected, transmitted, and interpreted as pain. It begins with transduction at peripheral nociceptors, proceeds through transmission along A-delta and C fibers to the dorsal horn of the spinal cord, ascends via spinothalamic and related pathways to the thalamus and cortex, and is shaped by descending modulatory systems and by attentional, emotional, and contextual factors. This explains why identical stimuli can be experienced differently, and why pain perception is plastic, susceptible to sensitization, learning, and synaptic reorganization. Research relevant to this topic examines how pain perception modulates synaptic and somatic plasticity in the dentate gyrus, the interplay of psychological and somatic dimensions of pain, variations in perception threshold in herpetic ophthalmic neuralgia, and analgesic strategies including endogenous opioid release through music. Related work considers pain in the setting of depression and cancer, and the broader affective consequences of chronic pain. The journal publishes peer-reviewed clinical and experimental research on the neurobiology, measurement, and modulation of pain perception, integrating mechanistic studies of central plasticity with clinical investigations of how pain is experienced and managed across diverse patient populations.
Research published in this journal
12 peer-reviewed articles, ranked by relevance. Each links to its DOI.
Pain between Psyche and Soma in Uro-Andrology
Creation of Music-Induced Analgesia in Chronic Pain Patients through Endogenous Opioid Production: A Narrative Review
Combined Therapy Versus Usual Care in the Treatment of Depressed Cancer Patients with Pain
Integrating Analgesic Doses and Pain Trend Analysis: A Novel Clinical Support System
Perception Threshold Variations of Pain Area with Herpetic Ophthalmic Neuralgia
Osteoarthritis Depressive, Loneliness and Social Isolation in Later Life and the Robotic Companion
Electromagnetic Fields and Osteoarthritis 2025
Ice Water Immersion as an Additional Method in Physiology Recovery in the Sport
Chronic Pain One to Five Years after Lung Transplantation
First Lumbar Treatment of Chronic Mixed Low Back Pain with High Dose Capsaicin 8% Patch
Case Series on Chiasmal Lesions with Ocular Manifestations seen at the Eye Center of a Tertiary Government Hospital in Philippines
How this research is being cited
The 12 articles above have been cited 25 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.
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2026 · Journal of Surgical Research
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2026 · Neurology International
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2025 · Journal of Psychosomatic Research
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Kevin John D. Sy et al. · 2025 · Acta medica Philippina
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2024 · Clinical Transplantation
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M. Dalvindt et al. · 2024 · Clinical Transplantation
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2023 · International journal of psychological research
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S. Guidotti et al. · 2023 · International Journal of Psychological Research
A sample of recent works citing this journal's research on Pain Perception, linking to each citing work.