Research Topic · Peer-Reviewed

Chemoresistance

Chemoresistance is the ability of cells, particularly cancer cells, to withstand the effects of drugs intended to kill them or halt their growth. It can be present from the start of treatment or develop over time, and arises through mechanisms such as changes in drug targets, increased drug efflux from cells, enhanc…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 11× across the literature 🗓 Reviewed June 2026

Overview

Chemoresistance is the ability of cells, particularly cancer cells, to withstand the effects of drugs intended to kill them or halt their growth. It can be present from the start of treatment or develop over time, and arises through mechanisms such as changes in drug targets, increased drug efflux from cells, enhanced DNA repair, altered metabolism, and the activation of survival pathways. Chemoresistance is a major obstacle in cancer therapy, because it can render chemotherapy less effective and contribute to disease progression or relapse. Understanding and overcoming chemoresistance is a central concern of chemotherapy research, which investigates why treatments fail, how resistance emerges at the molecular and cellular level, and how new agents or combinations might restore sensitivity. Work in this area spans the study of resistance pathways, the development of selectively cytotoxic compounds, and the evaluation of approaches aimed at improving treatment response. This page gathers peer-reviewed, open-access material relevant to chemotherapy research and practice, offering a grounded reference on chemoresistance and the ongoing effort to make anticancer and other drug therapies more durable and effective.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 3 articles above have been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Chemoresistance, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Chemotherapy Research and Practice.

Journal editorial board
Monika Sakowicz-Burkiewicz · Poland M. Waheed Roomi · United States Silvia Lemma · Italy

This page summarises published research for orientation; it is not medical or professional advice.