Ubiquitin-proteasome System

Overview

The ubiquitin-proteasome system is a highly regulated process in which ubiquitin (a small protein tag) is attached to a substrate protein to mark it for degradation by the 26S proteasome. This type of protein degradation is a vital part of many cellular processes, such as cell cycle progression, signal transduction, and the regulation of protein abundance. Dysregulation of the ubiquitin-proteasome system has been implicated in many diseases, such as cancer, neurodegenerative diseases, and autoimmune diseases. Understanding how this system works can provide novel therapeutic strategies to treat these diseases.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 7 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• The decryption of BAB1 Brucella abortus antigen- BCAP31 receptor binding in oral lactococcus lactis vaccine and its effect on activation of casp-8 and IL-10 for immunogenicity
  2023 · Research Square (Research Square)
• Multi Epitopic Peptide Based Vaccine Development Targeting Immobilization Antigen of Ichthyophthirius multifiliis: A Computational Approach
  Pratik Ghosh et al. · 2022 · International Journal of Peptide Research and Therapeutics
• Multi Epitopic Peptide Based Vaccine Development Targeting Immobilization Antigen of Ichthyophthirius multifiliis: A Computational Approach
  2022 · International Journal of Peptide Research and Therapeutics
• In Silico Comparison of Separate or Combinatorial Effects of Potential Inhibitors of the SARS-CoV-2 Binding Site of ACE2
  M. Shakhsi-Niaei et al. · 2021 · Iranian Journal of Public Health
• In Silico Comparison of Separate or Combinatorial Effects of Potential Inhibitors of the SARS-CoV-2 Binding Site of ACE2
  2021 · Iranian Journal of Public Health
• In Silico Epitope-Based Peptide Vaccine Design against Invasive Non Typhoidal Salmonella (iNTS) Through Immunoinformatic Approaches
  M. Ali et al. · 2020 ·
• In Silico Epitope-Based Peptide Vaccine Design against Invasive Non Typhoidal <em>Salmonella </em>(iNTS) Through Immunoinformatic Approaches
  2020 ·

A sample of recent works citing this journal's research on Ubiquitin-proteasome System, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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