Totipotency

Overview

Totipotency is the ability of a single cell to divide and develop into any other type of cell, tissue, or organ. It represents a remarkable property of some cells, allowing them to regenerate entire organs, thus providing the basis for regenerative medicine. Totipotent cells are found in the early embryo, especially the zygote and embryonic stem cells, where they are responsible for the formation of the basic body plan. As cells differentiate during development, they gradually lose the ability to form all types of cells, and eventually become restricted to fewer types. Totipotency is an important tool for scientists as it allows them to study the pathways and mechanisms of development, and to explore the possibilities for regenerative treatments. Additionally, it can be used for creating genetically modified organisms and for the production of therapeutic proteins.

Research published in this journal

1 peer-reviewed article, ranked by relevance. Each links to its DOI.

How this research is being cited

The 1 article above has been cited 11 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

• CELL CYCLE STRESS IN NORMAL HUMAN CELLS: A ROUTE TO "FIRST CELLS" (WITH/WITHOUT FITNESS GAIN) AND CANCER-LIKE CELL-SHAPE CHANGES.
  K. Walen · 2021 · Seminars in Cancer Biology
• Is an Ancient Genome Repair Mechanism the Trojan Horse of Cancer?
  V. Niculescu · 2021 · Novel Approaches in Cancer Study
• Is an Ancient Genome Repair Mechanism the Trojan Horse of Cancer?
  2021 · Novel Approaches in Cancer Study
• Cell cycle stress in normal human cells: A route to “first cells” (with/without fitness gain) and cancer-like cell-shape changes
  2021 · Seminars in Cancer Biology
• aCLS cancers: genomic and epigenetic changes transform the cell of origin of cancer into a tumorigenic pathogen of unicellular organization and lifestyle.
  V. Niculescu · 2020 · Gene
• Is Cancer Cell Reversion to Normalcy Possible? Un Update
  V. Niculescu · 2020 · Novel Approaches in Cancer Study
• Is Cancer Cell Reversion to Normalcy Possible? Un Update
  2020 · Novel Approaches in Cancer Study
• The reproductive life cycle of cancer: Hypotheses of cell of origin, TP53 drivers and stem cell conversions in the light of the atavistic cancer cell theory.
  V. Niculescu · 2019 · Medical Hypotheses

A sample of recent works citing this journal's research on Totipotency, linking to each citing work.

This page summarises published research for orientation; it is not medical or professional advice.

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