Research Topic · Peer-Reviewed

Pyruvate

Kinase Pyruvate Kinase (PK) is an enzyme essential for the process of aerobic respiration in cells. It catalyzes the final step of glycolysis, which is the conversion of Pyruvate to Phosphoenolpyruvate (PEP). This reaction is highly exergonic, releasing energy in the form of ATP which is used to power the cell's me…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 53× across the literature 🗓 Reviewed June 2026

Overview

Kinase Pyruvate Kinase (PK) is an enzyme essential for the process of aerobic respiration in cells. It catalyzes the final step of glycolysis, which is the conversion of Pyruvate to Phosphoenolpyruvate (PEP). This reaction is highly exergonic, releasing energy in the form of ATP which is used to power the cell's metabolic processes. Pyruvate Kinase is also responsible for regulating the flow of carbon compounds between different metabolic pathways. Its activity is tightly regulated in the body, so any deficiencies in this enzyme can lead to a host of medical issues such as anemia, muscular dystrophy, and cancer. Pyruvate Kinase has become an important target in the development of new drugs and therapies, as it is involved in many metabolic pathways.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 53 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Pyruvate, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Cell.

Journal editorial board
Faiz Ul Amin · Korea, Democratic People's Rep Yuping Li · United States Hong WAN · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.