Research Topic · Peer-Reviewed

Notch Signaling

Notch signaling is a process in multicellular organisms that helps regulate the development and progression of a wide range of activities, including cell fate determination, differentiation, proliferation, and apoptosis. This process relies on binding between transmembrane receptors and ligands on adjacent cells. No…

Curated from this journal's research 📚 2 peer-reviewed articles cited Cited 2× across the literature 🗓 Reviewed June 2026

Overview

Notch signaling is a process in multicellular organisms that helps regulate the development and progression of a wide range of activities, including cell fate determination, differentiation, proliferation, and apoptosis. This process relies on binding between transmembrane receptors and ligands on adjacent cells. Notch signaling is critical for many developmental processes and for the maintenance of tissue homeostasis in adult animals. It is involved in processes such as the formation of embryonic organs, neuronal development, cell-fate specification, and lymphogenesis. In addition, Notch signaling is believed to play a role in cancer, as it has been linked to various tumor types. Understanding the Notch signaling pathway is therefore essential for the development of treatments for various diseases.

Research published in this journal

2 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 2 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Notch Signaling, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Cell.

Journal editorial board
Faiz Ul Amin · Korea, Democratic People's Rep Yuping Li · United States Hong WAN · United Kingdom

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