Overview
Juxtacrine signaling is a form of intercellular communication in which two cells, usually adjacent to each other, are able to exchange information without the intervention of a hormone or other outside chemical. This type of communication is important in the development of many tissues and organs and is essential for normal cell function. Through juxtacrine signaling, cells can regulate the production of specific proteins which are necessary for cell growth, differentiation and survival. Moreover, juxtacrine signaling is important in the coordination of the body’s immune response, as well as in the initiation of cell death, such as during apoptosis. Because of its ubiquitous nature and broad range of applications, juxtacrine signaling is a key area of research in the fields of biology and medicine.