Research Topic · Peer-Reviewed

Germline Mutation

Germline mutation is a genetic mutation that occurs during the formation of gametes or reproductive cells (sperm, eggs) and is passed from parent to child. It is a permanent change to the germline, passed on from generation to generation, and can be the cause of genetic diseases or abnormalities. It can also increas…

Curated from this journal's research 📚 3 peer-reviewed articles cited Cited 2× across the literature 🗓 Reviewed June 2026

Overview

Germline mutation is a genetic mutation that occurs during the formation of gametes or reproductive cells (sperm, eggs) and is passed from parent to child. It is a permanent change to the germline, passed on from generation to generation, and can be the cause of genetic diseases or abnormalities. It can also increase the risk of cancer in adults. Germline mutations have been studied to understand the genetic basis of diseases and to develop therapeutic strategies for their treatment. They have also been used in genetic screening for inherited diseases and for gene therapy.

Research published in this journal

3 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 3 articles above have been cited 2 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Germline Mutation, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Cell.

Journal editorial board
Faiz Ul Amin · Korea, Democratic People's Rep Yuping Li · United States Hong WAN · United Kingdom

This page summarises published research for orientation; it is not medical or professional advice.