Research Topic · Peer-Reviewed

Gamma-aminobutyric Acid

Gamma-aminobutyric acid (GABA) is a naturally occurring amino acid that functions as the primary inhibitory neurotransmitter in the central nervous system, regulating neuronal excitability and playing essential roles in brain function and metabolic processes. Research published in the International Journal of Amino …

Curated from this journal's research 📚 4 peer-reviewed articles cited Cited 10× across the literature 🗓 Reviewed June 2026

Overview

Gamma-aminobutyric acid (GABA) is a naturally occurring amino acid that functions as the primary inhibitory neurotransmitter in the central nervous system, regulating neuronal excitability and playing essential roles in brain function and metabolic processes. Research published in the International Journal of Amino Acids examines GABA through multiple clinical and biochemical perspectives. Studies have investigated genetic polymorphisms in epilepsy patients, exploring how variations in genes related to GABAergic neurotransmission may influence seizure susceptibility. Additional work has examined brain hemodynamics and cerebrovascular reactivity in tension-type headache patients, conditions where GABAergic dysfunction may contribute to pathophysiology. The journal has also published research on nutritional interventions, including analysis of kale powder consumption in subjects with potential metabolic syndrome, relevant given GABA's presence in certain plant foods and its proposed metabolic effects. Further investigations have explored physicochemical and thermal properties of pyridoxine hydrochloride, a compound significant to GABA metabolism as pyridoxine serves as a cofactor for glutamic acid decarboxylase, the enzyme responsible for GABA synthesis. This body of work reflects the amino acid's importance across neurological disorders, vascular regulation, and nutritional biochemistry.

Research published in this journal

4 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 4 articles above have been cited 10 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Gamma-aminobutyric Acid, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in International Journal of Amino Acids.

Journal editorial board
Nicolas Inguimbert · France

This page summarises published research for orientation; it is not medical or professional advice.