Research Topic · Peer-Reviewed

Heart Failure

Heart failure is a clinical syndrome in which the heart cannot pump blood at a rate sufficient to meet the metabolic demands of the body, or can do so only at elevated filling pressures, resulting in congestion, reduced exercise capacity, and impaired organ perfusion. It is the common endpoint of diverse cardiac ins…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 38× across the literature 🗓 Reviewed July 2026

Overview

Heart failure is a clinical syndrome in which the heart cannot pump blood at a rate sufficient to meet the metabolic demands of the body, or can do so only at elevated filling pressures, resulting in congestion, reduced exercise capacity, and impaired organ perfusion. It is the common endpoint of diverse cardiac insults, including coronary artery disease, hypertension, valvular and rheumatic disease, congenital defects, and cardiomyopathy. The studies gathered here examine heart failure across its causes, mechanisms, and management. Clinical contributions address heart failure in family-medicine practice, rheumatic heart disease, atypical constrictive pericarditis after transplantation, and structural abnormalities such as Ebstein's anomaly complicated by thrombus. Mechanistic and translational work explores cardiorenal signalling pathways underlying the syndrome, microRNA-based therapeutic strategies in ischaemic heart disease, and the prospects and current status of gene therapy for heart failure. Diagnostic and monitoring themes appear through ambulatory acoustic cardiography for assessing cardiac function and sleep-disordered breathing. Related interventional and experimental studies consider percutaneous coronary intervention in chronic total occlusion and in-vitro assessment of cardiac function using cardiomyocyte cell lines. Together these themes present heart failure as a progressive, multifactorial disorder whose understanding spans cardiorenal physiology, genetics, and emerging therapeutics, and whose management integrates lifestyle modification, pharmacotherapy, device monitoring, and treatment of the underlying cardiac disease.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

2020

Heart Failure in Family Medicine

Franjić SinišaCorresponding author
Exact topic International Journal of Global Health Cited by 3 doi:10.14302/issn.2693-1176.ijgh-20-3411

How this research is being cited

The 12 articles above have been cited 38 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Jun 2026.

A sample of recent works citing this journal's research on Heart Failure, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Blood Pressure.

Journal editorial board
Silvio Maringhini · Italy

This page summarises published research for orientation; it is not medical or professional advice.