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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IPJ</journal-id>
      <journal-title-group>
        <journal-title>International Physiology Journal</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2578-8590</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">IPJ-18-2547</article-id>
      <article-id pub-id-type="doi">10.14302/issn.2578-8590.ipj-18-2547</article-id>
      <article-categories>
        <subj-group>
          <subject>in-brief</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Why People With Liver (or hepatic ) Cancer Should Die in Short - Time?</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Nasim</surname>
            <given-names>Habibzadeh</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842869756">1</xref>
          <xref ref-type="aff" rid="idm1842868100">*</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842869756">
        <label>1</label>
        <addr-line>PhD in Sport Science, Department of Sport Science, Teesside University, UK</addr-line>
      </aff>
      <aff id="idm1842868100">
        <label>*</label>
        <addr-line>Corresponding author</addr-line>
      </aff>
      <author-notes>
        <corresp>
  Nasim Habibzadeh, <addr-line>PhD in Sport Science, Department of Sport Science, Teesside           University, UK</addr-line>, Email: <email>nasimhabibzadeh@yahoo.com</email></corresp>
        <fn fn-type="conflict" id="idm1843376404">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2018-12-14">
        <day>14</day>
        <month>12</month>
        <year>2018</year>
      </pub-date>
      <volume>2</volume>
      <issue>1</issue>
      <fpage>9</fpage>
      <lpage>10</lpage>
      <history>
        <date date-type="received">
          <day>14</day>
          <month>12</month>
          <year>2018</year>
        </date>
        <date date-type="accepted">
          <day>14</day>
          <month>12</month>
          <year>2018</year>
        </date>
        <date date-type="online">
          <day>14</day>
          <month>12</month>
          <year>2018</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2018</copyright-year>
        <copyright-holder>Nasim Habibzadeh</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org/ipj/article/931">This article is available from http://openaccesspub.org/ipj/article/931</self-uri>
      <abstract>
        <p>This opinion challenges fatalistic framing of hepatic cancer prognosis. It advocates for nuanced discussion of staging, treatment advances, and supportive care, with clear communication to patients and families.</p>
      </abstract>
      <kwd-group>
        <kwd>Cancer</kwd>
      </kwd-group>
      <counts>
        <fig-count count="0"/>
        <table-count count="0"/>
        <page-count count="2"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1842736836" sec-type="intro">
      <title>Introduction</title>
      <p>The world population are rapidly increasing per second (60 sec) and this means  human numbers increase every 24 hours .Overall total world population is 7 billion now. Net increase in world population is along with increased demands for health and well-being services. The requisite for national - health care system in part is highly growing for aged population <xref ref-type="bibr" rid="ridm1849784116">1</xref>.</p>
      <p>The demand of ageing population at the end of life account for major concerns for health and social care systems since some of the elderly in old age have to challenge with dramatically health conditions such as uncurable cancers <xref ref-type="bibr" rid="ridm1849785052">2</xref>. Cancers problems are a cross national cancers nowadays and dimensions of cancer burden are challenges ahead in wide ranges <xref ref-type="bibr" rid="ridm1849795468">3</xref>.</p>
      <p>Aging account for an important risk factors for cancers and some elderly health ‘needs never could be reported and the cancers can simply develop among them <xref ref-type="bibr" rid="ridm1849882964">4</xref>.This impeding situation can be associated  with different medical, social and economic issues <xref ref-type="bibr" rid="ridm1849642084">5</xref>.</p>
      <p>Older adults have weaker immune system and frail to impact different cancers. In this relation ,some cells in human body with advancing old age can grow multiple than usual which can affect other organs and enhance the chance of getting cancers. A destructive phenomenon  such as virus  and chronic inflammation also that is hard to eradicate can impact elderly to get cancer <xref ref-type="bibr" rid="ridm1849644460">6</xref><xref ref-type="bibr" rid="ridm1849630180">7</xref> .</p>
      <p>Poor dietary habits directly can devolve several cancers in old people. Some kind of diets such as processed and red meat and salt-preserved foods, can increase the risk of developing cancer in older adults whilst others foods high in fibre such as fruits, vegetables and can reduce the risk of different                    cancer <xref ref-type="bibr" rid="ridm1849624564">8</xref>. Some other widespread factors such as some cancer-causing chemicals, radiation, obesity, hormones, and lack of exercise and smoking progress various cancers <xref ref-type="bibr" rid="ridm1849622764">9</xref>.</p>
      <p>Among different cancer chronic kidney disease such as liver or hepatic cancer is common cancer between elderly nowadays. In individual with live cancer, the liver totally will be damaged and  will not have any function anymore. Weaker immunome in elderly system and inappropriate diets (i.e. Salty food and lack of vitamin B&amp;C) and poor healthy life style are main factors at which develop liver cancers <xref ref-type="bibr" rid="ridm1849616612">10</xref>.</p>
      <p>Chemotherapy is common treatment with drugs to destroy cancer cells in patient with liver cancers. It is believed ,chemotherapy is a powerful cancer-killing medications to slow the spread of liver cancer. There are also other different treatments for liver cancer including surgery and specific drugs ,although it depends on in what stage the liver cancer patient is  (i.e. primality or secondary) <xref ref-type="bibr" rid="ridm1849614164">11</xref>.</p>
      <p>However,  chemotherapy and surgery  and other targeted drugs are always not successful to keep the patient with liver cancer alive for a long time and in many cases the patients with liver cancer die in                 short-term. With advancing age older adults (i.e. After 50 year) are required to have  free -ultrasound scan every year to diagnosis any unwanted illness  such cancers. In early stage any disease  such as cancers can be prevented or cured. The worldwide attempts are required to increase life - span and save the life of many elderly induvial in this conditions. Exploring other conventual therapy which could combat and destroy the liver cancer is necessitate also.</p>
    </sec>
  </body>
  <back>
    <ack>
      <p>I devote this article to my mother soul which dead from liver cancer in short- term . I hope this could be prevented for other individual with the same               conditions.</p>
    </ack>
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