<?xml version="1.0" encoding="utf8"?>
 <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd"> <article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.0" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JWC</journal-id>
      <journal-title-group>
        <journal-title>Journal of Weather Changes</journal-title>
      </journal-title-group>
      <issn pub-type="epub">3070-3379</issn>
      <issn pub-type="ppub">3070-3379</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.14302/issn.3070-3379.jwc-25-5549</article-id>
      <article-id pub-id-type="publisher-id">JWC-25-5549</article-id>
      <article-categories>
        <subj-group>
          <subject>research-article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Vulnerabilities in Environment and Health Due to Climate Change and Extreme Hydrological Events: Determinants for Risk Reduction</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Chrysanthus</surname>
            <given-names>Chukwuma Sr</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842479716">1</xref>
          <xref ref-type="aff" rid="idm1842477916">*</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842479716">
        <label>1</label>
        <addr-line>The Centre for Future-oriented Studies Abakaliki, Ebonyi State, Nigeria.</addr-line>
      </aff>
      <aff id="idm1842477916">
        <label>*</label>
        <addr-line>Corresponding Author </addr-line>
      </aff>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Sasho</surname>
            <given-names>Stoleski</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842340220">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842340220">
        <label>1</label>
        <addr-line>Institute of Occupational Health of R. Macedonia, WHO CC and Ga2len CC.</addr-line>
      </aff>
      <author-notes>
        <corresp>
  Chrysanthus Chukwuma Sr, <addr-line>The Centre for Future-oriented Studies </addr-line><addr-line>Abakaliki</addr-line><addr-line>, Ebonyi State, Nigeria</addr-line>, <email>chukwumasr@gmail.com</email></corresp>
        <fn fn-type="conflict" id="idm1842065820">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2025-11-05">
        <day>05</day>
        <month>11</month>
        <year>2025</year>
      </pub-date>
      <volume>1</volume>
      <issue>2</issue>
      <fpage>1</fpage>
      <lpage>10</lpage>
      <history>
        <date date-type="received">
          <day>15</day>
          <month>05</month>
          <year>2025</year>
        </date>
        <date date-type="accepted">
          <day>30</day>
          <month>06</month>
          <year>2025</year>
        </date>
        <date date-type="online">
          <day>05</day>
          <month>11</month>
          <year>2025</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2025</copyright-year>
        <copyright-holder>Chrysanthus Chukwuma Sr</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org/jwc/article/2235">This article is available from http://openaccesspub.org/jwc/article/2235</self-uri>
      <abstract>
        <p>This short communication/mini-review immensely emphasizes human health to explicate and elucidate management of the global scourge associated with the determinants and impact of vulnerabilities to extreme hydrologic events and    climate change in the absence of risk reduction and their concomitant sequelae. The most effective approach for risk reduction associated with biodiversity,    environmental, and health vulnerabilities due to climate change and extreme   hydrological events, an ecological framework must take into cognizance                      exposure, vulnerability, and resilience. This framework emphasizes the           significance of understanding the inextricable linkage between ecosystems and human communities are exposed and susceptible to hazards, sensitivity to these hazards, and capacity to cope, adapt and recuperate. Risk reduction incorporates structurally attenuating exposure, strengthening resilience, and sustainably      enhancing overall vulnerability management. Extreme weather and climate-associated incidents impinge on human health with consequential morbidity,  mortality and socioeconomic challenges and constraints. Climate change and  extreme event have altered the frequency, intensity, geographic distribution, and propensity as drivers for change in the future. The indicted variables include             hydrological events, such as precipitation, floods and droughts as well as heat waves, wildfires, global warming, extreme temperatures, and hurricanes. The pathways inextricably-linked with extreme events to economic dissipation,               human health prognosis and outcomes remain inexplicably diverse and complex; and thus, difficult to predict  due to their emergence and reemergence from local, societal and environmental factors which influence disease burden. </p>
      </abstract>
      <kwd-group>
        <kwd>infectious diseases</kwd>
        <kwd>morbidity</kwd>
        <kwd>mortality</kwd>
        <kwd>agriculture</kwd>
        <kwd>food security</kwd>
        <kwd>adaptation</kwd>
        <kwd>geopolitics</kwd>
        <kwd>international cooperation</kwd>
        <kwd>global warming</kwd>
        <kwd>floods</kwd>
        <kwd>droughts</kwd>
      </kwd-group>
      <counts>
        <fig-count count="0"/>
        <table-count count="0"/>
        <page-count count="10"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1842345260" sec-type="intro">
      <title>Introduction </title>
      <p>The determinants of health and climate change depict the latter as having greater impact on the health of the elderly, children, women, artisans and other            vulnerable individuals due to heat, stress, injury sustained in extreme weather presentations, exacerbated water and vector-borne infectious diseases <xref ref-type="bibr" rid="ridm1842185788">1</xref><xref ref-type="bibr" rid="ridm1842248788">2</xref><xref ref-type="bibr" rid="ridm1842257572">3</xref><xref ref-type="bibr" rid="ridm1842044148">4</xref>. Health impacts associated with climate change in extreme events include        morbidity, mortality and exacerbated underlying medical stance may be attributed to hydrological extremes detected using disparate observation modalities,                  investigations and modeling datasets. Assessment of climate change and effects on hydrologic             extremes, the attendant risks and implications locally, regionally and globally, exhibit incessant              disaster and climate risks which are incessantly emerging from climate change, leading to profound frequency and severity in weather events <xref ref-type="bibr" rid="ridm1842042636">5</xref>. These risks negatively impact the spheres of human           endeavors in varied aspects of  biodiversity, health, well-being, welfare, infrastructure, and                         ecosystems <xref ref-type="bibr" rid="ridm1842038676">6</xref><xref ref-type="bibr" rid="ridm1842034068">7</xref><xref ref-type="bibr" rid="ridm1842028596">8</xref>,with likely exacerbation of the duration of extreme weather events and population exposure. Adaptation strategies, efforts in disaster risk reduction, and risk-informed data are crucial for managing these future risks <xref ref-type="bibr" rid="ridm1842019540">9</xref>.</p>
      <sec id="idm1842345980">
        <title>Certain parameters for determinants and risk reduction </title>
        <p>The reductions of exposures to hazards, attenuating vulnerabilities of the populace and property,     sustainable management practices of land and the environment, as well as improved forewarned      preparatory ventures against adverse events constitute disaster risk reduction. Climate change and   extreme hydrologic events, such as droughts and floods exacerbate vulnerabilities in biodiversity, the environment and health, precipitating a plethora of risk reduction processes <xref ref-type="bibr" rid="ridm1842023572">10</xref>. This ecological framework expounds the pattern of extreme hydrological events and climate change in the alterations of ecosystem services and dynamics, influencing species spread, community aggregation, and         consequentially the affect on biodiversity, environment and human health as depicted in water                    scarcity, food security, and disease dissemination. The determinants of risk reduction concerning  environmental and health vulnerabilities to extreme hydrological events and climate change are                    associated with decreasing exposure, augmenting vulnerability, and creating resilience. Instances of these determinants inculcated land use planning, enhanced infrastructure, improved adaptive capacity, and sustainable  disaster risk management enforcement. These determinants pave the practice,                        capacity, capability and concept of the populace, communities, and ecosystems to confront and                survive the untoward impacts of climate change. Climate change and the modifying patterns of                extreme weather can expunge or suppress the sustainability of public health .</p>
      </sec>
      <sec id="idm1842345692">
        <title>Extant challenges for sustainable land and water resources</title>
        <p>Prevailing challenges in sustainable land and water management, such as environmental and land    degradation <xref ref-type="bibr" rid="ridm1842000180">11</xref>, water deprivation <xref ref-type="bibr" rid="ridm1841997444">12</xref> and climate change provide opportunities for novel                                    sustainable development. The instant challenges to be focused on are the trade-offs of the cost-benefit analysis in the short-run and long-run, respectively, or sustainable approaches and funding acquisition for projects, especially in the private sector. Opportunities correlate with the development of                      innovative business models, water resource integration and management within land use planning, and community-dependent strategies promotion. Potable water, food and energy security, climate change, water-borne diseases, water-associated hazard management, sustainable environmental                   quality and land use  management are present and future challenges <xref ref-type="bibr" rid="ridm1841997444">12</xref><xref ref-type="bibr" rid="ridm1841994852">13</xref>. The ongoing challenge for sustainable land and water management, climate change adaptation and mitigation projects is proper acquisition of Sustainable Land Management (SLM) concerning land degradation rates, and preventative measures against desertification in coordination for greener and more sustainable future, and aggregated efforts to  obviate distortions, such as water unavailability, pollution, ecosystem                   cadastral <xref ref-type="bibr" rid="ridm1842004788">14</xref> degradation and anomalous environmental health trajectories <xref ref-type="bibr" rid="ridm1841980204">15</xref>. </p>
        <p>Understanding the associated characterizations with these extreme hydrological events is pertinent for precise risk assessment in the design and operation of water infrastructures. Inappropriate assessment of design floods leads to material and  human life disruption. Thus, extreme weather events                            incessantly augment, and are correlated to global warming. The dissipation of biodiversity                       incorporates land-use change, suppressed habitat, excessive exploitation, pollution, species                                   invasiveness or inhibition and climate change. These weather events are ostensibly contributory to, and enhance risks for expansive spectra of vector- and non-vector-borne diseases and infestations to fauna and flora with concomitant anomalous complications. As these pivotal determinants are placed on focus, individuals and communities are positioned to ameliorate vulnerabilities to extreme                    hydrological events and climate change, with resultant improvement of biodiversity, environment and health. </p>
      </sec>
      <sec id="idm1842344468">
        <title>Hydrological vulnerabilities, climate change and precipitation </title>
        <p>The hydrologic vulnerability correlates with the response of the natural and anthropogenic which               depict aspects of geographical precincts to the impact of extreme hydrological phenomena.                          Hydrologic perturbations are  extreme events <xref ref-type="bibr" rid="ridm1842019540">9</xref> associated with water occurrence, motion, hazards, flooding, droughts and related events, such as landslides, river scour and deposition. These function  as a framework for resourceful and safe drinking water and health in endpoint characterization                         variables concerning water usage on human health <xref ref-type="bibr" rid="ridm1841994852">13</xref>. The hydrological cycle has been profoundly  affected  by climate change. Climate-induced hydrological extremes, such as floods and droughts, have been overwhelming in past decades, with the trajectory and trend prominently unabated into the future. Droughts and floods are both extreme weather events associated with climate change,                                  presenting extensive repercussions for communities, biodiversity, ecosystems, economies and health. Droughts result in water scarcity, with adverse effects on agriculture, energy production, and                             ecosystem health. The devastating impacts of floods include contamination and pollution of water sources, infrastructure degradation, and displacement of persons. The World Health Organization (WHO) is concerned that flood is a risk factor in cholera transmission of cholera but drought is not explicitly given due cognizance <xref ref-type="bibr" rid="ridm1841994852">13</xref><xref ref-type="bibr" rid="ridm1841976388">16</xref><xref ref-type="bibr" rid="ridm1841974876">17</xref>. </p>
        <p>Climate change substantially alters the pattern of precipitation, resulting in both elevated intensity and frequency of extreme precipitation events and modifications in total quantities of precipitation. The augmentation of the atmospheric water holding capacity due to warming leads to exacerbated intense storms and enhancing flooding risk. Concomitantly, warming culminates in elevated evaporation,    leading to drier states in certain ambientes with drought intensification. The scenario of respective    superimposed wetness and dryness are evidenced in the effects of climate change on precipitation<xref ref-type="bibr" rid="ridm1841986900">18</xref>. Invariably, alterations in precipitation or climate impact on health. Expansive wildfires tending to    extreme temperatures, and decrement in precipitation can lead to rising ozone and particulate matter, exacerbating in cardiovascular threats or risks. However, certain populations exhibit more                               vulnerability to climatic health challenges <xref ref-type="bibr" rid="ridm1841982724">19</xref>. </p>
      </sec>
      <sec id="idm1842342452">
        <title>Crop growth, soil quality, and agricultural productivity</title>
        <p>Extreme precipitation events may induce aberrant effects on crop growth, soil quality, and agricultural productivity <xref ref-type="bibr" rid="ridm1841961068">20</xref><xref ref-type="bibr" rid="ridm1841959124">21</xref>. On the other hand, climate change leads to higher temperatures, accelerated  water evaporation, and decreased soil moisture, and subsequently affects the water use efficiency of crops. Dryland rivers and streams contribute significantly in the dynamics of dryland ecosystem food web, with impact on biodiversity and food security. Hydrologic variability that characterizes dryland areas, critically impacts these systems, by regulating both terrestrial and aquatic food webs and the dependent organisms. Climate change constitutes a veritable influence in the availability, quality and diversity of food, and nutritional crises. There are standard strategies to explicate and understand                indicators for   river health in variable systems <xref ref-type="bibr" rid="ridm1841954948">22</xref><xref ref-type="bibr" rid="ridm1841953940">23</xref><xref ref-type="bibr" rid="ridm1841951060">24</xref>. Due to the extreme hydrological variability and opportunistic biotic responses to flood pulses, dryland rivers are accommodating to specific food webs. In these systems, primary productivity and heterotrophy are important for food web                                         sustainability<xref ref-type="bibr" rid="ridm1841930060">25</xref><xref ref-type="bibr" rid="ridm1841926460">26</xref>. Flows provide rewetting and upstream delivery, accompanied by episodic                 particulate and dissolved resources, with frequent autochthonous formation, within a short  period                 generating an expansive biomass<xref ref-type="bibr" rid="ridm1841923220">27</xref>. The biomass preponderance can result in high quantities of                secondary production. It is suggestive that dryland river food webs depict resistant multiscale                      backbones<xref ref-type="bibr" rid="ridm1841934668">28</xref> which undergird the persistence of the primordial and pivotal ecological functionalities in these systems in drought. </p>
        <p>The tolerance of plants to flooding and submergence broadly varies, with certain species depicting high sensitivity, whereas other species exhibit thriving adaptability in flood-prone ambientes. The health of the root is important for crop survival and yield during flooding <xref ref-type="bibr" rid="ridm1841903892">29</xref>. Pivotal adaptations incorporate structural and functional alterations, such as aerenchyma production, that propagates oxygen transport, and physiological adaptations as aggravated hypoxia tolerance. For instance, rice is a highly tolerant species, whereas a vast majority of crops exhibit elevated sensitivity. In rice, enhanced flooding  tolerance requires a combined tolerance of submergence and stagnant flooding. Agricultural ambientes are susceptible to flooding and ponding due to the excessive precipitation and hydrologic extremes. Within this milieu, plant breeders profoundly identify and develop genetic technologies to augment crop productivity. Rice maintains a veritable position in breeding as regards crop tolerance <xref ref-type="bibr" rid="ridm1841903892">29</xref> to flooding. Numerous rice cultivars merely tolerate flooding for circa a week. However, a class of ethylene-response-factor-like genes is associated in flooding/submergence tolerance <xref ref-type="bibr" rid="ridm1841902236">30</xref>. The         accumulation of ethylene retards cytokine-mediated senescence and instigates dormancy in              submergence. In addition, climate change aggravates the frequency and intensity of these events,     culminating in elevated challenges for agricultural systems and production. Extreme weather events caused by the ENSO cycle or El Niño-Southern Oscillation can affect health via associated droughts, floods, heat waves, and distortions in food supply <xref ref-type="bibr" rid="ridm1841899932">31</xref>.  Thus, extreme weather events associated with the El Niño-Southern Oscillation (ENSO) can remarkably affect public health. ENSO-related droughts, floods,, elevate the risk of exacerbating extant health vulnerabilities. The health risks of climate change emerge from  interactions of the dangers associated with a changing climate, for instance, increased frequency and intensity of extreme weather events, the susceptible communities exposed to the  hazards, the vulnerability of regions to adverse health impacts on exposure, and the potential to be aware against these events, and cope with the hazard <xref ref-type="bibr" rid="ridm1841899932">31</xref>. </p>
        <p>Climate change may induce disruptive healthcare access, and risk vulnerabilities to physical and mental health well-being and hygiene. The health impacts of the disruptions, such as increased                    cardiopulmonary disorders, wounds and premature mortality-associated extreme weather events,     alterations in demographics of food- and water-borne morbidities and comorbidities, the emergence and reemergence of infectious diseases <xref ref-type="bibr" rid="ridm1841893668">32</xref><xref ref-type="bibr" rid="ridm1841890860">33</xref> unravel expansive interventions in public policies and administration <xref ref-type="bibr" rid="ridm1841887692">34</xref>. Climate change may disorient cardiovascular health via multiple pathways.      Environmental stressor exposure causes physiological alterations, such as accelerated heart rate and altered plasma viscosity in association with extreme heat, local and systemic inflammation exposures from airborne particulate matter inhalation <xref ref-type="bibr" rid="ridm1841884308">35</xref><xref ref-type="bibr" rid="ridm1841881644">36</xref>. Environmental temperature constitutes the most intensively researched phenomenon. The association between mortality, cardiovascular disorder                   incidence, and temperature depicts graphically as the "U" alphabet. The invariable association of cold, heat and heat wave exposures with elevated risk of acute coronary syndromes has been  documented <xref ref-type="bibr" rid="ridm1841875380">37</xref>. Extreme temperature exposure poses a significant impact on food intake and nutrient                        composition. Extreme temperatures impact on eating habits through enhancing the tendency to imbibe high-fat diets, although, the total calorie consumption is relatively unperturbed. This shift presents  adverse health risks in obesity, diabetes, and cardiovascular diseases<xref ref-type="bibr" rid="ridm1841857180">38</xref><xref ref-type="bibr" rid="ridm1841853868">39</xref><xref ref-type="bibr" rid="ridm1841851204">40</xref>. It was observed in both hot and cold weather, persons are induced to consume more fat, especially with more impact on vulnerable groups, such as rural dwellers and the low-educated populace. As cooling fans and heating systems as adaptation resources, tend to ameliorate the effects, broader policy interventions are       pertinent. In essence,, short-run exposure to extreme temperatures modifies dietary patterns by        augmenting fat consumption, even with total calorie intake is constant. Driven by physiological       appetite regulation, this shift augments the risk of high-fat diets and diet-associated disorders,          particularly within the vulnerable population. These findings may correlate with short-term dietary           modifications, and further research is pertinent to understand longer-run implications <xref ref-type="bibr" rid="ridm1841851204">40</xref>. </p>
        <p>The intensification of the hydrological cycle could result as global warming instantaneously escalates mechanisms associated with the hydrologic cycle with resultant intense droughts, floods and wet     periods which impact health, environment, biodiversity and societal sustainability. Warmer             temperatures and shifting weather patterns disrupt air quality which precipitate to cardiopulmonary health deficits and asthmatic presentations. Predictable increased severity, quantity and extent of     wildfires with the concomitant smoke alongside climate change, including aberrant  or health          debilitating atmospheric pollutants. Extreme weather events invariably affect human health by causing injuries, dissipation of human lives, diseases, psychiatric disorders and comorbidities. There are      geopolitical trends and convergence in health and environment of countries on the scientific parameters of climate change but variance and divergence sustain on which country is the most culpable, the ways and means to predict and track the decrement of the emissions regarding risk reduction, and the       rationale for the compensation of vulnerable geopolitical areas. </p>
        <p>Considering climate-driven dietary modification is pertinent to safeguard long-run public health in a global accelerating warming ambient. Climate vulnerabilities have ostensibly been principally induced by anthropogenic activities on climate change and global warming, with incessant exclusivity of     superimposed threats due to carbon dioxide emissions, population growth and energy sources from stressors accrued from the emergence of global affluence <xref ref-type="bibr" rid="ridm1841839828">43</xref><xref ref-type="bibr" rid="ridm1841837884">44</xref> and deplorable health conditions. It is crucial to evaluate all encompassing threats by employing the bottom-up model on sustainable food resources, ecosystems <xref ref-type="bibr" rid="ridm1842004788">14</xref>, energy, human health <xref ref-type="bibr" rid="ridm1841835364">45</xref><xref ref-type="bibr" rid="ridm1841864524">46</xref>, through configuring water threats, exploring preventive measures and adaptations <xref ref-type="bibr" rid="ridm1842042636">5</xref>. The adaptation to extreme events necessitates a                 multi-dimensional approach by addressing risk management, health and hydrological issues. This    requires investment in infrastructure, implementation of early warning systems, and promotion of community-based adaptation procedures. Health impacts of these events, necessitate cooperation     between stakeholders, such as governments and communities, with appropriate healthcare facilities.    Essentially, extreme weather events constitute health hazards <xref ref-type="bibr" rid="ridm1842042636">5</xref>. </p>
      </sec>
    </sec>
    <sec id="idm1842342524" sec-type="discussion">
      <title>Discussion </title>
      <p>This article provides current drivers and typologies of extremes in disparate geopolitical arenas with highlights, challenges, constraints, issues and opportunities in inter alia predicting and forecasting   hydrological extremes spatiotemporally. Risk reduction pertains to choices or inalienable rights of reducing exposure to hazards, abating vulnerability of people and property, sustainable management of land and the environment, as well as improving awareness and early warning systems against          deranging events in disaster risk reduction. Elevated severe storms, droughts, warming and rising oceans, species dissipation, deficient food availability, exacerbated health risks <xref ref-type="bibr" rid="ridm1841899932">31</xref>, poverty and   displacement, and extreme hydrological events, such as floods and droughts, elevate the risk of water disasters, which constitute resultant preponderant challenges and issues for human survival <xref ref-type="bibr" rid="ridm1841860996">47</xref>.     Frequency analysis is pertinent in the design and modelling of hydrological systems but is frequently statistically restricted by the entire spatiotemporal observation <xref ref-type="bibr" rid="ridm1841804468">48</xref>.  Universally, climate change    pertains to the long-run invariant alterations of temperature trajectories and weather presentations from seasonal averages. Climate change exerts an expansive impact on global technology due to a warmer climate culminating in arduous morbidity and mortality <xref ref-type="bibr" rid="ridm1841802164">49</xref> from risks, such as extreme hydrologic events, heat, diarrhea, malaria, emerging and reemerging infectious diseases as demonstrated on the clinicopathologic and healthcare spectra. Hazard risk management and adaptation strategies need to be conceived on spatiotemporal analysis of inter alia trends and future climate change and extreme hydrologic events in biodiversity, environment and health including projections and predictability of disaster risk reduction. </p>
      <p>In essence, preservation and safeguarding of biodiversity, environment, improved development, prevention and eradication of prevalent and endemic diseases and disabilities, including reduction in both severe and moderate malnutrition are essential for human welfare and well-being. The health of vulnerable persons, elderly or aged individuals <xref ref-type="bibr" rid="ridm1841797556">50</xref>, women and children reflects the general health of the population. Simultaneously, the environmental climate dictates the socio-economic and health   status or indices as well as the living conditions of the inhabitants <xref ref-type="bibr" rid="ridm1841794892">51</xref>. Numeral factors must be     critically acclaimed in the reduction of risks to biodiversity, environment and health from extreme   hydrological events and climate change. These factors are associated with convergence in land use planning, adaptation and mitigation modalities, as well as elucidation of social determinants of health, exposure, vulnerability and adaptive capacity within defined or specific populations and cultures <xref ref-type="bibr" rid="ridm1841848684">41</xref><xref ref-type="bibr" rid="ridm1841844940">42</xref>. The adverse impacts on human health due to climate change are expansively more appreciated or evidenced in   urban precincts, with invariable and deferred pathways. An integrated systemic strategy to obviate health risks due climate change provides encompassing beneficial results for adaptation in addressing diverse health risks. Spatiotemporally, It is pertinent that each sphere of urban planning takes into cognizance aspects of policy and planning decisions as well as intricate complexity of  urban areas <xref ref-type="bibr" rid="ridm1841792156">52</xref> or conurbations. Extreme weather and climate-associated incidents infringe human health resulting in morbidity, mortality and socioeconomic problems <xref ref-type="bibr" rid="ridm1841802164">49</xref>. Climate change has altered extreme event frequency, intensity, geographic patterns, and propensity as a driver for impending change. These events include hydrological extremes and temperatures and global warming. The inextricably linked pathways to extreme events associated with health outcomes and economic loss are diverse, complex with impact on disease encumbrance. </p>
    </sec>
    <sec id="idm1842343820" sec-type="conclusions">
      <title>Conclusion </title>
      <p>Due to extreme hydrological events and climate change, it is pertinent for a holistic approach to be critically applied for risk reduction concerning vulnerabilities of health, environment and biodiversity. With reliance on adaptive capacity through training and education, economic stability and inclusive governance, there can be proper resilience to incessant disasters. The reduction of greenhouse gas   emissions, and emphasis on health spheres and disaster risk management are vital. Extreme weather and climate-associated incidents suppress human health with resultant morbidity, mortality and        socioeconomic attendant complications and consequences. </p>
    </sec>
  </body>
  <back>
    <ref-list>
      <ref id="ridm1842185788">
        <label>1.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Haines</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Ebi</surname>
            <given-names>K</given-names>
          </name>
          <article-title>The imperative for climate action to protect health</article-title>
          <date>
            <year>2019</year>
          </date>
          <source>N Engl J Med</source>
          <volume>380</volume>
          <issue>3</issue>
          <fpage>263</fpage>
          <lpage>273</lpage>
          <pub-id pub-id-type="doi">10.1056/NEJMra1807873</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842248788">
        <label>2.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Josey</surname>
            <given-names>K P</given-names>
          </name>
          <name>
            <surname>Delaney</surname>
            <given-names>S W</given-names>
          </name>
          <name>
            <surname>Wu</surname>
            <given-names>X</given-names>
          </name>
          <name>
            <surname>Nethery</surname>
            <given-names>R C</given-names>
          </name>
          <name>
            <surname>DeSouza</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Braun</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Dominici</surname>
            <given-names>F</given-names>
          </name>
          <article-title>Air pollution and mortality at the intersection of race and social class</article-title>
          <date>
            <year>2023</year>
          </date>
          <source>N Engl J Med</source>
          <volume>388</volume>
          <issue>15</issue>
          <fpage>1396</fpage>
          <lpage>1404</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842257572">
        <label>3.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Goldman</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Sommers</surname>
            <given-names>B D</given-names>
          </name>
          <article-title>Climate-Informed Patient Care as a Social Determinant of Health</article-title>
          <date>
            <year>2024</year>
          </date>
          <source>JAMA Health Forum</source>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>10</fpage>
          <lpage>1001</lpage>
          <pub-id pub-id-type="doi">10.1001/jamahealthforum.2024.0095</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842044148">
        <label>4.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Invariance of Extreme Hydrologic Events and Climate Change in the Risk Reduction on Environment and Health</article-title>
          <date>
            <year>2025</year>
          </date>
          <source>Greenfort International Journal of Applied Medical Science. DOI:</source>
          <fpage>10</fpage>
          <lpage>62046</lpage>
          <pub-id pub-id-type="doi">10.62046/gijams.2025.v03i02.011</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842042636">
        <label>5.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Exploring the repositioning of health, extreme Hydrologic events, and global change</article-title>
          <date>
            <year>2024</year>
          </date>
          <source>International Journal of Medical Research and Medical Case Reports</source>
          <volume>1</volume>
          <issue>2</issue>
        </mixed-citation>
      </ref>
      <ref id="ridm1842038676">
        <label>6.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Yenew</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Bayeh</surname>
            <given-names>G M</given-names>
          </name>
          <name>
            <surname>Gebeyehu</surname>
            <given-names>A A</given-names>
          </name>
          <article-title>Scoping review on assessing climate-sensitive health risks</article-title>
          <date>
            <year>2025</year>
          </date>
          <source>BMC Public Health</source>
          <volume>25</volume>
          <fpage>914</fpage>
          <lpage>10</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842034068">
        <label>7.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Abbas</surname>
            <given-names>H W</given-names>
          </name>
          <name>
            <surname>Guo</surname>
            <given-names>X</given-names>
          </name>
          <article-title>Climate-Related Vulnerability Assessment Toward Disaster Risk Reduction: Insight from Pakistan</article-title>
          <date>
            <year>2023</year>
          </date>
          <source>Journal of Homeland Security and Emergency Management</source>
          <volume>20</volume>
          <fpage>10</fpage>
          <lpage>1515</lpage>
          <pub-id pub-id-type="doi">10.1515/jhsem-2021-0046</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842028596">
        <label>8.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kassaye</surname>
            <given-names>S M</given-names>
          </name>
          <name>
            <surname>Tadesse</surname>
            <given-names>T</given-names>
          </name>
          <name>
            <surname>Tegegne</surname>
            <given-names>G</given-names>
          </name>
          <article-title>Quantifying the climate change impacts on the magnitude and timing of hydrological extremes in the Baro River Basin, Ethiopia. Environ Syst Res</article-title>
          <date>
            <year>2024</year>
          </date>
          <volume>13</volume>
          <fpage>10</fpage>
          <lpage>1186</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842019540">
        <label>9.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Katz</surname>
            <given-names>R W</given-names>
          </name>
          <article-title>Hydrological Extremes</article-title>
          <date>
            <year>2014</year>
          </date>
          <chapter-title>In book:</chapter-title>
          <fpage>10</fpage>
          <lpage>1002</lpage>
          <publisher-loc>DOI:</publisher-loc>
          <pub-id pub-id-type="doi">10.1002/9781118445112.stat07712</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842023572">
        <label>10.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Bolan</surname><given-names>S</given-names></name><name><surname>Padhye</surname><given-names>L P</given-names></name><name><surname>Jasemizad</surname><given-names>T</given-names></name><name><surname>Govarthanan</surname><given-names>M</given-names></name><name><surname>Karmegam</surname><given-names>N</given-names></name><name><surname>Wijesekara</surname><given-names>H</given-names></name><name><surname>Amarasiri</surname><given-names>D</given-names></name><name><surname>Hou</surname><given-names>D</given-names></name><name><surname>Zhou</surname><given-names>P</given-names></name><article-title>Impacts of climate change on the fate of contaminants through extreme weather events, Science of The Total Environment. Volume 909</article-title><date><year>2024</year></date>
https://doi.org/10.1016/j.scitotenv.2023.168388



</mixed-citation>
      </ref>
      <ref id="ridm1842000180">
        <label>11.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Environmental impact assessment, land degradation and remediation in Nigeria: current problems and implications for future global change in agricultural and mining areas</article-title>
          <date>
            <year>2011</year>
          </date>
          <source>International Journal of Sustainable Development &amp; World Ecology</source>
          <volume>18</volume>
          <issue>1</issue>
          <fpage>36</fpage>
          <lpage>42</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841997444">
        <label>12.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Development and implementation of environmental monitoring and information systems for water resources</article-title>
          <date>
            <year>1998</year>
          </date>
          <source>Env Manage &amp; Hlth</source>
          <volume>9</volume>
          <issue>4</issue>
          <fpage>153</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1108/09566169810228908</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841994852">
        <label>13.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Environmental and social consequences of metals and mines on water</article-title>
          <date>
            <year>1998</year>
          </date>
          <source>Int J Env Studies</source>
          <volume>54</volume>
          <issue>1</issue>
          <fpage>73</fpage>
          <lpage>81</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842004788">
        <label>14.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Ecosystem cadastre of plant-soil interactions with nonferrous metals</article-title>
          <date>
            <year>2021</year>
          </date>
          <source>IJCRCPS</source>
          <volume>8</volume>
          <issue>6</issue>
          <fpage>17</fpage>
          <lpage>26</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841980204">
        <label>15.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Nguma</surname>
            <given-names>R K</given-names>
          </name>
          <name>
            <surname>Kiluva</surname>
            <given-names>V M</given-names>
          </name>
          <article-title>Management of extreme hydrological events, Editor(s): Victor Ongoma, Hossein Tabari</article-title>
          <date>
            <year>2022</year>
          </date>
          <source>Climate Impacts on Extreme Weather, Elsevier, Chapter</source>
          <volume>16</volume>
          <fpage>271</fpage>
          <lpage>286</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841976388">
        <label>16.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>The impacts of mining operations in Nigeria with particular reference to the Enyigba-Abakaliki area</article-title>
          <date>
            <year>1993</year>
          </date>
          <source>Int J Env Edu &amp; Inf</source>
          <volume>12</volume>
          <issue>4</issue>
          <fpage>321</fpage>
          <lpage>36</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841974876">
        <label>17.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>The Impacts of Non-Ferrous Metal Mining Operations: Pollution, Sustainable and Geopolitical Dimensions</article-title>
          <date>
            <year>2024</year>
          </date>
          <source>Journal of Geotechnical Studies</source>
          <volume>9</volume>
          <issue>1</issue>
          <fpage>31</fpage>
          <lpage>41</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841986900">
        <label>18.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Xiong</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Guo</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Chen</surname>
            <given-names>J Abhishek</given-names>
          </name>
          <name>
            <surname>Yin</surname>
            <given-names>J</given-names>
          </name>
          <article-title>Global evaluation of the “dry gets drier, and wet gets wetter” paradigm from a terrestrial water storage change perspective. Hydrology and Earth System Sciences</article-title>
          <date>
            <year>2022</year>
          </date>
          <volume>26</volume>
          <issue>24</issue>
          <fpage>6457</fpage>
          <lpage>6476</lpage>
          <pub-id pub-id-type="doi">10.5194/hess-26-6457-2022</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841982724">
        <label>19.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Taye</surname>
            <given-names>M T</given-names>
          </name>
          <name>
            <surname>Dyer</surname>
            <given-names>E</given-names>
          </name>
          <article-title>Hydrologic Extremes in a Changing Climate: a Review of Extremes</article-title>
          <date>
            <year>2024</year>
          </date>
          <chapter-title>in East Africa. Curr Clim Change Rep</chapter-title>
          <volume>10</volume>
          <fpage>1</fpage>
          <lpage>11</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841961068">
        <label>20.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Tabari</surname>
            <given-names>H</given-names>
          </name>
          <article-title>Climate Change Impact on Flood and Extreme Precipitation Increases with Water Availability</article-title>
          <date>
            <year>2020</year>
          </date>
          <source>Sci. Rep</source>
          <volume>10</volume>
          <fpage>13768</fpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841959124">
        <label>21.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Thackeray</surname>
            <given-names>C W</given-names>
          </name>
          <name>
            <surname>Hall</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Norris</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Chen</surname>
            <given-names>D</given-names>
          </name>
          <article-title>Constraining the Increased Frequency of Global Precipitation Extremes under Warming</article-title>
          <date>
            <year>2022</year>
          </date>
          <source>Nat. Clim. Change</source>
          <volume>12</volume>
          <fpage>441</fpage>
          <lpage>448</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841954948">
        <label>22.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kovats</surname>
            <given-names>R S</given-names>
          </name>
          <article-title>El Niño and human health</article-title>
          <date>
            <year>2000</year>
          </date>
          <source>Bull World Health Organ</source>
          <volume>78</volume>
          <issue>9</issue>
          <fpage>1127</fpage>
          <lpage>35</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841953940">
        <label>23.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Chukwuma</surname><given-names>Sr C</given-names></name><article-title>Environment and Development: Approaches to strategies for the improvement of human well-being in Abakaliki area</article-title><date><year>1994</year></date><source>Nigeria. Environmental Conservation</source><volume>21</volume><issue>4</issue><fpage>359</fpage><lpage>61</lpage>
https://www.jstor.org/stable/44519013. https://doi.org/10.1017/S0376892900033695



</mixed-citation>
      </ref>
      <ref id="ridm1841951060">
        <label>24.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Latent constraints for improved environmental health management in non-industrialised countries</article-title>
          <date>
            <year>1995</year>
          </date>
          <source>Env Manage &amp; Hlth</source>
          <volume>6</volume>
          <issue>4</issue>
          <fpage>9</fpage>
          <lpage>14</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841930060">
        <label>25.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Compson</surname><given-names>Z G</given-names></name><name><surname>Monk</surname><given-names>W A</given-names></name><name><surname>Sarremejane</surname><given-names>R</given-names></name><name><surname>DelVecchia</surname><given-names>A G</given-names></name><name><surname>Burrows</surname><given-names>R M</given-names></name><name><surname>Gao</surname><given-names>S</given-names></name><name><surname>Ruddell</surname><given-names>B L</given-names></name><name><surname>Hong</surname><given-names>Y</given-names></name><name><surname>Allen</surname><given-names>D C</given-names></name><article-title>Dryland Rivers and Streams. Editor(s): Thomas Mehner, Klement Tockner</article-title><date><year>2022</year></date><source>Encyclopedia of Inland Waters (Second Edition), Elsevier</source><fpage>616</fpage><lpage>627</lpage>
https://doi.org/10.1016/B978-0-12-819166-8.00156-0. https://www.sciencedirect.com/science/article/pii/B9780128191668001560



</mixed-citation>
      </ref>
      <ref id="ridm1841926460">
        <label>26.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>McIntosh</surname>
            <given-names>A R</given-names>
          </name>
          <name>
            <surname>Leigh</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Boersma</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>García-Berthou</surname>
            <given-names>E</given-names>
          </name>
          <article-title>Food Webs and Trophic Interactions in Intermittent Rivers and Ephemeral Streams. In book: Intermittent Rivers and Ephemeral Streams</article-title>
          <date>
            <year>2017</year>
          </date>
          <fpage>10</fpage>
          <lpage>1016</lpage>
          <pub-id pub-id-type="doi">10.1016/B978-0-12-803835-2.00012-7</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841923220">
        <label>27.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Bunn</surname>
            <given-names>S E</given-names>
          </name>
          <name>
            <surname>Thoms</surname>
            <given-names>M C</given-names>
          </name>
          <name>
            <surname>Hamilton</surname>
            <given-names>S K</given-names>
          </name>
          <name>
            <surname>Capon</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Flow variability in dryland rivers: Boom, bust and the bits in between. River Research and Applications</article-title>
          <date>
            <year>2006</year>
          </date>
          <volume>22</volume>
          <issue>2</issue>
          <fpage>10</fpage>
          <lpage>1002</lpage>
          <publisher-name>SourceOAI</publisher-name>
          <pub-id pub-id-type="doi">10.1002/rra.904</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841934668">
        <label>28.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Serrano</surname>
            <given-names>M A</given-names>
          </name>
          <name>
            <surname>Boguñá</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Vespignani</surname>
            <given-names>A</given-names>
          </name>
          <article-title>Extracting the Multiscale Backbone of Complex Weighted Networks</article-title>
          <date>
            <year>2009</year>
          </date>
          <chapter-title>Proceedings of the National Academy of Sciences</chapter-title>
          <volume>106</volume>
          <issue>16</issue>
          <fpage>6483</fpage>
          <lpage>8</lpage>
          <pub-id pub-id-type="doi">10.1073/pnas.0808904106</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841903892">
        <label>29.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Contamination of soils and rice by heavy metals in the Enyigba-Abakaliki lead and zinc mine</article-title>
          <date>
            <year>1994</year>
          </date>
          <source>Nigeria. Toxicol &amp; Environ Chem</source>
          <volume>41</volume>
          <fpage>125</fpage>
          <lpage>30</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841902236">
        <label>30.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Hasanuzzaman</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Masayuki</surname>
            <given-names>F M</given-names>
          </name>
          <name>
            <surname>Biswas</surname>
            <given-names>J K</given-names>
          </name>
          <date>
            <year>2019</year>
          </date>
          <chapter-title>Advances in Rice Research for Abiotic Stress Tolerance. Book. Edited by: Hasanuzzaman</chapter-title>
        </mixed-citation>
      </ref>
      <ref id="ridm1841899932">
        <label>31.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>MKK</surname>
            <given-names>Rony</given-names>
          </name>
          <name>
            <surname>Wahiduzzaman</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>M</surname>
            <given-names/>
          </name>
          <article-title>Impact of El Niño on public health and its preparedness measures</article-title>
          <date>
            <year>2024</year>
          </date>
          <source>Bull Natl Res Cent</source>
          <volume>48</volume>
          <fpage>10</fpage>
          <lpage>1186</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841893668">
        <label>32.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Rocha</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Oliveira</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Viana</surname>
            <given-names>C M</given-names>
          </name>
          <name>
            <surname>Ribeiro</surname>
            <given-names>A I</given-names>
          </name>
          <article-title>Chapter 8 - Climate change and its impacts on health, environment and</article-title>
          <date>
            <year>2022</year>
          </date>
          <fpage>253</fpage>
          <lpage>279</lpage>
          <publisher-name>Academic Press</publisher-name>
        </mixed-citation>
      </ref>
      <ref id="ridm1841890860">
        <label>33.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Perspectives in the emergence and re-emergence of infectious diseases, geopolitics and gain-of-function research. Scholars international journal of biochemistry</article-title>
          <date>
            <year>2022</year>
          </date>
          <fpage>10</fpage>
          <lpage>36348</lpage>
          <publisher-loc>DOI:</publisher-loc>
          <pub-id pub-id-type="doi">10.36348/sijb.2022.v05i01.001</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841887692">
        <label>34.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Whither the Trends, Innovations and Expertise of the New Public Administration</article-title>
          <date>
            <year>2024</year>
          </date>
          <chapter-title>Innovation in Economy &amp; Policy Research. MAT Journals</chapter-title>
          <volume>5</volume>
          <issue>1</issue>
          <fpage>7</fpage>
          <lpage>16</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841884308">
        <label>35.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>A</surname>
            <given-names>De Vita</given-names>
          </name>
          <name>
            <surname>Belmusto</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>F</surname>
            <given-names>Di Perna</given-names>
          </name>
          <name>
            <surname>Tremamunno</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>G</surname>
            <given-names>De Matteis</given-names>
          </name>
          <name>
            <surname>Franceschi</surname>
            <given-names>F</given-names>
          </name>
          <name>
            <surname>Covino</surname>
            <given-names>M</given-names>
          </name>
          <chapter-title>on behalf of the CLIMPS Group. (2024) The Impact of Climate Change and Extreme Weather Conditions on Cardiovascular Health and Acute Cardiovascular Diseases. Editors: Nathan Wong, Rita Pavasini. Clin Med</chapter-title>
          <volume>13</volume>
          <issue>3</issue>
          <fpage>759</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.3390/jcm13030759</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841881644">
        <label>36.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Awuni</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Adarkwah</surname>
            <given-names>F</given-names>
          </name>
          <name>
            <surname>Ofori</surname>
            <given-names>B D</given-names>
          </name>
          <name>
            <surname>Purwestri</surname>
            <given-names>R C</given-names>
          </name>
          <name>
            <surname>DCH</surname>
            <given-names>Bernal</given-names>
          </name>
          <name>
            <surname>Hajek</surname>
            <given-names>M</given-names>
          </name>
          <article-title>Managing the challenges of climate change mitigation and adaptation strategies in Ghana</article-title>
          <date>
            <year>2023</year>
          </date>
          <source>Heliyon</source>
          <volume>9</volume>
          <issue>5</issue>
          <fpage>10</fpage>
          <lpage>1016</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841875380">
        <label>37.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Abrignani</surname>
            <given-names>M G</given-names>
          </name>
          <name>
            <surname>Lombardo</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Braschi</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Renda</surname>
            <given-names>N</given-names>
          </name>
          <name>
            <surname>Abrignani</surname>
            <given-names>V</given-names>
          </name>
          <article-title>Climatic influences on cardiovascular diseases</article-title>
          <date>
            <year>2022</year>
          </date>
          <source>World J Cardiol</source>
          <volume>14</volume>
          <issue>3</issue>
          <fpage>152</fpage>
          <lpage>169</lpage>
          <pub-id pub-id-type="doi">10.4330/wjc.v14.i3.152</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841857180">
        <label>38.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Syndemics of chronic and acute diseases in vulnerable populations</article-title>
          <date>
            <year>2017</year>
          </date>
          <source>Acta Medica Scientia</source>
          <volume>04</volume>
          <issue>01</issue>
          <fpage>www.asdpub.com/index.php/ams.</fpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841853868">
        <label>39.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Nigeria</surname>
            <given-names/>
          </name>
          <article-title>Climate Change and Health</article-title>
          <date>
            <year>2024</year>
          </date>
          <chapter-title>National Vulnerability and Adaptation</chapter-title>
        </mixed-citation>
      </ref>
      <ref id="ridm1841851204">
        <label>40.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Ma</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Li</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Chen</surname>
            <given-names>X</given-names>
          </name>
          <name>
            <surname>Xu</surname>
            <given-names>J</given-names>
          </name>
          <date>
            <year>2025</year>
          </date>
          <chapter-title>Extreme Temperatures Promote High-Fat Diets. medRxiv. 2025; 04(08):</chapter-title>
          <fpage>25325375</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.1101/2025.04.08.25325375</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841848684">
        <label>41.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Ebi</surname>
            <given-names>K L</given-names>
          </name>
          <name>
            <surname>Vanos</surname>
            <given-names>J K</given-names>
          </name>
          <name>
            <surname>JW</surname>
            <given-names>Jane W Baldwin</given-names>
          </name>
          <article-title>Extreme Weather and Climate Change: Population Health and Health System Implications. Annual Review of Public Health</article-title>
          <date>
            <year>2021</year>
          </date>
          <volume>42</volume>
          <issue>1</issue>
          <fpage>10</fpage>
          <lpage>1146</lpage>
          <pub-id pub-id-type="doi">10.1146/annurev-publhealth-012420-105026</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841844940">
        <label>42.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>C</surname>
            <given-names/>
          </name>
          <article-title>Monitoring trends and determinants of type 1 diabetes in geographically-determined populations</article-title>
          <date>
            <year>2023</year>
          </date>
          <source>Clinical Research Communications</source>
          <volume>6</volume>
          <issue>1</issue>
          <pub-id pub-id-type="doi">10.53388/CRC2023003</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841839828">
        <label>43.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Pelke</surname>
            <given-names>Sr RA</given-names>
          </name>
          <article-title>Climate Vulnerability Understanding and Addressing Threats to Essential Resources. 1st Edition -Editor: Roger A. Pielke Sr</article-title>
          <date>
            <year>2013</year>
          </date>
          <volume>9</volume>
        </mixed-citation>
      </ref>
      <ref id="ridm1841837884">
        <label>44.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Geopolitics of the nature and crises of the environment, economics and health in a sustainable society for human progress and survival</article-title>
          <date>
            <year>2024</year>
          </date>
          <source>Journal of Scientific and Innovative Research</source>
          <volume>13</volume>
          <issue>1</issue>
          <fpage>16</fpage>
          <lpage>21</lpage>
          <pub-id pub-id-type="doi">10.31254/jsir.2024.13103</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841835364">
        <label>45.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Gain-of-Function Research and Geopolitics in the Emergence and Reemergence of Infectious Diseases and Microbiome Variants</article-title>
          <date>
            <year>2021</year>
          </date>
          <source>International Journal of Chemical and Life Sciences</source>
          <volume>10</volume>
          <issue>8</issue>
          <fpage>2197</fpage>
          <lpage>2205</lpage>
          <pub-id pub-id-type="doi">10.2.1746/ijcls.2021.10.8.2</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841864524">
        <label>46.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Human hepatocytes response to pathological shifts in liver fibrosis</article-title>
          <date>
            <year>2024</year>
          </date>
          <source>The Journal of Medical Research</source>
          <volume>10</volume>
          <issue>1</issue>
          <fpage>37</fpage>
          <lpage>41</lpage>
          <pub-id pub-id-type="doi">10.31254/jmr.2024.10108</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841860996">
        <label>47.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Sillmann</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Thorarinsdottir</surname>
            <given-names>T</given-names>
          </name>
          <name>
            <surname>Keenlyside</surname>
            <given-names>N</given-names>
          </name>
          <article-title>Understanding, modeling and predicting weather and climate extremes: challenges and opportunities</article-title>
          <date>
            <year>2017</year>
          </date>
          <chapter-title>Weather and Climate Extremes.18:</chapter-title>
          <fpage>65</fpage>
          <lpage>74</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841804468">
        <label>48.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Andersen</surname>
            <given-names>C B</given-names>
          </name>
          <name>
            <surname>Wright</surname>
            <given-names>D B</given-names>
          </name>
          <name>
            <surname>Thorndahl</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Sub-Hourly to Daily Rainfall Intensity-Duration-Frequency Estimation Using Stochastic Storm Transposition and Discontinuous Radar Data</article-title>
          <date>
            <year>2022</year>
          </date>
          <source>Water</source>
          <volume>14</volume>
          <issue>24</issue>
          <fpage>4013</fpage>
          <lpage>10</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841802164">
        <label>49.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Bell</surname>
            <given-names>J E</given-names>
          </name>
          <name>
            <surname>Brown</surname>
            <given-names>C L</given-names>
          </name>
          <name>
            <surname>Conlon</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Herring</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Kunkel</surname>
            <given-names>K E</given-names>
          </name>
          <name>
            <surname>Lawrimore</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Uejio</surname>
            <given-names>C</given-names>
          </name>
          <article-title>Changes in extreme events and the potential impacts on human health</article-title>
          <date>
            <year>2018</year>
          </date>
          <source>Journal of the Air &amp; Waste Management Association</source>
          <volume>68</volume>
          <issue>4</issue>
          <fpage>265</fpage>
          <lpage>287</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841797556">
        <label>50.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Ageing, Cellular Senescence, and Diabetes, Exploring the Connections Between these Processes and their Implications for Treatment and Management</article-title>
          <date>
            <year>2025</year>
          </date>
          <source>Journal of Clinical &amp; Biomedical Research</source>
          <volume>7</volume>
          <issue>2</issue>
          <fpage>1</fpage>
          <lpage>5</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841794892">
        <label>51.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chukwuma</surname>
            <given-names>Sr C</given-names>
          </name>
          <article-title>Social welfare and population dynamics in Egypt, with particular reference to the status of women. Environmental Education and Information</article-title>
          <date>
            <year>1995</year>
          </date>
          <volume>14</volume>
          <issue>1</issue>
          <fpage>45</fpage>
          <lpage>62</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841792156">
        <label>52.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Jurgilevich</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Käyhkö</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Räsänen</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Saara</surname>
            <given-names>Pörsti S</given-names>
          </name>
          <name>
            <surname>Lagström</surname>
            <given-names>H</given-names>
          </name>
          <name>
            <surname>Käyhkö</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Juhola</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Factors influencing vulnerability to climate change-related health impacts in cities – A conceptual framework</article-title>
          <date>
            <year>2023</year>
          </date>
          <source>Environment International. Volume</source>
          <volume>173</volume>
          <fpage>10</fpage>
          <lpage>1016</lpage>
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
