<?xml version="1.0" encoding="utf8"?>
 <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd"> <article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="review-article" dtd-version="1.0" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JARH</journal-id>
      <journal-title-group>
        <journal-title>Journal of Aging Research And Healthcare</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2474-7785</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.14302/issn.2474-7785.jarh-21-4041</article-id>
      <article-id pub-id-type="publisher-id">JARH-21-4041</article-id>
      <article-categories>
        <subj-group>
          <subject>review-article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Fear of Falls and Frailty: Cause or Consequence or Both?</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Ray</surname>
            <given-names>Marks</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842150020">1</xref>
          <xref ref-type="aff" rid="idm1842148580">*</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842150020">
        <label>1</label>
        <addr-line>Department of Health and Behavior Studies, Teachers College, Columbia University, New York, NY 10027, USA.</addr-line>
      </aff>
      <aff id="idm1842148580">
        <label>*</label>
        <addr-line>Corresponding author</addr-line>
      </aff>
      <author-notes>
        <corresp>
    
    Ray Marks, <addr-line>Department of Health and Behavior Studies, Teachers College, Columbia University, New York, NY 10027, USA</addr-line><email>rm226@tc.columbia.edu</email></corresp>
        <fn fn-type="conflict" id="idm1842792404">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2021-12-16">
        <day>16</day>
        <month>12</month>
        <year>2021</year>
      </pub-date>
      <volume>4</volume>
      <issue>2</issue>
      <fpage>1</fpage>
      <lpage>13</lpage>
      <history>
        <date date-type="received">
          <day>12</day>
          <month>12</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>13</day>
          <month>12</month>
          <year>2021</year>
        </date>
        <date date-type="online">
          <day>16</day>
          <month>12</month>
          <year>2021</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2021</copyright-year>
        <copyright-holder>Ray Marks</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org/jarh/article/1743">This article is available from http://openaccesspub.org/jarh/article/1743</self-uri>
      <abstract>
        <sec id="idm1842017812">
          <title>Background</title>
          <p>Many older adults are vulnerable to               becoming frail. They are also often at risk for              falling and serious injuries and poor health                     outcomes.</p>
        </sec>
        <sec id="idm1842017884">
          <title>Aim</title>
          <p>This exploratory review examines the      correlates of frailty, and fear of falling and their association insofar as older adults wellbeing may be jeopardized.   </p>
          <p> </p>
        </sec>
        <sec id="idm1842017524">
          <title>Methods and Procedures</title>
          <p>Articles extracted from major electronic data bases that addressed the current topic of interest were used. Key findings regarding the syndromes of frailty and fear of falling were duly downloaded, analyzed and summarized in narrative form.  </p>
        </sec>
        <sec id="idm1842018532">
          <title>Results</title>
          <p>A high proportion of older adults can be              expected to exhibit frailty or become frail as they age. Many too are at risk for falls and fear of future falls, regardless of frailty status. A persistent fear of falls may however, heighten frailty risk or manifestations if not duly addressed in a timely manner.</p>
        </sec>
        <sec id="idm1842016444">
          <title>Conclusion</title>
          <p>Prompt comprehensive assessment of at risk older adults, as well as the frail and pre frail older adult, plus those who have fallen may avert serious injury and long term disability plus excess frailty and its deleterious impacts this syndrome has on aging older adults as well as societies.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>Aging</kwd>
        <kwd>Elderly</kwd>
        <kwd>Falls</kwd>
        <kwd>Fear of Falling</kwd>
        <kwd>Frailty</kwd>
        <kwd>Fractures</kwd>
        <kwd>Intervention</kwd>
        <kwd>Prevention</kwd>
      </kwd-group>
      <counts>
        <fig-count count="2"/>
        <table-count count="1"/>
        <page-count count="13"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1842018604" sec-type="intro">
      <title>Introduction </title>
      <p>Aging, a generally accepted biological                 phenomenon implicating an inevitable declining state of organ and tissue homeostasis is frequently              associated with a variety of chronic health conditions,   anxiety, depression, various fears, the use of multiple pharmaceutical drugs, nutritional challenges, and multiple physical limitations. Also often associated with various degrees of frailty or a tendency to become frail, this state of increased vulnerability to stress is a potentially                    preventable critical aging intermediate found to markedly increase the extent of age-associated physical, cognitive, and psychosocial challenges, as well as accelerating                overall declines in well being <xref ref-type="bibr" rid="ridm1842050324">1</xref><xref ref-type="bibr" rid="ridm1842118580">2</xref>. However, even though frailty is a condition expected to increase in prevalence in future years <xref ref-type="bibr" rid="ridm1842123404">3</xref>, and may predict dementia <xref ref-type="bibr" rid="ridm1842118580">2</xref>, the                 possible determinants of frailty attributable to factors   other than age and nutrition, such as a high degree of              cognitive challenges including the fear of falling-or a lack of confidence in one’s ability to safely undertake active mobility movements, which may heighten frailty, are not well articulated in the mainstream literature. This is               despite the possibility that fears evoked by the experience or envisioned experience of falling may represent an               important albeit overlooked frailty mediator, and one that is potentially preventable or amenable to modification and to thereby potentially mitigating a variety of cumulative adverse frailty consequences, as well as its onset and              exacerbation among older vulnerable adults. </p>
      <p>Given the growing need for health providers and others to assist older adults to avoid preventable illnesses or disability states, as well as an excess aging burden and low life quality, and to enable them to age more                successfully than not, it appears there may indeed be some merit to examining those factors other than                   mainstream frailty determinants, as well as falls                       determinants that may lead to actual fears-a pervasive and serious problem among the elderly <xref ref-type="bibr" rid="ridm1841915484">4</xref> associated with a decreased ability to function physically, decreased                       mobility, muscle weakness, gait disturbances, falls, and a resultant vulnerability to a heightened frailty state <xref ref-type="bibr" rid="ridm1841899028">5</xref>. In particular, and in light of the severe impact of frailty on all the aforementioned factors, more knowledge in this                 regard not only appears warranted, but could arguably help to mitigate the rate and degree of downward                      spiraling of the older adults’ health as well as their frailty status- and in turn, may have immense health implications for both the aging adult, as well as society. </p>
      <p>In this regard, this mini review elected to                   selectively focus on establishing if there is some evidence to support the view that fear of falling can independently or collectively along with other aging features foster                   frailty, which in turn can predictably engender a high rate of falling related fears and significant injuries and adverse health outcomes.</p>
      <p>Indeed, this idea, although possibly not novel, may yet prove to have considerable far reaching value insofar as prevention of either of these two states is concerned, if we consider these factors alone may not only jeopardize overall health, longevity, and life quality, but foster a high risk for injuries such as hip fractures, expected to show an immense increase in prevalence among the elderly by 2050. </p>
    </sec>
    <sec id="idm1842015580">
      <title>Aim</title>
      <p>In light of the importance of helping older adults to maintain a high level of wellness and one free from                excess fears and preventable health issues, this mini                 review sought to establish whether there is a role for              improvements in frailty prevention and its possible link to excess fears of falling among older adult populations.</p>
      <p>A parallel aim was not only to establish if more should be done in this regard, but if desirable, in what       respect? </p>
      <sec id="idm1842014212">
        <title>Hypothesis </title>
        <p>It was hypothesized that a possible bidirectional relationship would be found to exist between frailty and fears of falling among a substantive proportion of older community dwelling adults. Moreover, a link for both  frailty and falls fears to hip fracture risk would appear to be an apparent, albeit possibly preventable, important disabling pathway.</p>
        <p> </p>
      </sec>
      <sec id="idm1842015292">
        <title>Relevance</title>
        <p>Frailty, a potentially preventable serious health state and undisputed impediment to well-being among many older populations, not only impacts bone fragility, but overall energy levels, muscle strength capacity, and gait. Frailty also commonly engenders various degrees of anxiety,  and depression <xref ref-type="bibr" rid="ridm1841894348">6</xref> that alone or in combination with one or more of these factors can be expected to not only exacerbate frailty, but also associated levels of                 serious morbidity and excess rates of premature                      mortality, as well as possible parallel increases in falls risk, as well as fears of falling. </p>
        <p>As such, the excess human as well as fiscal costs of frailty are currently immeasurable, and are likely to             increase, rather than decrease, as societies age unless              actions are taken to offset this possible cycle of highly    adverse events. In particular, falls that often cause severe injury, anxiety and loss of confidence, as well as activity avoidance, depression, and social isolation due to ‘fears of falling’ a collective term denoting a set of negative beliefs that appears to occur in up to 85 percent of older adults who have experienced prior falls <xref ref-type="bibr" rid="ridm1841888004">7</xref> undoubtedly tends to increase frailty or provoke its multiple manifestations <xref ref-type="bibr" rid="ridm1841877404">8</xref>. In particular, falls leading to hip fractures that occur               frequently among the frail elderly not only predict less than desirable outcomes of survivors post hip fracture surgery <xref ref-type="bibr" rid="ridm1841872436">9</xref>, but the persistence of falls fears, anxiety, and low self-efficacy <xref ref-type="bibr" rid="ridm1841868332">10</xref>.</p>
      </sec>
      <sec id="idm1842016228">
        <title>Rationale</title>
        <p>Frailty, an age associated syndrome commonly attributed to under nutrition among other factors, appears strongly associated with a progressive decline in several physiological systems that can collectively heighten the older adult’s vulnerability to the risk of multiple adverse health events and outcomes, such as disability or                     death <xref ref-type="bibr" rid="ridm1841880644">11</xref>. In this regard, both frailty itself, as well as falls injuries often attributable in part to frailty features such as muscle and bone mass declines, and which often produce an excess of fears, such as falls related fears, can clearly be expected to lower the ability of the affected frail aging adult to adapt to one or more undesirable stresses as well as reducing the chances of successful aging and a high life of quality. Yet, for many older adults living in the                       community and who may slowly lose their independence, this remains an enormous personal problem, and is one clearly likely to markedly raise the immense and profound social costs associated its well established negative impact on function, as well as social and mental health                       status <xref ref-type="bibr" rid="ridm1841853972">12</xref><xref ref-type="bibr" rid="ridm1841849004">13</xref>, particularly if it contributes to a fragility hip fracture <xref ref-type="bibr" rid="ridm1841880644">11</xref>. In turn, as well as fostering an increased risk for falling or actual fall injuries leading to a fear of falling, fractures and further possible injuries and frailty or the onset of frailty, a deleterious perpetual cycle of               adverse health outcomes can be expected to ensue. In this regard, although Malini et al. <xref ref-type="bibr" rid="ridm1841849004">13</xref> found fear of falling in older adults to occur at high rates in this population,                Malini et al. who found use of seven or more medications, having a hearing impairment, being functionally                       dependent in activities of daily living, diminished walking speed, fair and poor/very poor self-rated health and               depressive symptoms to be key related health issues, did not discuss the factor of frailty directly in this respect. However, Crehan et al. <xref ref-type="bibr" rid="ridm1841848572">14</xref>  found a quarter of 47 elderly fallers who appeared to exhibit falls fears were also largely frail (75% cases), while in a study of older adults located in four Indian villages, among several associated factors mentioned as salient frailty determinants, such as low     education, socioeconomic status and physical activity, age, being female, the frail elderly observed in that study               tended to have a higher odds of falls as well as fear of     falling compared to those designated as being non-frail, irrespective of the frailty definition <xref ref-type="bibr" rid="ridm1841842380">15</xref>.  As well as falls, various fear perceptions, which have been studied for some time have shown the specific ‘fear of falling’ may in turn lead to the onset or perpetuation of a state of frailty, poor life quality, and a heightened falls risk and incidence of falls in their own right <xref ref-type="bibr" rid="ridm1841826404">16</xref>. Indeed, a fear of falling and/or low falls efficacy appears to be a key risk factor for      frailty in older adults with and without diabetes <xref ref-type="bibr" rid="ridm1841822300">17</xref>, and is one suggesting this linkage may have a possible                    profound role to play in terms of clarifying those frailty determinants that might be modifiable, and their role should not be negated, but rather, should arguably be     studied further in the future as indicated by                              Seematter-Bagnoud et al. <xref ref-type="bibr" rid="ridm1841816540">18</xref>.</p>
      </sec>
    </sec>
    <sec id="idm1842014644" sec-type="methods">
      <title>Methods and Procedures</title>
      <p>In accord with the aims of this report, the                    PUBMED, PUBMED CENTRAL, and GOOGLE SCHOLAR   depositaries believed to house salient topical peer                   reviewed articles were carefully searched. Key terms used alone or in combination included, ‘aging’, ‘frailty’, ‘frail elderly’, ‘fear of falling’, ‘interventions’. No yearly                      restrictions were applied, and after an extensive scan of the available data, all pertinent reports addressing the current topic were scrutinized in detail, regardless of              research design, and those deemed of substantive                   relevance were selected to provide an overview of this topic. The method of reporting in this instance was limited solely to a narrative descriptive format, given the low numbers of topical papers, or any substantive numbers of prospective studies on this topic. Excluded were foreign articles, proposals for future studies, nursing home                  studies, and issues related to frailty other than falls fears.</p>
    </sec>
    <sec id="idm1842015940">
      <title>Search Results  </title>
      <p>The study of frailty has been pursued for more than four decades and as representative of the sub study topics covered, the inventory posted at PUBMED                       1980-2021 and downloaded December 10, 2021 revealed a very modest number of articles linking frailty and falling fears as follows.</p>
      <p>Among these, more than half were not relevant to the present discourse<italic>,</italic> or were study proposals. Those that were deemed relevant were categorized as being of                  general reports, versus research based reports. </p>
      <sec id="idm1842013420">
        <title>General Observations </title>
        <p>Among the articles relevant to the present topic, although limited in quantity, available data do appear to strongly support the view that many older adults are likely to be frail or in a pre frailty state, a recently constructed term and syndrome employed to characterize those                   vulnerable older adults who tend to exhibit an increased risk of premature or excess rates of functional declines, institutionalization, hospitalization, and death <xref ref-type="bibr" rid="ridm1842050324">1</xref><xref ref-type="bibr" rid="ridm1841811284">19</xref>.                    Other reports indicate that those older adults deemed to be frail, as well as those elderly who are deemed in robust health may yet both exhibit high rates of falling and                  possible subsequent fears of falling if they have incurred a an injurious fall or believe they are at risk for a future fall. Conceptually, this appears to set the stage for either                 magnifying the presence of or increasing its risk. In                particular, those elderly who restrict their weight bearing activities and others out of falling fears and who may then inadvertently suffer excess muscle mass losses, bone                 mineral density alterations, weakness and lack of energy, depression, and a heightened medication need, among other negative frailty associated impacts may be highly vulnerable in this regard. Those who have studied this    topic thus tend to agree that this series of overlapping events is undoubtedly of high importance to acknowledge in that once a cycle of falls and frailty is established, this situation can be expected to foster a high risk state for         serious injuries, adverse health outcomes including            falls <xref ref-type="bibr" rid="ridm1842123404">3</xref>, as well as possible subsequent increments in      frailty <xref ref-type="bibr" rid="ridm1841791596">20</xref>, wherein there may be a further and more              permanent loss of the well attuned harmonic interaction between multiple domains or dimensions of wellbeing including those of multiple genetic, biological, functional, cognitive, psychological and functional health                             domains <xref ref-type="bibr" rid="ridm1841786124">21</xref>. </p>
        <p>In light of these highly negatively impactful events, including possible increases in hospitalizations, immense health care costs, and premature mortality                rates <xref ref-type="bibr" rid="ridm1842123404">3</xref>, and the belief that neither  frailty nor falls are inevitable, a fair number of current recommendations to offset this adverse cycle of events have been documented. These include the application of early screening as well as efforts to actively intervene to avert this negative cycle of interacting events as well as its various secondary health outcomes and cycle of excess suffering, including                comorbidity and falls <xref ref-type="bibr" rid="ridm1841786124">21</xref><xref ref-type="bibr" rid="ridm1841797644">22</xref>.</p>
      </sec>
      <sec id="idm1842012340">
        <title>What the Research Shows</title>
        <p><italic>​</italic>Although frailty is often associated with                      functional declines, and is said to be distinguishable from aging and to confer a high risk for falls <xref ref-type="bibr" rid="ridm1841797644">22</xref><xref ref-type="bibr" rid="ridm1841760068">23</xref>, many studies of older adults currently reviewed, such as that by Tomita et al. <xref ref-type="bibr" rid="ridm1841757044">24</xref>, Makino et al. <xref ref-type="bibr" rid="ridm1841750348">25</xref> and Lach et al. <xref ref-type="bibr" rid="ridm1841745236">26</xref>, did not discuss the attribute of frailty as a possible falls fear predictor in community dwelling elderly adults. In addition, the attribute termed ‘fears of falling’ also closely related to the risk as well as actual prevalence of falls among the elderly, was not mentioned in the context of a study focusing on frailty (eg., 27) As observed by Guedes et al. <xref ref-type="bibr" rid="ridm1841797644">22</xref>, Esbri-Victor et al. <xref ref-type="bibr" rid="ridm1841734940">28</xref> who did assess the               association between the attributes of fear of falling and frailty among 183 older Spanish adults with a prior falls history using validated questionnaires the authors found fears of falling to preside in over 76 percent of cases, with 55 percent indicating a high concern. Just over 88 percent of those deemed frail indicated they had a fear of falling with a relative risk of 3.18 compared to those who were not frail. Significant predictors after controlling for other variables were female gender and the presence of                   depression. Since this was a cross-sectional study, the cause-effect association between frailty and falls fears could not be established, however. </p>
        <p>Nonetheless, work conducted in 1994 –did appear to open the door to the possibility that fear of falling,              commonly generated in response to an actual fall, could possibly induce or heighten frailty, especially among those in the higher age ranges where falls related fears appear to rise incrementally <xref ref-type="bibr" rid="ridm1841763092">29</xref>. Again, this study, albeit a             cross-sectional one, did tend to support the view that             older community dwelling adults who feel depressed or dissatisfied with life, as well as those who experience falls, are likely to be more impacted as far as future falls risk and frailty are concerned <xref ref-type="bibr" rid="ridm1841826404">16</xref>. In addition, Ní Mhaoláin et al. <xref ref-type="bibr" rid="ridm1841729564">30</xref> found frail fallers to suffer from an increased fear of falling when compared to the more robust faller                    (p &lt; 0.001). Frail fallers also exhibited higher depression scores than non frail fallers, while fallers at a transitional level of frailty were deemed to represent a particularly vulnerable group psychologically speaking.</p>
        <p>Delbaere et al. <xref ref-type="bibr" rid="ridm1841725676">31</xref> who did conduct a prospective study of older adults from the perspective of falls fears, fears of movement and physical activity, and falling, was able to conclude that fear of falling had possible                    implications for the development of physical frailty, even though they did not actually assess frailty. They further affirmed those who were female and in the higher age groups were likely to be at most risk. </p>
        <p>In their study, Silviera et al.  <xref ref-type="bibr" rid="ridm1841719844">32</xref>, examining            elderly fallers with varying frailty designations, found higher fear of falling perceptions in those deemed frail compared to those deemed non frail. As well, Kressig                 et al. <xref ref-type="bibr" rid="ridm1841715812">33</xref> who noted symptoms of activity related fears of falling to be present among at least 50 percent of older adults deemed to be transitioning to frailty, also found these fears to be associated with depression, as well as prevailing levels of functional ability. Silviera et al. <xref ref-type="bibr" rid="ridm1841719844">32</xref> further concluded that frailty is indeed often associated with a heightened fear of falling, as well as reduced muscle strength, and gait abnormalities deemed to possibly lead to falls, while Makino et al. <xref ref-type="bibr" rid="ridm1841711852">34</xref> likewise conclude that frailty status may well predict future falls along with the fear of falling in older community-dwelling adults. Fear of falling that induces sedentary behavior is also likely to exacerbate the risk for incurring frailty states or                    worsening these, as well as falls, regardless of                  sociodemographic factors <xref ref-type="bibr" rid="ridm1841706884">35</xref>. Martin et al. <xref ref-type="bibr" rid="ridm1841880644">11</xref> too        conclude there are close associations between frailty,              sarcopenia, osteoporosis and falls that warrant attention especially in cases where older adults have fallen or               sustained a fracture or both, as these individuals may not only be frail and require a care plan involving both                nutrition and exercises, but also require specific help to prevent future falls. Indeed, Higuchi et al. <xref ref-type="bibr" rid="ridm1841915484">4</xref> found frail elderly who exhibited falling fears to be worse off                  physically speaking than those with no fear attributes. Other data reveal the fear of falling can not only contribute to psychological conditions such as depression, but can also impact on the health-related life quality of frail                elderly people <xref ref-type="bibr" rid="ridm1841703428">36</xref>. </p>
        <p>In short, therefore, although the literature on the current topic of interest is neither robust, nor conclusive, it appears hard to refute a case for the application of both timely as well as effective intervention strategies to                 prevent or reduce frailty among older vulnerable adults. This may not only help to reduce the chances of a high falls risk, but may also be beneficial for preventing excess              frailty, future falls, as well as future falls fears among frail older adults <xref ref-type="bibr" rid="ridm1841700476">37</xref> and should be studied in various                contexts, and in diverse groups of older adults. Explicit attention to identifying and intervening upon excess falls fear beliefs where they prevail also seems imperative. </p>
        <p>Indeed, a recent study of 175 China based                  community dwelling older adults from five districts <xref ref-type="bibr" rid="ridm1841674604">38</xref> showed those study participants who reported having a fear of falling were 7.2 times more likely to be frail than those reporting no such fear, and among those sixty                  percent of cases deemed frail, eighty one percent affirmed they had a fear of falling. Similarly, Perez-Ross et al. <xref ref-type="bibr" rid="ridm1841669924">39</xref> who examined 564 elderly people with a mean age of 76.05 years; and where 83.9 percent were deemed to be pre frail, among the four factors associated with frailty they included a fear of falling. Further findings of                Alcolea–Ruiz et al. <xref ref-type="bibr" rid="ridm1841666756">40</xref> tend to affirm that fear of falling is significantly elevated in the presence of frailty. </p>
        <p>Hence, although frailty represents a highly                challenging negative state of wellbeing among many older adults and one that clearly exposes the sufferer to a                 multitude of potentially preventable adverse health               outcomes <xref ref-type="bibr" rid="ridm1841661644">41</xref>, it appears safe to say that excess frailty can. possibly be averted in part by multiple approaches that might include taking steps to minimize the onset or perpetuation of excess fears related to future falls among those elderly adults deemed most vulnerable. Conversely, in light of the rapidly ageing global population, and the parallel rise in frailty, as well as falls injuries and resultant possible fears of falling, the current social and economic burden of these two conditions alone will undoubtedly continue to rise exponentially if not addressed in a timely manner. In addition, due to associated increases in                 numbers of older adults living to higher ages, older adults with multi morbidities and those who survived COVID-19, soaring healthcare and social care costs and suffering can be anticipated if sporadic or belated preventive efforts remain the norm. </p>
        <p>To address this issue, it is uplifting to see that while more needs to be done, sufficient research does point to the promise of improved health and social                 outcomes for the vulnerable elderly, through insightful and carefully tailored preventive approaches <xref ref-type="bibr" rid="ridm1841659340">42</xref><xref ref-type="bibr" rid="ridm1841654516">43</xref><xref ref-type="bibr" rid="ridm1841649476">44</xref> that do currently exist. These include, but are not limited to multi-component community-based as well as                       home-based approaches and occupational therapy                  strategies designed to improve muscle and bone mass and function believed to help reduce both frailty as well as falls risk <xref ref-type="bibr" rid="ridm1841669924">39</xref><xref ref-type="bibr" rid="ridm1841649476">44</xref><xref ref-type="bibr" rid="ridm1841626244">45</xref><xref ref-type="bibr" rid="ridm1841624660">46</xref><xref ref-type="bibr" rid="ridm1841618828">47</xref>. As well as structured exercises, strength training, or physical activities that involve functional training and coordination exercises <xref ref-type="bibr" rid="ridm1841612492">48</xref>, structured                nutrition interventions <xref ref-type="bibr" rid="ridm1841610764">49</xref>, and/or cognitive behavioral intervention approaches to reduce frailty, as well as falls and the fear of falling may similarly help to increase               independence, confidence and energy <xref ref-type="bibr" rid="ridm1841888004">7</xref><xref ref-type="bibr" rid="ridm1841700476">37</xref><xref ref-type="bibr" rid="ridm1841602916">50</xref>. Further efforts directed towards reducing harmful medications, improving calcium and vitamin D status, diabetes control, and desirable home adaptations <xref ref-type="bibr" rid="ridm1841649476">44</xref><xref ref-type="bibr" rid="ridm1841597660">51</xref><xref ref-type="bibr" rid="ridm1841596868">52</xref>, efforts to provide a person-centered and goal setting approach <xref ref-type="bibr" rid="ridm1841612492">48</xref> and encouraging social engagement <xref ref-type="bibr" rid="ridm1841577884">53</xref> will also likely prove helpful, as will proactive careful screening to                  identify at risk adults <xref ref-type="bibr" rid="ridm1841674604">38</xref><xref ref-type="bibr" rid="ridm1841577884">53</xref><xref ref-type="bibr" rid="ridm1841576156">54</xref>. Programs that try to encourage personal development and growth, in spite of aging, and physical, social, emotional, and economic                environments that foster wellbeing and active aging           appear highly promising as well <xref ref-type="bibr" rid="ridm1841571260">55</xref>.</p>
      </sec>
    </sec>
    <sec id="idm1842011620" sec-type="discussion">
      <title>Discussion</title>
      <p>While aging is inevitable, increasing evidence   suggests aging as a negative state does not have to be a foregone ordained experience of downward spiraling events and perceptions. This review explored the possible contribution of fears of falling to frailty development and exacerbation, along with any observed frailty, falls risk associations with a view to providing more insight into opportunities to limit or avert some age associated              adverse outcomes. These include, but are not limited to a heightened risk of disability, low levels of functional            autonomy, high numbers and impact of one or more comorbid diseases, falls and falls injuries, plus multiple degrees of cognitive impairment.</p>
      <p> On the other hand, while not definitive, and              needing more careful study, it appears safe to say a fairly solid case can be made for the promise of dedicated efforts that attempt to prevent the risk of poor health status and outcomes attributable to frailty in elderly populations, including those elderly who exhibit persistent fears of       falling and/or have fallen as a result of frailty.  As well as preventing frailty where possible, preventing falls is strongly indicated as well, because even those older adults who are healthy, but incur a falls injury or an actual hip fracture injury, may be at risk for frailty that can                  perpetuate a downward spiral of health events, even though their association is clearly complex and largely likely to prove non linear and cumulative [see <xref ref-type="fig" rid="idm1842962964">Figure 1</xref>].</p>
      <fig id="idm1842962964">
        <label>Figure 1.</label>
        <caption>
          <title> Conceptual Model of Multiple Interrelated Factors Potentially Impacting Frailty Cumulatively</title>
        </caption>
        <graphic xlink:href="images/image1.jpg" mime-subtype="jpg"/>
      </fig>
      <p>It is also evident that this is not only an urgent public and social health concern as a whole, but a                 promising new field of endeavor where most peer                   reviewed articles have been published within the last five years and among these several are successful studies that show frailty can be somewhat reversed <xref ref-type="bibr" rid="ridm1841561540">57</xref>. Moreover, those who are less frail are more likely to be more            autonomous and less subject to falls injuries and                    sedentarity <xref ref-type="bibr" rid="ridm1841571260">55</xref>. </p>
      <p>At the same time, and bearing in mind, insights, answers and optimal solutions take considerable time to emerge, attention directed towards those most vulnerable to frailty or becoming frail who appear to be women in the higher age groups, those living in poverty, those with low educational levels, living in unsafe housing who are                    underweight as well as those with diabetes, dementia,      disability, and/or depression and that accepts disability is a part of aging <xref ref-type="bibr" rid="ridm1841557364">58</xref><xref ref-type="bibr" rid="ridm1841555708">59</xref>, as well as those that have a falls history <xref ref-type="bibr" rid="ridm1841877404">8</xref>, might be targeted preferentially using the most promising approaches examined in randomized studies.  These include, but are not limited to various forms of physical activity; physical activity combined with                   nutrition; physical activity plus nutrition plus memory training; home modifications; pre-habilitation (physical therapy plus exercise plus home modifications) and                   comprehensive geriatric assessments <xref ref-type="bibr" rid="ridm1841548364">60</xref>.</p>
      <p>Alternately, in light of the independent as well as collective impact of both frailty and falls fears on multiple personal dimensions of health, as well as the broader              social and political dimensions of ‘wellbeing’ <xref ref-type="bibr" rid="ridm1841571260">55</xref>, the       failure to address this burgeoning issue in an integrated rather than a fragmented manner will predictably produce higher levels of irreversible disability, hospitalization, low life quality, and premature deaths than not <xref ref-type="bibr" rid="ridm1841703428">36</xref><xref ref-type="bibr" rid="ridm1841674604">38</xref>.                Moreover, since falls in their own right are not only                increasing in numbers in the elderly, frailty which appears associated with falling and fear of falling to a high                 degree <xref ref-type="bibr" rid="ridm1841566148">56</xref> can undoubtedly be expected to increase if associated fears of falling are neglected and inadvertently reduce activity involvement as well as involvement in   rehabilitation interventions <xref ref-type="bibr" rid="ridm1841596868">52</xref><xref ref-type="bibr" rid="ridm1841544260">61</xref>.</p>
      <p>To this end, ample evidence implies an urgent need for multiple far reaching collective efforts to better understand why some older adults are more vulnerable to frailty than others, and to more effectively discriminate and untangle the most promising potentially preventable antecedents using actionable preventative approaches. There must also surely be improved practical efforts to not only avert falls as well as falls fears, but to better                     understand the origins of falls attributable to excess fear that can prevail even in the absence of any actual overt falls experience. Based on the current literature, it also appears comprehensive assessments, longitudinal                      exploratory studies, plus an inter disciplinary approach, along with well designed efficacy studies that focus on heightening positive cognitions, provider knowledge, falls self-efficacy, efforts to counter the multiple negative                 mythologies of aging as purely a declining and negative economic state, plus personalized home-based one         dimensional or multi component exercise interventions, and the provision of access to safe indoor and outdoor environments, efficacious social support, medication             safety, and needed nutrient and educational resources will be especially helpful in this regard and are strongly                 encouraged <xref ref-type="bibr" rid="ridm1841538284">62</xref><xref ref-type="bibr" rid="ridm1841534180">63</xref><xref ref-type="bibr" rid="ridm1841530220">64</xref><xref ref-type="bibr" rid="ridm1841525252">65</xref><xref ref-type="bibr" rid="ridm1841523092">66</xref><xref ref-type="bibr" rid="ridm1841585804">67</xref><xref ref-type="bibr" rid="ridm1841469236">68</xref>.</p>
    </sec>
    <sec id="idm1841959036" sec-type="conclusions">
      <title>Conclusions </title>
      <p>
        <italic>Based on the Prevailing  Data, it is Concluded that</italic>
      </p>
      <p>I. Fear of falling is a potentially reversible correlate of frailty among the elderly.</p>
      <p>II. Further research, plus personalized home-based                community wide preventive efforts and treatments to address both frailty, as well as falls fears hold the             potential to improve the lives of many older frail, as well as pre frail older adults as well as healthy adults.</p>
      <p>III. Anticipated are enhancements in longevity, functional capacity, and life quality.</p>
      <p>IV. Additional anticipated benefits are reductions in health care social and economic costs.</p>
    </sec>
  </body>
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