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 <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd"> <article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.0" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JNDC</journal-id>
      <journal-title-group>
        <journal-title>Journal of New Developments in Chemistry</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2377-2549</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">JNDC-21-3977</article-id>
      <article-id pub-id-type="doi">10.14302/issn.2377-2549.jndc-21-3977</article-id>
      <article-categories>
        <subj-group>
          <subject>research-article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>A Cross Section Survey Assessment Study on the Knowledge and Practice of Periodic Medical Check up among the Saudi population </article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Muazzam</surname>
            <given-names>Sheriff Maqbul</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843013180">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Rawabi</surname>
            <given-names>Dafallah Alghamdi</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843010156">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Lama</surname>
            <given-names>Waleed Bakhsh</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843010156">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Nadya</surname>
            <given-names>Awad Almashjari</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843010156">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Shamukh</surname>
            <given-names>Hamid Alanazi</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843010156">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Amjad</surname>
            <given-names>Abdulqader bahshwan</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843010156">2</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Aejaz</surname>
            <given-names>Abdullatif Khan</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843132444">3</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>S.M.</surname>
            <given-names>Shakeel Iqubal</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843132444">3</xref>
          <xref ref-type="aff" rid="idm1843129924">*</xref>
        </contrib>
        <contrib contrib-type="author">
          <name>
            <surname>Abdul</surname>
            <given-names>Rahman Ikbal</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843132444">3</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1843013180">
        <label>1</label>
        <addr-line>Department of Microbiology and Immunology, Ibn Sina National College for Medical Studies, Al  Mahjar Street: 31906, Jeddah 21418, Kingdom of Saudi Arabia</addr-line>
      </aff>
      <aff id="idm1843010156">
        <label>2</label>
        <addr-line>Medicine Program, Ibn Sina National College for Medical Studies, Al Mahjar Street: 31906, Jeddah 21418, Kingdom of Saudi Arabia.</addr-line>
      </aff>
      <aff id="idm1843132444">
        <label>3</label>
        <addr-line>Department of General Science, Ibn Sina National College for Medical Studies, Al Mahajar Street: 31906, Jeddah 21418, Kingdom of Saudi Arabia</addr-line>
      </aff>
      <aff id="idm1843129924">
        <label>*</label>
        <addr-line>Corresponding author</addr-line>
      </aff>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Weihe</surname>
            <given-names>Zhang</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842866148">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842866148">
        <label>1</label>
        <addr-line>2100 Riverchase Center Bldg 200, Suite 200 Birmingham, Al 35244 U.S.A.</addr-line>
      </aff>
      <author-notes>
        <corresp>
    
    S.M. Shakeel Iqubal, <addr-line>Department of General Science, Ibn Sina National College for Medical Studies, Al Mahajar Street: 31906, Jeddah 21418, Kingdom of Saudi Arabia.</addr-line><email>shakeeliqubal@gmail.com</email></corresp>
        <fn fn-type="conflict" id="idm1842798700">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2021-10-23">
        <day>23</day>
        <month>10</month>
        <year>2021</year>
      </pub-date>
      <volume>3</volume>
      <issue>3</issue>
      <fpage>40</fpage>
      <lpage>49</lpage>
      <history>
        <date date-type="received">
          <day>27</day>
          <month>09</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>22</day>
          <month>10</month>
          <year>2021</year>
        </date>
        <date date-type="online">
          <day>23</day>
          <month>10</month>
          <year>2021</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2021</copyright-year>
        <copyright-holder>Muazzam Sheriff Maqbul, et al.</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org/jndc/article/1716">This article is available from http://openaccesspub.org/jndc/article/1716</self-uri>
      <abstract>
        <p>In Saudi Arabia most of the individuals give very little attention to issues like health or no priority to medical checkup. This investigation was carried out to measure knowledge, practice of              periodic medical checkup in Kingdom of Saudi                Arabia people. A cross-sectional investigation was conducted among 1015 participants. A structured interviewer administered an online questionnaire were distribute by social media and whatsApp. We collected data and analyzed using SPSS version 21. Association between categorical variables were            explored using bar chart and tables, Level of               significance was set at 5%. The main age of the       respondents was 21-30 years, 78.4% were females and 64.2% were married. About 42.1% have ever heard of periodic medical check-up , 57% of those who haven’t ever heard of periodic medical checkup and only 21.9% among those who had ever done it had frequent medical check-up and 78.1% didn’t do it. Attempt is required in ensuring that periodic    medical check-up is urged. There is a need to study the factors associated with the uptake of medical check-up among the study population and effort should be made by health agencies to educate traders on the various types of medical check-up, their                indications and benefits as well as its practice                  encouraged</p>
      </abstract>
      <kwd-group>
        <kwd>Awareness</kwd>
        <kwd>Knowledge</kwd>
        <kwd>Periodic Medical check-up</kwd>
        <kwd>Saudi Arabia</kwd>
      </kwd-group>
      <counts>
        <fig-count count="3"/>
        <table-count count="3"/>
        <page-count count="19"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1842864924" sec-type="intro">
      <title>Introduction  </title>
      <p>Periodic Medical Check-up or Routine Medical Checkup (RMC) is a regular primary care process provided by health care facilities for all people of different ages through history taking and physical examination and         laboratory investigation for non- complaining individuals. RMC is helpful and effective to discover new cases and prevent major complications to early intervention but also might be dangerous because all types of medical screening can cause harm. A well‐ known example is false‐positive test can lead to more invasive diagnostic test. Also           false‐negative results may lead to a false sense of              wellbeing and delay medical intervention when needed. And over-diagnosis can cause latent cancers or carcinoma in situ. (RMC) any variation in the health of individuals is observed and handled in the form of curative or                preventive duties or follow–up. Many non-communicable diseases (NCD) as hypertension, breast cancer, cervical cancer, diabetes mellitus and prostate cancer. Currently ailments like obesity, atherosclerosis, myocardial                infarctions and stroke, oncological disease can be detected <xref ref-type="bibr" rid="ridm1849328060">1</xref>. It’s necessary to conduct a periodic medical              examination to reduce chronic diseases, because every year, 9 million people less than 60 years old die in the worldwide because of NCD <xref ref-type="bibr" rid="ridm1849328060">1</xref>. In Kingdom of Saudi              Arabia (KSA) the population suffers from high incidence of preventable chronic illness and most of them is top risk factor that’s leads to death or disability <xref ref-type="bibr" rid="ridm1849393436">2</xref><xref ref-type="bibr" rid="ridm1849338580">3</xref><xref ref-type="bibr" rid="ridm1849173604">4</xref><xref ref-type="bibr" rid="ridm1849175620">5</xref> which have a burden that affects socially and economically and                  represents more than 60% of the global burden of disease. A comprehensive medical examination on a regular basis helps to prevent future illness <xref ref-type="bibr" rid="ridm1849393436">2</xref></p>
    </sec>
    <sec id="idm1842864420">
      <title>General Aims</title>
      <p>1-This study was aimed to assess the awareness of         periodic medical check-up and practice among Saudi       Arabia.</p>
      <p> 2- To evaluate the relation between the periodic medical check-up and reduce the incidence of health complication</p>
    </sec>
    <sec id="idm1842863340">
      <title>Specific Aims</title>
      <p>1- Know and analyze the main factors that leads to        decrease commitment to periodic medical check-up <xref ref-type="bibr" rid="ridm1849338580">3</xref><xref ref-type="bibr" rid="ridm1849173604">4</xref></p>
    </sec>
    <sec id="idm1842863484" sec-type="materials">
      <title>Materials and Methods</title>
      <p>A cross-sectional study was conducted in the       Saudi community used to assess the awareness of periodic medical checks-up among Saudi and Non-Saudi people. The total number of participants was 1015 of both gender and the age was arranged into different stages. Data          collection sources were given an online survey in the            Arabic language  and we were distribute the online          questioner by social media platform and email. On the first page of survey link, it included brief information about our Research and confirmed to participant all the information keeps it confidential and anonymity were ensured all            participants participated voluntarily. After completed the survey we translated to English language to the             questionnaire was multiple choice and included two         sections. First section contained socio demographic data (Gender, age, marital status, educational level,                 occupations).</p>
      <p>And second section was evaluate the knowledge of participants about RMC, ( have you ever had routine checkup , do you regularly checkup , frequency of medical checkup, types of checkup known , causes of poor              implementation of periodic medical checkup , any                improvement during medical checkup ,any complications because lack of periodic medical checkup, is it helpful to discover early problem). And the research investigation was approved by IBN SINA NATIONAL COLLEGE.                 Institutional Human Ethics Committee (H-02-03062021), protocol identification number is 002SRC31052021. The study was carried out for 3 months 'in duration. Microsoft Excel and IBM SPSS20.00 was employed to analyze the collected data for the evaluation</p>
    </sec>
    <sec id="idm1842862548" sec-type="results">
      <title>Result and Discussion</title>
      <p>A total participant 1015 but we were received only 983 answers due to missing or skip response (n=32),we were replaced by the mean values in software SPSS.</p>
      <p>Based on survey result the socio demographic characteristics of the participants were shown in <xref ref-type="table" rid="idm1841819748">Table 1</xref>. In age standard deviation was (1,618) and most of the   participants were in age group 21-30 years (29.9%), then 41-50 years (23.3%), then 51-60 years (19.3%). Then group 31-40 years then group of age less than 20 years (10.3%) and least≥60years (6.1%). In gender standard deviation was (4.527%) and the number of females 796 (78.4%) were significantly higher than male 219 (21.6%). the marital status were mostly is married people (64.2%) then single people (27.3%), divorced (4.5%), widower (3.9 %). The education levels were most of participants were University education (65.9%), followed by              secondary (23.3%), postgraduate (5.8%), intermediate (3.4%), elementary (1.1%) and lastly illiterate (0.4%). In the occupation part (31.4%) were unemployed, (22.4%) in educational sector , (15.75%)  retired  (11.9%) in  private sector, (8.9%) Medical sector, others (6.3%), government sector (3.4%). When we asked about the chronic disease most of participants answered they did not have chronic disease. </p>
      <table-wrap id="idm1841819748">
        <label>Table 1.</label>
        <caption>
          <title> Socio demographic characteristics of the participant</title>
        </caption>
        <table rules="all" frame="box">
          <tbody>
            <tr>
              <th>
                <bold>Characteristic</bold>
              </th>
              <td>
                <bold>Value/ Total</bold>
              </td>
              <td>
                <bold>%</bold>
              </td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Age </bold>
              </th>
            </tr>
            <tr>
              <td>21-30 yr</td>
              <td>253</td>
              <td>24.9</td>
            </tr>
            <tr>
              <td>Less than 20 yr</td>
              <td>105</td>
              <td>10.3</td>
            </tr>
            <tr>
              <td>31-40 yr</td>
              <td>163</td>
              <td>16.1</td>
            </tr>
            <tr>
              <td>41-50 yr</td>
              <td>236</td>
              <td>23.3</td>
            </tr>
            <tr>
              <td>51-60 yr</td>
              <td>196</td>
              <td>19.3</td>
            </tr>
            <tr>
              <td>More than 60 yr</td>
              <td>62</td>
              <td>6.1</td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Gender </bold>
              </th>
            </tr>
            <tr>
              <td>Female</td>
              <td>796</td>
              <td>78.4</td>
            </tr>
            <tr>
              <td>Male</td>
              <td>219</td>
              <td>21.6</td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Marital status </bold>
              </th>
            </tr>
            <tr>
              <td>Single</td>
              <td>277</td>
              <td>27.3</td>
            </tr>
            <tr>
              <td>Married</td>
              <td>652</td>
              <td>64.2</td>
            </tr>
            <tr>
              <td>Widower</td>
              <td>40</td>
              <td>3.9</td>
            </tr>
            <tr>
              <td>Divorced</td>
              <td>46</td>
              <td>4.5</td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Educational level </bold>
              </th>
            </tr>
            <tr>
              <td>Illiterate</td>
              <td>4</td>
              <td>0.4</td>
            </tr>
            <tr>
              <td>Elementary</td>
              <td>11</td>
              <td>1.1</td>
            </tr>
            <tr>
              <td>Intermediate</td>
              <td>35</td>
              <td>3.4</td>
            </tr>
            <tr>
              <td>Secondary</td>
              <td>237</td>
              <td>23.3</td>
            </tr>
            <tr>
              <td>University</td>
              <td>669</td>
              <td>65.9</td>
            </tr>
            <tr>
              <td>Postgraduate</td>
              <td>59</td>
              <td>5.8</td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Occupations </bold>
              </th>
            </tr>
            <tr>
              <td>Unemployed</td>
              <td>319</td>
              <td>31.4</td>
            </tr>
            <tr>
              <td>Retired</td>
              <td>159</td>
              <td>15.75</td>
            </tr>
            <tr>
              <td>Private</td>
              <td>121</td>
              <td>11.9</td>
            </tr>
            <tr>
              <td>Educational sector</td>
              <td>227</td>
              <td>22.4</td>
            </tr>
            <tr>
              <td>Medical sector</td>
              <td>90</td>
              <td>8.9</td>
            </tr>
            <tr>
              <td>Government sector</td>
              <td>35</td>
              <td>3.4</td>
            </tr>
            <tr>
              <td>
                <bold>Others</bold>
              </td>
              <td>64</td>
              <td>6.3</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <p> In <xref ref-type="table" rid="idm1841743204">Table 2</xref>, About the frequency of periodic              medical check-up most of participants did checkups every six months (46.9%) , the second largest participants did check-ups yearly (35.0%), only 81 (8.0%) had check-ups every two years, and the 103 (10.1%) of population didn’t know when checkups. Then we asked about types of          periodic medical check-up known the most of the             participants know general examination 479 (47.7%), only 10 (1.0%) know visual checkup, the known check blood sugar were (4.2%) and know blood pressure check (1.7%), and know dental check (2.6%) the second largest participants know all the above checkups (43.4%). Causes of poor implantation of periodic medical check-up,  most of the participants didn’t get regular checkup because low socio-economic class 409 (40.3%) , the second largest         participants cause far away (33%), only other cases (4.5%), the cause of lack primary health care (22.2%).</p>
      <table-wrap id="idm1841743204">
        <label>Table 2.</label>
        <caption>
          <title> Frequency of periodic medical check-up</title>
        </caption>
        <table rules="all" frame="box">
          <tbody>
            <tr>
              <th>
                <bold>Characteristic</bold>
              </th>
              <td>
                <bold>Value/ Total</bold>
              </td>
              <td>
                <bold>%</bold>
              </td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Frequency of Medical check up </bold>
              </th>
            </tr>
            <tr>
              <td>Every 6 months</td>
              <td>476</td>
              <td>46.9</td>
            </tr>
            <tr>
              <td>Yearly</td>
              <td>355</td>
              <td>35</td>
            </tr>
            <tr>
              <td>Every 2 years</td>
              <td>81</td>
              <td>8</td>
            </tr>
            <tr>
              <td>I don't know</td>
              <td>103</td>
              <td>10.1</td>
            </tr>
            <tr>
              <td>Total</td>
              <td>1015</td>
              <td>100</td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Types of Periodic Medical check up </bold>
              </th>
            </tr>
            <tr>
              <td>General examination</td>
              <td>479</td>
              <td>47.2</td>
            </tr>
            <tr>
              <td>Blood pressure</td>
              <td>17</td>
              <td>1.7</td>
            </tr>
            <tr>
              <td>Blood sugar</td>
              <td>43</td>
              <td>4.2</td>
            </tr>
            <tr>
              <td>Visual</td>
              <td>10</td>
              <td>1</td>
            </tr>
            <tr>
              <td>Dental</td>
              <td>25</td>
              <td>2.5</td>
            </tr>
            <tr>
              <td>All above</td>
              <td>441</td>
              <td>43.4</td>
            </tr>
            <tr>
              <th colspan="3">
                <bold>Causes of poor Implantation Periodic Medical check up </bold>
              </th>
            </tr>
            <tr>
              <td>Lack primary health care</td>
              <td>225</td>
              <td>22.2</td>
            </tr>
            <tr>
              <td>Low socio-economic class</td>
              <td>409</td>
              <td>40.3</td>
            </tr>
            <tr>
              <td>Far away</td>
              <td>335</td>
              <td>33</td>
            </tr>
            <tr>
              <td>Other causes</td>
              <td>46</td>
              <td>4.5</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <p>In <xref ref-type="table" rid="idm1841675172">Table 3</xref>, when we asked the participants about have you ever had a routine medical check-up (42.1% ) choose yes (57.8%) choose No. Also When we asked the participants when periodic medical check-up is done we were find there was not a big difference between              participants who choose they do routine check-up when they feel well (43.9%) and who choose doing it during illness (40.8%) some of participants choose other causes (15.2%). about the regularity of periodic medical check-up most of the participants don’t regularly do medical              check-up (78.1%) while (21.9%) do. Who choose they do routine check-up when they feel well (43.9%) and who choose doing it during illness ( 40.8%) some of                    participants choose other causes (15.2%) . about the          regularity of periodic medical check-up Most of the             participants don’t regularly do medical check-up (78.1%) while (21.9%) do.</p>
      <table-wrap id="idm1841675172">
        <label>Table 3.</label>
        <caption>
          <title> Frequency of periodic medical check-up</title>
        </caption>
        <table rules="all" frame="box">
          <tbody>
            <tr>
              <td>Questions</td>
              <td>Value / %</td>
            </tr>
            <tr>
              <td>Have you ever had a routine Medical check-up ? (n=1015)</td>
              <td> </td>
            </tr>
            <tr>
              <td>Yes</td>
              <td>428 (42.1)</td>
            </tr>
            <tr>
              <td>No</td>
              <td>587 (57.8)</td>
            </tr>
            <tr>
              <td>When Periodic Medical check-up is done?</td>
              <td> </td>
            </tr>
            <tr>
              <td>When one is healthy</td>
              <td>447  (43.9)</td>
            </tr>
            <tr>
              <td>During illness</td>
              <td>414  (40.8)</td>
            </tr>
            <tr>
              <td>Others</td>
              <td>154  (15.2)</td>
            </tr>
            <tr>
              <td>Do you regularly check-up ?</td>
              <td> </td>
            </tr>
            <tr>
              <td>Yes</td>
              <td>223 ( 21.9)</td>
            </tr>
            <tr>
              <td>No</td>
              <td>792 (78.1)</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <p>Most of participants choose (I am not  a regular in my periodic medical check-up 71.6%)</p>
      <p>The second largest participants choose yes. They notice improvement in their health level during regular check-up (22.0%), only  (6.4%) choose No.</p>
      <p>58% choose no they didn't notice any                complications because of lack of commitment in periodic medical check-up and 41.7% choose yes.</p>
      <p>Most of participants choose yes the periodic           medical check-up help them to discover health problems early and treat them (61.0%). 39.0% and other group of people choose no.</p>
      <p>We asked about the improvement during regular periodic medical check-up Most of participants choose (I am not a regular in my periodic medical check-up 71.6%) the second largest participants choose yes. They notice improvement in their health level during regular check-up (22.0%), only (6.4%) choose No. about the complication due to lack of periodic medical check-up 58% choose no, they didn't notice any complications because of lack of commitment in periodic medical check-up. And 41.7% choose yes. For, is it help to discover newly health             problem, most of participants choose yes the periodic medical check-up help them to discover health problems early and treat them (61.0%) and 39.0% other group of people choose no. <xref ref-type="fig" rid="idm1841660196">Figure 1</xref>, <xref ref-type="fig" rid="idm1841658684">Figure 2</xref>, <xref ref-type="fig" rid="idm1841657892">Figure 3</xref></p>
      <fig id="idm1841660196">
        <label>Figure 1.</label>
        <caption>
          <title> Frequency of Medical check-up or not?</title>
        </caption>
        <graphic xlink:href="images/image1.jpg" mime-subtype="jpg"/>
      </fig>
      <fig id="idm1841658684">
        <label>Figure 2.</label>
        <caption>
          <title> Types of medical check-up known</title>
        </caption>
        <graphic xlink:href="images/image2.jpg" mime-subtype="jpg"/>
      </fig>
      <fig id="idm1841657892">
        <label>Figure 3.</label>
        <caption>
          <title> What do you think causes of poor implantation periodic medical check-up</title>
        </caption>
        <graphic xlink:href="images/image3.jpg" mime-subtype="jpg"/>
      </fig>
      <p>In KSA they found high rate of un-diagnostic and diagnostic chronic disease this study was planned to             investigate the causes of low uptake of RMC and try to modify the causes among Saudi population (LOW –UPTAKE). <xref ref-type="bibr" rid="ridm1849175620">5</xref><xref ref-type="bibr" rid="ridm1849167284">6</xref><xref ref-type="bibr" rid="ridm1849162604">7</xref><xref ref-type="bibr" rid="ridm1849152644">8</xref><xref ref-type="bibr" rid="ridm1849157324">9</xref><xref ref-type="bibr" rid="ridm1849155812">10</xref><xref ref-type="bibr" rid="ridm1849140172">11</xref><xref ref-type="bibr" rid="ridm1849134268">12</xref></p>
      <sec id="idm1842745652">
        <title>Exposure to (RMC) and Age</title>
        <p>Chi-square test was used to determine the                 relationship between age and exposure to a periodic           medical checkup. Significant p-values was &lt;0.001, there was no significant difference.  The most frequent age group exposed to periodic medical checkups 41-50 years and 51-60 years then 21-30 years, 31-40 years, more than 60 years, less than 20 years and most frequent group not exposed to periodic medical checkup 21-30 years then          41-50 years, 51-60 years, 30-41 years, less than 20 years, more than 60 years. </p>
      </sec>
      <sec id="idm1842745796">
        <title>Exposure (RMC) and Gender </title>
        <p> Chi-square test used to determine the                  relationship between gender and exposure to periodic medical checkup. Significant p-values was 0.025 and &lt;0.001 there was significant difference. Frequent               distribution revealed most female exposed to periodic medical checkup than males.</p>
      </sec>
      <sec id="idm1842745436">
        <title>Time of did (RMC) and Marital Status:</title>
        <p>Chi-square test used to determine the                        relationship between marital status and time of did                periodic medical checkup. Significant p-values was zero frequency distribution revealed most of married were   visited hospital when one is healthy and the second             largest group attempted to hospital when one is healthy single people, divorced, widower. Other married people (low rate) attempted to hospital only during illness, single people (larger than who attempt when one is healthy), divorced and widower.</p>
      </sec>
      <sec id="idm1842744356">
        <title>Time of did (RMC) and Education</title>
        <p>Chi-square test was used to determine the             relationship between educations and time of did periodic medical checkup. Significant p-value was 0.668 &lt;0.001 there was no significant difference. According to             frequency distribution most of participant who university education visit hospital when one is healthy and others university educated choose only during illness, and few of them choose in other cases and about secondary                 education only visit hospital in case of illness. Others choose when one is healthy. Few of them choose in others cases. About postgraduate participants most of them when one is healthy and others postgraduate choose only during illness and few of them choose in other cases.</p>
      </sec>
      <sec id="idm1842745292">
        <title>Regularity on (RMC) and Occupations</title>
        <p>Chi-square test was used to determine the               relationship between occupations and regularity on (RMC)significant p-value was 0.002 &lt;0.001 there was significant difference, frequency distribution revealed most of           participants answered not regular on (RMC) they were unemployed then educational sector, retired, private          sector, medical sector. Others occupations and lastly            government sector.</p>
        <p>The few of participant who visit the hospital to (RMC) on regular were from unemployed then educational sector, retired, private sector, medical sector, sector          government sector and last group from other occupations.</p>
        <p>Results of chi-square test between routine           medical check-up and types of medical check-up known showed that there is no statistically significant; since chi square had p-value 0.655&gt;0.05 And results of chi-square test between routine medical check-up and frequency of medical checkup or not showed that there is no                statistically significant; since chi square had p-value 0.837&gt;0.05 results of chi-square test between routine medical check-up and causes of poor implantation of             periodic medical checkup showed that there is no            statistically significant; since chi square had                             p-value0.625&gt;0.05.</p>
        <p>Results of chi-square test between regularly                medical check-up or not and frequency of medical checkup or not showed that there is no statistically significant; since chi square had p-value 0.093&gt;0.05.</p>
        <p> Results of chi-square test between regularly               medical check-up or not and types of medical checkup known showed that there is statistically significant; since chi square had p-value 0.04&lt;0.05.participants with regular checkup and types of medical checkup known the first large group revealed mostly general examinations the   second group blood sugar check.</p>
        <p>Results of chi-square test between regularly             medical check-up or not and causes of poor implantation of periodic medical checkup showed that there is no          statistically significant; since chi square had p-value 0.193&gt;0.05.</p>
        <p> Results of chi-square test between routine               medical check-up and periodic medical check-up is done showed that there is statistically significant; since chi square had p-value 0.00&lt;0.05</p>
        <p>Frequency participants with ever had a routine medical checkup when periodic medical checkup is done revealed most when one is healthy and second largest group during illness.</p>
        <p> Results of chi-square test between routine              medical check-up and regular checkup showed that there is statistically significant; since chi square had p-value 0.00&lt;0.05. Frequency participants with ever had a routine medical checkup high score level no regular medical check-up then participants with a low score level do regular check-up.</p>
        <p>Results of chi-square test between periodic             medical check-up and regular checkup showed that there is statistically significant; since chi square had p-value 0.00&lt;0.05. Participants with periodic medical checkup and regular medical check-up is done revealed most regular is health and second largest group irregular during illness.</p>
        <p>Results of chi-square test between frequency of medical check-up and causes of poor implantation of              periodic check-up showed that there is statistically             significant; since chi square had p-value 0.00&lt;0.05.            Participants with frequency of medical poor implantation of  periodic check-up revealed most low socioeconomic class the second cause away.</p>
        <p>Results of chi-square test between frequency of medical check-up and types of medical check-up showed that there is statistically significant; since chi square had  p-value 0.00&lt;0.05.</p>
        <p>Participants with frequency of medical checkup mostly every six months second largest group participants with yearly and types of medical checkup know revealed most general examination then blood sugar check.</p>
        <p>Results of chi-square test between causes of poor implantation of periodic medical check-up and types of medical checkup showed that there is statistically                significant; since chi square had p-value 0.00&lt;0.05.</p>
        <p>Participants with causes of poor implantation of periodic medical checkup most cause low socio-economic class, second largest group participants with far away to hospital and the low rate cause lack of primary health care types of medical checkup know revealed most general examination than blood sugar check.</p>
        <p>Chi-square test was used to determine the               relationship between complications of lack of periodic medical check-up  and when medical check-up is done significant p-values was  0.001 &lt;0.05 there was no              significant difference   </p>
        <p> Chi-square test used to determine the                       relationship between did you notice any improvment in your health level during the regular check-up? and do         regularly check-up or not? Significant p-values was 0.395  and &lt;0.05 there was  no significant difference. </p>
        <p> Chi-square test used to determine the                   relationship between did periodic examination help you to discover health problems? and do you regularly check-up significant p-value was 0.574. </p>
        <p>Chi-square test was used to determine the                 relationship between did periodic examination help you to discover health problems? and when medical check-up is done significant p-value was 0.721  &gt;0.05 there was significant difference      </p>
        <p>Chi-square test was used to determine the               relationship between complications of lack of periodic medical check-up? and do you regularly check-up               significant p-value was 0.395  &gt;0.05 there was significant difference.</p>
        <p>Chi-square test was used to determine the                   relationship between complications of lack of periodic medical check-up? and have you ever had a routine               medical  check-up significant p-value was 0.0673 &gt;0.05 there was significant difference.</p>
        <p>Chi-square test used to determine the                          relationship between did you notice any improvement in your health level during the regular check-up? and have you ever had a routine medical check-up significant                   p-values was  0.001 and &lt;0.05 there was  no significant difference.</p>
        <p>Chi-square test used to determine the                   relationship between did periodic examination help you to discover health problems? and have you ever had a              routine medical</p>
        <p>Check-up significant p-values was .447 &gt;0.05 there was significant difference</p>
        <p>Chi-square test was used to determine the               relationship between complications of lack of periodic medical check-up? and when the medical check-up is done? Significant p-value was 0.223 &gt;0.05 there was significant difference.</p>
      </sec>
    </sec>
    <sec id="idm1842740324" sec-type="conclusions">
      <title>Conclusion</title>
      <p>In this study, periodic medical check-up is one of the most important tool of preventive medicine used to detect early diseases. An enormous response of more than 1000 was been achieved and a sample of 1015 was            studied using the chi-test to calculate the p-value and an average significance of 0.5% was achieved. The most            active participation was observed from the age group           (21-30 years) and female participants outnumbered the male. The highly prevalence of low uptake of the periodic medical check-up despite high level of awareness (RMC) among Saudi population as its highly associated with low socio-economic class and far away. We recommended  increase number of primary care to use periodic medical check-up and identify the disease and prevent                  complication. This study also shows that it is highly        essential to recommend for conducting campaign in schools and universities and other activities as an annual medical check-ups camps. The early detection of any               disease can serve as a boon in controlling many diseases at its acute early stages rather than leading to the chronic life threatening diseases. This, study thus suggests the need of conducting the routine medical check-ups to            eliminate the adverse life threatening complications due to many diseases. Though, the awareness among the           community regarding the periodic medical check-up is excellent but the need for the practical implementation is lacking and the studies similar to this needs to be           conducted on regular basis to analyze the developments in the future.</p>
    </sec>
    <sec id="idm1842739748">
      <title>Contribution of Authors </title>
      <p>All authors have made substantial contribution to the work and approved it for publication. </p>
    </sec>
    <sec id="idm1842740036">
      <title>Funding </title>
      <p>None</p>
    </sec>
  </body>
  <back>
    <ack>
      <p>We would like to acknowledge Ibn Sina National College, Jeddah, Kingdom of Saudi Arabia, for their          constant support. </p>
    </ack>
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