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 <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd"> <article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.0" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JMID</journal-id>
      <journal-title-group>
        <journal-title>Journal of Medical Informatics and Decision Making</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2641-5526</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.14302/issn.2641-5526.jmid-21-3739</article-id>
      <article-id pub-id-type="publisher-id">JMID-21-3739</article-id>
      <article-categories>
        <subj-group>
          <subject>research-article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>A Comprehensive Research Study Literature Review of EPIC© in Terms of Enabling Healthcare Agility: A Report Card</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Johnson</surname>
            <given-names>Ralph J.</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842021572">1</xref>
          <xref ref-type="aff" rid="idm1842018260">*</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842021572">
        <label>1</label>
        <addr-line>Dept. of Lymphoma / Myeloma, UT-MDACC, Unit 429, 1515 Holcombe Blvd, Houston, TX 77030 USA.</addr-line>
      </aff>
      <aff id="idm1842018260">
        <label>*</label>
        <addr-line>Corresponding author</addr-line>
      </aff>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Sasho</surname>
            <given-names>Stoleski</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842158972">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842158972">
        <label>1</label>
        <addr-line>Institute of Occupational Health of R. Macedonia, WHO CC and Ga2len CC, Macedonia.</addr-line>
      </aff>
      <author-notes>
        <corresp>
    
    Ralph J. Johnson (PhD, PA-C+), <addr-line>Dept. of Lymphoma / Myeloma, UT-MDACC, Unit 429, 1515 Holcombe Blvd, Houston, TX     77030     USA</addr-line>, Email: <email>rjjohnson@mdanderson.org</email></corresp>
        <fn fn-type="conflict" id="idm1842464516">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2021-02-20">
        <day>20</day>
        <month>02</month>
        <year>2021</year>
      </pub-date>
      <volume>1</volume>
      <issue>4</issue>
      <fpage>1</fpage>
      <lpage>21</lpage>
      <history>
        <date date-type="received">
          <day>09</day>
          <month>02</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>13</day>
          <month>02</month>
          <year>2021</year>
        </date>
        <date date-type="online">
          <day>20</day>
          <month>02</month>
          <year>2021</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2021</copyright-year>
        <copyright-holder>Ralph J. Johnson</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org/jmid/article/1583">This article is available from http://openaccesspub.org/jmid/article/1583</self-uri>
      <abstract>
        <sec id="idm1841885684">
          <title>Background</title>
          <p>As healthcare markets have become more dynamic and turbulent, healthcare organizations have evolved by becoming increasingly “Smart-Agile” in their business practices. Smart-Agility definition-ally ensures success due to its inherent ability to rapidly detect and react appropriately to varied and evolving unclear, complex, and seemingly tumultuous situations and produce high-quality, low-cost goods and services with high customer satisfaction. Thus, there is a vital need for Smart-Agile healthcare IT systems for collection, analyses, and reporting of substantial quantities of healthcare data to inform patient treatment and organizational decisions. EPIC® and its meaningful-use components appear increasingly popular, capturing a majority portion of the healthcare Electronic Healthcare Records (EHR) IT market (&gt;~30%).Yet, there are few, if any, studies reporting on EPIC in terms of Smart-Agility. </p>
        </sec>
        <sec id="idm1841887124">
          <title>Aim</title>
          <p>The intent of this article is to report a systematic review of scientific literature regarding EPIC’s healthcare IT systems meaningful-use features cross-compared with Smart-Agility aspects to produce a positive vs. negative report card—and whether its features are critical vs. non-critical in terms of Smart-Agility.</p>
        </sec>
        <sec id="idm1841887052">
          <title>Method</title>
          <p>Findings reported herein derive from a grounded, iterative review of open-source, peer-reviewed scientific literature following PRISMA. </p>
        </sec>
        <sec id="idm1841885324">
          <title>Findings</title>
          <p>Report card results were mixed. EPIC clearly succeeds and excels (better than average) on                Smart-Agile healthcare IT system core aspects that are the most central, critical and valuable in terms of informing healthcare organizations’ decisions and their patients’ care (6 out of 7; B+, -A), specifically: Standardized Data Collection / Connectivity, Real-Time Data Warehousing/Outcome Measures, Enhanced Patient Safety, Patient Tracking and Follow-up (Continuity of Care), Patient Involvement, and Potential Use in Medical Education. The only critical core criterion it failed on was End-User Satisfaction, and some of that appears to dissipate with new users’ software familiarity.</p>
        </sec>
        <sec id="idm1841885396">
          <title>Conclusion</title>
          <p>EPIC provides a solid and relatively inexpensive foundation with great potential for enabling Smart Agility in healthcare organizations with its high-quality collection and management of vast amounts of                   inter-connected raw data, auto-analysis, and fast report generation. But it does so with hidden costs and inefficiencies. Avenues of further inquiry are suggested.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>Agility</kwd>
        <kwd>Electronic Health Records</kwd>
        <kwd>EHR systems</kwd>
        <kwd>EPIC</kwd>
        <kwd>Healthcare Information Technology</kwd>
        <kwd>Meaningful Use</kwd>
      </kwd-group>
      <counts>
        <fig-count count="1"/>
        <table-count count="1"/>
        <page-count count="21"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1841883380">
      <title>Background</title>
      <p>As current healthcare business environments become increasingly dynamic and turbulent <xref ref-type="bibr" rid="ridm1842574324">1</xref><xref ref-type="bibr" rid="ridm1842581172">2</xref><xref ref-type="bibr" rid="ridm1842681100">3</xref>, many organizations have adapted successfully by adopting a concept of “agility” into their processes. <xref ref-type="bibr" rid="ridm1842574324">1</xref><xref ref-type="bibr" rid="ridm1842581172">2</xref><xref ref-type="bibr" rid="ridm1842427660">4</xref><xref ref-type="bibr" rid="ridm1842433852">5</xref><xref ref-type="bibr" rid="ridm1842417148">6</xref><xref ref-type="bibr" rid="ridm1842414412">7</xref><xref ref-type="bibr" rid="ridm1842403636">8</xref>. Although the concept of agility originally derived from the manufacturing sector <xref ref-type="bibr" rid="ridm1842681100">3</xref><xref ref-type="bibr" rid="ridm1842396652">9</xref>, it has been increasingly transferred and incorporated throughout modern enterprises in general, especially the field of              healthcare <xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842371468">11</xref>. Simply defined, agility means rapidly       responding to changing market conditions in order to acquire a position to take advantage and optimize opportunities <xref ref-type="bibr" rid="ridm1842574324">1</xref><xref ref-type="bibr" rid="ridm1842427660">4</xref><xref ref-type="bibr" rid="ridm1842370316">12</xref><xref ref-type="bibr" rid="ridm1842366212">13</xref><xref ref-type="bibr" rid="ridm1842355684">14</xref><xref ref-type="bibr" rid="ridm1842354028">15</xref>. Agility eponymously ensures the probability of successful operations by virtue of its ability to quickly detect and respond to any given situation. <xref ref-type="bibr" rid="ridm1842347332">16</xref><xref ref-type="bibr" rid="ridm1842344236">17</xref><xref ref-type="bibr" rid="ridm1842357700">18</xref><xref ref-type="bibr" rid="ridm1842335628">19</xref><xref ref-type="bibr" rid="ridm1842332532">20</xref><xref ref-type="bibr" rid="ridm1842329940">21</xref> Agility also means continuous quality improvement by encouraging market-performance alignment within organizational strategic objectives. <xref ref-type="bibr" rid="ridm1842574324">1</xref> The challenge arises out of extensive and varied operations in uncertain, complex, ambiguous, dynamic, and turbulent conditions <xref ref-type="bibr" rid="ridm1842574324">1</xref>. Agile organizations are considered able to swiftly discern and conceive high-quality, low-cost, and high customer satisfaction-providing products, services, and solutions delivered within short suspense deadlines. <xref ref-type="bibr" rid="ridm1842574324">1</xref> This highlights the need for information technology and systems for detection of intra-organization and external market characteristics and performance criteria in healthcare organizations. This requires large quantities of data and the infrastructure to collect and analyze it accurately and efficiently. <xref ref-type="bibr" rid="ridm1842574324">1</xref><xref ref-type="bibr" rid="ridm1842433852">5</xref><xref ref-type="bibr" rid="ridm1842326628">22</xref><xref ref-type="bibr" rid="ridm1842323604">23</xref><xref ref-type="bibr" rid="ridm1842311004">24</xref></p>
      <p>There have been specific Information             Technology (IT) tools developed to enable organizations responsiveness to market changes, particularly in the healthcare industries, that have been studied in terms of their efficaciousness <xref ref-type="bibr" rid="ridm1842347332">16</xref><xref ref-type="bibr" rid="ridm1842306036">25</xref><xref ref-type="bibr" rid="ridm1842301428">26</xref>. Also,              for healthcare organizations, there are certified              off-the-shelf, on-the-spot, one-resource electronic records (EHR) software systems that have become popular choices. This is due to federal and state mandates and incentives for the adoption of “meaningful use” software that offer varying potential to inform and promote Smart-Agile patient medical treatment and organizational decisions.<xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842262524">30</xref><xref ref-type="bibr" rid="ridm1842261156">31</xref><xref ref-type="bibr" rid="ridm1842256764">32</xref><xref ref-type="bibr" rid="ridm1842253020">33</xref><xref ref-type="bibr" rid="ridm1842252444">34</xref><xref ref-type="bibr" rid="ridm1842279948">35</xref> For most healthcare organizations caught in the rub, the sensible choice has been EPIC ®<xref ref-type="bibr" rid="ridm1842276636">36</xref>, which has recently (circa 2019) and rapidly garnered well over 30% of the EHR market share and is seeking substantially more  shares in other electronic records markets (e.g., academic, legal, human resources).<xref ref-type="bibr" rid="ridm1842217100">37</xref><xref ref-type="bibr" rid="ridm1842216020">38</xref> Therefore, it is only sensible to conduct a systematic review and evaluation of EPIC’s meaningful use features in accordance with their relevance to smart enabling of healthcare organizations’ agility, including: standardized data collection,                 technological somnambulism, time commitments and productivity, real-time data warehousing and                (patient-centered) efficient production of outcome measures, enhanced patient safety, patient tracking and follow-up, end-user satisfaction, reminders, patient involvement, and potential use in medical education / training <xref ref-type="bibr" rid="ridm1842216020">38</xref>. Yet, despite EPIC’s preeminence in healthcare IT, there are few, if any, such appraisals on its contributions to Smart-Agility. Therefore, the intent of this article is to report a systematic and comprehensive review and assessment of EPIC’s meaningful use features compared against what is termed aspects of Smart-Agile IT healthcare systems <xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842371468">11</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref> the ultimate aim of this work being the provision of a     Smart-Agile report card for EPIC. Note, this is a review of EPIC only and only in terms of its meaningful use features cross-compared with Smart-Agility. EPIC is in no way considered representative of any other or all meaningful use EHR software, though in terms of other software being meaningful use EPIC may be reflective of those software(s). EPIC’s examination here is justified in that it is currently the most popular and ubiquitous EHR software according to market share.</p>
    </sec>
    <sec id="idm1841883668" sec-type="methods">
      <title>Method</title>
      <p>The findings in this article derive from a              5-phased systematic, iterative “theoretic grounded”  <xref ref-type="bibr" rid="ridm1842209396">40</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><xref ref-type="bibr" rid="ridm1842202772">42</xref> literature review on EPIC in terms of the Smart-Agility that is depicted in <xref ref-type="fig" rid="idm1841417412">Figure 1</xref>.</p>
      <fig id="idm1841417412">
        <label>Figure 1.</label>
        <caption>
          <title> “Grounded” Literature Review</title>
        </caption>
        <graphic xlink:href="images/image1.jpg" mime-subtype="jpg"/>
      </fig>
      <p>(<xref ref-type="fig" rid="idm1841417412">Figure 1</xref>) depicts the PRISMA evidence-based and best practices literature review research process that informed the work reported herein. Open-source peer-reviewed articles from multiple sources were identified and reviewed and conceptual themes  generated. This process adhered to general                       best-practices guidelines and stipulations as per  PRISMA <xref ref-type="bibr" rid="ridm1842199100">43</xref><xref ref-type="bibr" rid="ridm1842194636">44</xref><xref ref-type="bibr" rid="ridm1842188948">45</xref> in order to provide a best-practices standard of a high-degree of independence and transparency to the methodological process. Also, following the PRISMA process in terms of a literature review depicted in a PRISMA diagram helps ensure: (1) a depiction of inclusion / exclusion criteria                representativeness and comprehensiveness of the literature review; and, (2) exclusion of irrelevant literature (i.e., filler). <xref ref-type="bibr" rid="ridm1842199100">43</xref><xref ref-type="bibr" rid="ridm1842194636">44</xref><xref ref-type="bibr" rid="ridm1842188948">45</xref></p>
      <p>Essentially, <xref ref-type="fig" rid="idm1841417412">Figure 1</xref> depicts the steps in this process. Step one involved deriving relevant keywords with which to search for articles and the results from a general canvassing of appropriate peer-reviewed medical/health and open-source subject matter    databases, and applying search terms to the databases. Step two was reviewing abstracts or executive              summaries for relevance, and retrieving relevant articles. Step three was identification and enumeration of themes and the retrieval of related information for review until all themes were exhausted. Step four was the actual review with a fifth step, which was cross-comparisons against Smart-Agile healthcare IT systems aspects also derived from the literature and reported throughout the Findings. Given that the process is “theoretically grounded” <xref ref-type="bibr" rid="ridm1842209396">40</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref>, though the steps are generally sequential and linear, they can be repeated individually or the researcher can cycle back and forth between steps. However, the eventual and ultimate aim was relatively comprehensive literature review that resulted in the identification, summation, and exhaustion of all themes. The one limitation in this method is that not all possible themes in the universe may have been identified. <xref ref-type="bibr" rid="ridm1842209396">40</xref> However, this does not suggest that those identified herein are any more or less important or meaningful. </p>
      <p>Themes are basic summary statements along with controverted issues (if any) that synthesize whether a meaningful use criteria meets Smart-Agility in terms of nominal presence and absence and backed-up with referenced citations. Note, there is no universal and absolute list of Smart-Agile aspects and these were culled from the Smart-Agility literature too (150). (Nevertheless, Dimirken’s <xref ref-type="bibr" rid="ridm1842401836">10</xref> seminal work is about the most comprehensive yet concise inventory.) Also, there was an avoidance of reporting deep delving into controverted issues in the interest of space limitations and avoiding confusion.</p>
    </sec>
    <sec id="idm1841881796">
      <title>Findings</title>
      <sec id="idm1841882012">
        <title>Standardized Information/Data Collection (Connectivity)</title>
        <p>The hallmark of Smart-Agile healthcare IT systems and a critical aspect is their ability to “demonstrate unprecedented potential for fast delivery of automated intelligent and sustainable healthcare services,” <xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref><xref ref-type="bibr" rid="ridm1842209396">40</xref> which EPIC clearly attains. Smart-Agile health care IT systems also promote coordinated services through auto-connectivity and comparable notes, especially patient notes—an   additional Smart-Agility aspect for which EPIC scores high too. EPIC’s potential for providing Smart-Agile healthcare lies in its ability to quickly connect information and retrieve standardized data for comparative analysis and because it requires pre-determined data outcome measurements. <xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842005124">66</xref>, <xref ref-type="bibr" rid="ridm1842155900">46</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1842145244">48</xref><xref ref-type="bibr" rid="ridm1842142076">49</xref><xref ref-type="bibr" rid="ridm1842135740">50</xref><xref ref-type="bibr" rid="ridm1842130988">51</xref><xref ref-type="bibr" rid="ridm1842123788">52</xref><xref ref-type="bibr" rid="ridm1842098716">53</xref><xref ref-type="bibr" rid="ridm1842095260">54</xref><xref ref-type="bibr" rid="ridm1842091948">55</xref><xref ref-type="bibr" rid="ridm1842085252">56</xref><xref ref-type="bibr" rid="ridm1842079636">57</xref><xref ref-type="bibr" rid="ridm1842074812">58</xref><xref ref-type="bibr" rid="ridm1842073228">59</xref><xref ref-type="bibr" rid="ridm1842101452">60</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1842022116">62</xref><xref ref-type="bibr" rid="ridm1842016644">63</xref><xref ref-type="bibr" rid="ridm1842011964">64</xref><xref ref-type="bibr" rid="ridm1842009156">65</xref> EPIC is able to generate accurate and timely reports based on  requirements for entry of standardized data (e.g., EPIC “hard stops”*) <xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842145244">48</xref><xref ref-type="bibr" rid="ridm1842005124">66</xref>. These can be immediately queried for programmatic evaluation and modification research. Yet, EPIC allows for modification/inclusion of evidence-based prompts and hard stops for identifying and mandating standardized data entry. <xref ref-type="bibr" rid="ridm1842145244">48</xref></p>
        <p>However, there has been concern about a disadvantage of a monopoly or market dominance that locks purchasers into a monoculture and maintains antiquated programming and retards responsiveness,  de-confliction, flexibility, enhancement, and the ability to evolve—antithetical to the very essence of Smart Agility. <xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842145244">48</xref><xref ref-type="bibr" rid="ridm1842401836">10</xref> Nevertheless, EPIC provides “…the additional software layers for easy access to (standardized) clinical information and serves as an accessible, evaluable platform for collecting and analyzing clinical outcomes….”<xref ref-type="bibr" rid="ridm1842271812">28</xref> EPIC can be conformed to shepherd data entry and pre-identify errors and error patterns at the moment clinicians enter data. <xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842130988">51</xref><xref ref-type="bibr" rid="ridm1842123788">52</xref> Thus, data points can be identified and evaluated virtually in real time, almost immediately enhancing accuracy and quality of data as well as informing medical service adjustments. <xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842101452">60</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1842016644">63</xref><xref ref-type="bibr" rid="ridm1842011964">64</xref>, <xref ref-type="bibr" rid="ridm1842003972">67</xref><xref ref-type="bibr" rid="ridm1841998212">68</xref><xref ref-type="bibr" rid="ridm1841994756">69</xref><xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841982444">72</xref><xref ref-type="bibr" rid="ridm1841976396">73</xref><xref ref-type="bibr" rid="ridm1841971644">74</xref><xref ref-type="bibr" rid="ridm1841908908">75</xref><xref ref-type="bibr" rid="ridm1841904732">76</xref><xref ref-type="bibr" rid="ridm1841899116">77</xref><xref ref-type="bibr" rid="ridm1841894940">78</xref><xref ref-type="bibr" rid="ridm1841892780">79</xref>,</p>
        <p>A reported challenge was that EPIC is ill-suited for back-loading data and information in the standard format, which results in multiple and expensive  remediation efforts. <xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841885940">80</xref> Back-loading continues to be a chronic and long-term problem, resulting in maintenance and the attendant expense of supporting several different systems that EPIC was supposed to eliminate in the first place.<xref ref-type="bibr" rid="ridm1841885940">80</xref> Conversely, EPIC is easily able to capitalize on its standardized real-time workplace data entry of medical-condition-service-for-fee codes to identify patterns and practices.<xref ref-type="bibr" rid="ridm1841885940">80</xref> It permits non-intrusive, accurate, and virtually real-time identification for analyses that could continuously operate unnoticed in the background.<xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842142076">49</xref><xref ref-type="bibr" rid="ridm1842130988">51</xref><xref ref-type="bibr" rid="ridm1842098716">53</xref><xref ref-type="bibr" rid="ridm1841879892">82</xref></p>
        <p>EPIC’s standardized data-ready feature can be leveraged to track medical procedures and substantially reduce unplanned outcomes as well as facilitate    clinically-based decision support.<xref ref-type="bibr" rid="ridm1842155900">46</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841883852">81</xref> EPIC’s            front-end-back-end standardized data entry, and query and data report generator, have been validated to eliminate the expensive, repetitive loading of data into multiple different systems.<xref ref-type="bibr" rid="ridm1841879892">82</xref><xref ref-type="bibr" rid="ridm1841872620">83</xref></p>
        <p>EPIC also scores high in terms of the                    Smart-Agile aspects  of provision for the development of targeted automatic algorithms to inform and support cost-effective medical and organizational decisions while taking into account possible risks.<xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842262524">30</xref><xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842194636">44</xref> Smart-agile systems consider responsive knowledge management key to high-quality, efficient healthcare, and they can alert and trigger marshalling of a            substantial amount of comprehensive data to do so.<xref ref-type="bibr" rid="ridm1842401836">10</xref> Put differently, EPIC has shown the potential to support Smart-Agile healthcare through better              information that increases quality with earlier, more appropriate, and less expensive treatments.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1841868588">84</xref> Decision-makers can be enabled to make efficient and effective use of vastly increased amounts of data in modern information-driven healthcare industries. The capacity for more data in turn means more performance measures can be gauged. <xref ref-type="bibr" rid="ridm1842574324">1</xref> This means a higher probability that healthcare    organizations can quickly delivery the right products at the right time, with the right quality, and at the right price—the essence of Smart-Agile.<xref ref-type="bibr" rid="ridm1842574324">1</xref><xref ref-type="bibr" rid="ridm1841866068">85</xref><xref ref-type="bibr" rid="ridm1841861316">86</xref><xref ref-type="bibr" rid="ridm1841858148">87</xref> Furthermore, adoption of              Smart-Agile processes has been shown to direct service delivery toward a customer-oriented paradigm, which in turn supports agile decision-making in organizations, if not agility itself. <xref ref-type="bibr" rid="ridm1841854188">88</xref></p>
      </sec>
      <sec id="idm1841881868">
        <title>Technological Somnambulism</title>
        <p>Regarding technological constraints, EPIC fairs less well according to the Smart-Agile criterion of “quality.”<xref ref-type="bibr" rid="ridm1842306036">25</xref> Smart-Agile IT systems permit a degree of non-standardization in that customers/patients/stakeholders and their needs are non-standard with differing “preferences, personal characteristics, and conditions.”<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref> Then there are healthcare providers with differing backgrounds, professional roles, skills, training, and experience that must be accounted for.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref> Therefore, to be Smart-Agile, healthcare IT systems must have both novel and standardize inputs, though EPIC tends to favor  standardization.</p>
        <p>Hard-stop-enabled standardized data entry comes with a downside, namely, risk of reflexive and non-reflective technology-driven hypnosis and even sleepwalking.<xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841982444">72</xref><xref ref-type="bibr" rid="ridm1841845476">90</xref> EPIC suffers from issues surrounding all EHRs with meaningful use capabilities. Specifically, front-end data collection is shepherded, entailing overreliance on pre-determined (i.e., “canned”) forms and templates for information collection—as opposed to producing truly meaningful data.<xref ref-type="bibr" rid="ridm1842268068">29</xref> This may be further complicated by polished and                      slick-veneered electronic systems. This can be remedied by a dedicated team of medical experts, software designers and vendors updating and customizing forms and templates to capture relevant medical information throughout the medical care cycle—but those come at a steep price<xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1841770860">91</xref><xref ref-type="bibr" rid="ridm1842130988">51</xref> In this regard, a similar drawback with EPIC is that it does not permit entering more specific or different information<xref ref-type="bibr" rid="ridm1842271812">28</xref>, except through the incorporation of expensive add-ons that detract from its overall efficiency.<xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1841879892">82</xref><xref ref-type="bibr" rid="ridm1841769132">92</xref><xref ref-type="bibr" rid="ridm1841764092">93</xref></p>
        <p>In terms of EHR product development, because the EHR development cycle is regulated, and thus lengthy, it also is expensive—anathema to Smart-Agile healthcare IT systems aspect  <xref ref-type="bibr" rid="ridm1842427660">4</xref><xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842091948">55</xref><xref ref-type="bibr" rid="ridm1841971644">74</xref><xref ref-type="bibr" rid="ridm1841753652">96</xref><xref ref-type="bibr" rid="ridm1842209396">40</xref><xref ref-type="bibr" rid="ridm1842074812">58</xref><xref ref-type="bibr" rid="ridm1842011964">64</xref><xref ref-type="bibr" rid="ridm1841894940">78</xref><xref ref-type="bibr" rid="ridm1841892780">79</xref><xref ref-type="bibr" rid="ridm1841872620">83</xref><xref ref-type="bibr" rid="ridm1841764092">93</xref><xref ref-type="bibr" rid="ridm1841760564">94</xref><xref ref-type="bibr" rid="ridm1841755884">95</xref><xref ref-type="bibr" rid="ridm1841748036">97</xref>. Yet EPIC offers modifiable off-the-shelf packages that that keep costs relatively low and have the capability for                   continuous innovation and improvement in general. <xref ref-type="bibr" rid="ridm1842312660">27</xref> Nevertheless, those innovations do involve costly teams of experts and designers, and so they score low in terms of Smart-Agility healthcare IT systems<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><xref ref-type="bibr" rid="ridm1842574324">1</xref> It is probably no better or worse in this area than other meaningful-use EHRs.</p>
      </sec>
      <sec id="idm1841881508">
        <title>Time Commitments and Productivity</title>
        <p>This is another area where EPIC does not fare well according to Smart-Agile IT healthcare systems aspects; specifically, additional expense and work burden on end-users.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref> Several issues are unescapable with all meaningful-use EHRs that turn clinicians into data entry clerks. One is the additional time commitment of entering data loaded onto the already time-intensive commitments of clinical practice.<xref ref-type="bibr" rid="ridm1842135740">50</xref><xref ref-type="bibr" rid="ridm1842085252">56</xref><xref ref-type="bibr" rid="ridm1841879892">82</xref><xref ref-type="bibr" rid="ridm1841872620">83</xref><xref ref-type="bibr" rid="ridm1841849364">89</xref><xref ref-type="bibr" rid="ridm1841845476">90</xref><xref ref-type="bibr" rid="ridm1841748036">97</xref><sup> also see 27</sup><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841883852">81</xref> EPIC seems to be no different. Added documentation in EPIC also adds burden on healthcare providers.<xref ref-type="bibr" rid="ridm1841872620">83</xref><xref ref-type="bibr" rid="ridm1841743068">98</xref> However, the resulting seamless data analysis may be well worth the effort from providers’ perspectives. Nevertheless, there is that substantial “after hours’ time tax” to enter information.<xref ref-type="bibr" rid="ridm1842085252">56</xref><xref ref-type="bibr" rid="ridm1841872620">83</xref><xref ref-type="bibr" rid="ridm1841743068">98</xref><xref ref-type="bibr" rid="ridm1841741124">99</xref><xref ref-type="bibr" rid="ridm1841736156">100</xref><xref ref-type="bibr" rid="ridm1841732196">101</xref><xref ref-type="bibr" rid="ridm1841727804">102</xref></p>
        <p>Two, what really makes EPIC truly desirable for outcomes measurement, program evaluation, and research are its hard stops. <xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842009156">65</xref><xref ref-type="bibr" rid="ridm1841904732">76</xref><xref ref-type="bibr" rid="ridm1841753652">96</xref><xref ref-type="bibr" rid="ridm1841736156">100</xref><xref ref-type="bibr" rid="ridm1841732196">101</xref><xref ref-type="bibr" rid="ridm1841724348">103</xref><xref ref-type="bibr" rid="ridm1841721108">104</xref> However, they also pose a severe detraction or Achilles’ heel in that they disrupt smooth workflow and also result in end-use dissatisfaction.<xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841998212">68</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref> Nevertheless, it has been noted that medical providers’ productivity work volume, charges, and work relative to volume units actually increases with EPIC; the caveat is that it takes several months of a painful learning curve to realize increased productivity. <xref ref-type="bibr" rid="ridm1841883852">81</xref><xref ref-type="bibr" rid="ridm1841781804">105</xref><xref ref-type="bibr" rid="ridm1842016644">63</xref><xref ref-type="bibr" rid="ridm1841885940">80</xref><xref ref-type="bibr" rid="ridm1841872620">83</xref><xref ref-type="bibr" rid="ridm1841741124">99</xref><sup>100101</sup><xref ref-type="bibr" rid="ridm1841727804">102</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref></p>
        <sec id="idm1841879564">
          <title>Real-time Data Warehousing and (Patient-centered) Efficient Production of Outcome Measures</title>
          <p>Competitive agility, in accordance with Smart-Agility healthcare IT systems, is predicated on IT systems that are positioned “to produce, capture, store, process, and communicate.”<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><xref ref-type="bibr" rid="ridm1842306036">25</xref>** Therefore, EPIC excels on this particularly critical             Smart-Agility IT healthcare systems metric.</p>
          <p>EPIC excels when it comes to drawing on the vast warehouse of data it stores and generating reasonably accurate (and extremely timely) outcome measures, which is eponymously the essence of “meaningful use.” <xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841982444">72</xref><xref ref-type="bibr" rid="ridm1841845476">90</xref><xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842155900">46</xref><xref ref-type="bibr" rid="ridm1842142076">49</xref><xref ref-type="bibr" rid="ridm1842095260">54</xref><xref ref-type="bibr" rid="ridm1842091948">55</xref><xref ref-type="bibr" rid="ridm1842085252">56</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1842022116">62</xref><xref ref-type="bibr" rid="ridm1842003972">67</xref><xref ref-type="bibr" rid="ridm1841971644">74</xref><xref ref-type="bibr" rid="ridm1841894940">78</xref><xref ref-type="bibr" rid="ridm1841885940">80</xref><xref ref-type="bibr" rid="ridm1841039852">107</xref><xref ref-type="bibr" rid="ridm1841035532">108</xref><xref ref-type="bibr" rid="ridm1841032508">109</xref> EPIC has been shown to substantially decrease multi-center decision support systems and time-to-decision, and physician’s use of data to dramatically improve accurate diagnosis and treatment. <xref ref-type="bibr" rid="ridm1842142076">49</xref><xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841982444">72</xref> It has been shown that physicians using EPIC for data output substantially and geometrically improves accurate diagnosis; however, some of this was not possible without add-on programs that helped analyze the raw data that the back-end of EPIC produced.<xref ref-type="bibr" rid="ridm1841883852">81</xref><xref ref-type="bibr" rid="ridm1841849364">89</xref><xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841845476">90</xref><xref ref-type="bibr" rid="ridm1841727804">102</xref><xref ref-type="bibr" rid="ridm1841035532">108</xref><xref ref-type="bibr" rid="ridm1842142076">49</xref> There is substantial support for EPIC being the ideal front-end-to-back-end interface between required documentation and clinical research.<xref ref-type="bibr" rid="ridm1842681100">3</xref><xref ref-type="bibr" rid="ridm1842130988">51</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841879892">82</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841892780">79</xref><xref ref-type="bibr" rid="ridm1841039852">107</xref><xref ref-type="bibr" rid="ridm1841035532">108</xref><xref ref-type="bibr" rid="ridm1841026676">110</xref>.</p>
          <p>Another feature of IT systems that enable agility is that they provide secure, high-quality data exchange essential to efficient health care<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref>, which the literature clearly suggest EPIC provides. In this regard, EPIC’s capability in accordance with this Smart-Agile healthcare IT systems is remarkable; EPIC “overcomes the healthcare barriers involved with data-driven and analytical decision including but not limited to:           incomplete personal healthcare data, unconnected or silo’ed data, large amounts of unstructured data, and even paper-based records.”<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref> The literature suggests EPIC has a track record—per Smart-Agile IT systems criterion— of ‘high-quality, secure, compliance-driven, intra-operability enabled by healthcare experience and geared toward efficient change and process           management.’<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref> EPIC enhances big-data enabling of business intelligence (BI) as well as knowledge-management for the collection, analysis, and dissemination of substantial amounts of structured and unstructured data for quick actionable and accurate decisions.<xref ref-type="bibr" rid="ridm1841044316">106</xref> And “big data” promises yet-untapped potential of insights into miracle cures, disease etiology, waste prevention, and every imaginable realm of healthcare to include informing Smart-Agile               decisions.<xref ref-type="bibr" rid="ridm1842326628">22</xref>*</p>
        </sec>
      </sec>
      <sec id="idm1841880140">
        <title>Enhanced Patient Safety</title>
        <p>Critical to Smart-Agile healthcare IT systems is the “provision of informed seamless patient-centric for actionable healthcare delivery paramount of which is the maintenance of patient safety.”<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842199100">43</xref><xref ref-type="bibr" rid="ridm1842306036">25</xref><xref ref-type="bibr" rid="ridm1841854188">88</xref> EPIC’s ability to quickly and accurately derive outcome measures is critical in terms of efficient and timely identification of potentially deadly patient hazards and targeting those patients for intervention.<xref ref-type="bibr" rid="ridm1842142076">49</xref><xref ref-type="bibr" rid="ridm1842073228">59</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1841971644">74</xref><xref ref-type="bibr" rid="ridm1841908908">75</xref><xref ref-type="bibr" rid="ridm1841883852">81</xref><xref ref-type="bibr" rid="ridm1841748036">97</xref><xref ref-type="bibr" rid="ridm1841736156">100</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref><xref ref-type="bibr" rid="ridm1841039852">107</xref><xref ref-type="bibr" rid="ridm1841035532">108</xref><xref ref-type="bibr" rid="ridm1841022284">111</xref><xref ref-type="bibr" rid="ridm1841020700">112</xref><xref ref-type="bibr" rid="ridm1841014508">113</xref><xref ref-type="bibr" rid="ridm1841011988">114</xref><xref ref-type="bibr" rid="ridm1841009540">115</xref><xref ref-type="bibr" rid="ridm1841007020">116</xref><xref ref-type="bibr" rid="ridm1842079636">57</xref> EPIC is a powerful tool to monitor adherence to prescribing best practices, but only with rather expensive add-ons with which to conduct analyses and a lot of hard stops interfering with workflows.<xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1841883852">81</xref><xref ref-type="bibr" rid="ridm1841849364">89</xref><xref ref-type="bibr" rid="ridm1841000756">117</xref><xref ref-type="bibr" rid="ridm1841908908">75</xref><xref ref-type="bibr" rid="ridm1841899116">77</xref><xref ref-type="bibr" rid="ridm1841892780">79</xref></p>
        <p>EPIC facilitates the coordination of patient healthcare to promote safety and long-term wellness, while remaining cost-effective through comparable patient notes.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref><xref ref-type="bibr" rid="ridm1842209396">40</xref> And Smart-Agile healthcare IT systems lend themselves to the aspect of “development of tools to better real-time monitor processes and outcomes to include safety, and in particular for the healthcare industry, patient             safety.”<xref ref-type="bibr" rid="ridm1842401836">10</xref> EPIC’s ability to standardize and connect resources “accelerates patient recoveries, enhances evidence-based practices and less-expensive preventive medicine—and thus, provide Smart-Agile improved care.”<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842326628">22</xref></p>
      </sec>
      <sec id="idm1841879636">
        <title>Patient Tracking and Follow-up</title>
        <p>A critical cornerstone of Smart-Agile healthcare IT systems concept is systems integration, i.e.,                inter-operability and inter-connectivity that permits ease of follow-up in the interest of continuity of care and also safety. <xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><sup> also see 25</sup> EPIC’s ability to             accurately derive and report information in almost real time to identify patient safety risks also lends itself to excellent patient tracking, monitoring, and follow-up.<xref ref-type="bibr" rid="ridm1842271812">28</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842155900">46</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1841976396">73</xref><xref ref-type="bibr" rid="ridm1841760564">94</xref><xref ref-type="bibr" rid="ridm1841755884">95</xref><xref ref-type="bibr" rid="ridm1841039852">107</xref><xref ref-type="bibr" rid="ridm1841000756">117</xref> EPIC is an excellent system for electronically tracking patients and their procedures, and documenting complications, risks, and sources of unplanned outcomes.<xref ref-type="bibr" rid="ridm1842155900">46</xref> EPIC also provides an excellent data recording system for conducting inexpensive, continuous four-year longitudinal patient surveys; it also permits easy aggregation by type and level of complications, though this requires expensive add-on algorithms.<xref ref-type="bibr" rid="ridm1841000756">117</xref><xref ref-type="bibr" rid="ridm1841994756">69</xref> In this regard, EPIC also scores high on another Smart-Agile healthcare IT system criterion, service provision, including personalized medicine and the connectivity features to support that<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><xref ref-type="bibr" rid="ridm1842306036">25</xref>. </p>
      </sec>
      <sec id="idm1841828852">
        <title>End-user Satisfaction</title>
        <p>According to Smart-Agile IT healthcare systems, end-users’ satisfaction is critical because it relates to a large degree to stakeholder buy-in (as end-users are one group of stakeholders).<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref> Specifically, users’ satisfaction with their healthcare IT system is important because “healthcare organizations represent powerful stakeholders whose concern is high-quality healthcare provision and delivery, not learning or wrestling with IT.”<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref></p>
        <p>End-user satisfaction is one area where EPIC scores are mediocre or even low or failing; the range of physician average satisfaction rates are between                    50 – 75% depending on the particular EPIC feature. <xref ref-type="bibr" rid="ridm1842681100">3</xref><xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1841727804">102</xref><xref ref-type="bibr" rid="ridm1841721108">104</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref><xref ref-type="bibr" rid="ridm1841032508">109</xref><xref ref-type="bibr" rid="ridm1840997372">118</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref> One key feature that resulted in the most end-user dissatisfaction was EPIC’s “Reminder(s)”; they operate much like its hard stops in that they must be addressed before proceeding with workflow.<xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841849364">89</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref> This clearly detracts from EPIC’s usefulness in terms of preventive medicine and patient safety. Overburdening and overwhelming medical treatment providers with best practices advisories in large numbers generate scores of             complaints.<xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref> Marked improvement on end-user satisfaction was noted when limits were placed on Reminders.<xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841849364">89</xref> Nevertheless, Reminders significantly improve compliance among providers in terms of orders and rates of adherence to directive and documentation.<xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841985324">71</xref><xref ref-type="bibr" rid="ridm1841982444">72</xref> This may be why EPIC works better than other EHRs that use passive collection in terms of outcomes. But extreme dissatisfaction has been noted with it and results in less-than-optimal use of some key EPIC functions. One reason the end-users feel this way is that data entry for them is inefficient and too                          time-consuming.<xref ref-type="bibr" rid="ridm1842681100">3</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1842091948">55</xref><xref ref-type="bibr" rid="ridm1842016644">63</xref><xref ref-type="bibr" rid="ridm1841990076">70</xref><xref ref-type="bibr" rid="ridm1841904732">76</xref><xref ref-type="bibr" rid="ridm1841899116">77</xref><xref ref-type="bibr" rid="ridm1841892780">79</xref><xref ref-type="bibr" rid="ridm1841849364">89</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref><xref ref-type="bibr" rid="ridm1841026676">110</xref> Smart-Agile healthcare IT systems must be efficient to warrant their cost, and EPIC probably needs improvement regarding this end-user feature. Put differently, it needs to clearly demonstrate value-added in terms of time-consuming data entry.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842194636">44</xref></p>
      </sec>
      <sec id="idm1841829716">
        <title>Patient Involvement </title>
        <p>A critical aspect insinuated throughout                 Smart-Agile healthcare IT systems is patient involvement in their healthcare via IT systems—an area where EPIC has shown a track record and vast potential.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref> Specifically, Smart-Agile healthcare IT systems must involve patients as primary end-users (a.k.a.,              stakeholders).<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref> The promotion of patient-centric wellness involves the unified amalgamation of different IT delivery systems.</p>
        <p>EPIC’s connectivity and ability to electronically transmit real-time medical chart information securely over the Internet has vast potential regarding proactive integration of patients into the management of their own healthcare<xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1842252444">34</xref><xref ref-type="bibr" rid="ridm1842150572">47</xref>, even older non-tech-savvy patients.<xref ref-type="bibr" rid="ridm1841764092">93</xref> This can enable and empower patients to easily and smoothly transfer or upload images and documents from outside sources and physicians to shift their patient management to more virtual vs. less            face-to-face encounters.<xref ref-type="bibr" rid="ridm1842150572">47</xref></p>
        <p>According to Smart-Agile healthcare IT systems aspects, EPIC’s aim to consolidate processes and simplify, demystify, and automate business                practices—while involving patients in their              healthcare—creates and synchs a collaboration between patients as valued partners with providers.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref> As such, EPIC has the potential to involve both patients and providers as co-producers in Smart-Agile medical treatment, and this will alter the fundamental pattern of those interactions. </p>
        <p>Of course, all this requires a common (i.e., standardized) language that EPIC facilitates. And according to Smart-Agile healthcare IT systems  rationale, process orientation has been shown overall to support cost reductions, improve product quality and customer satisfaction, and decrease the production cycle time.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><xref ref-type="bibr" rid="ridm1841854188">88</xref></p>
      </sec>
      <sec id="idm1841829140">
        <title>Training</title>
        <p>The literature on Smart-Agile healthcare IT systems appears to understate ongoing training that must necessarily accompany dynamic IT systems. Thus it is considered non-critical<xref ref-type="bibr" rid="ridm1842306036">25</xref> Nevertheless, there has been identification in the EPIC literature of the essential need for ongoing training in terms of transitioning and exploiting EPIC’s potential to its fullest<xref ref-type="bibr" rid="ridm1842150572">47</xref><xref ref-type="bibr" rid="ridm1842073228">59</xref><xref ref-type="bibr" rid="ridm1842025716">61</xref><xref ref-type="bibr" rid="ridm1842016644">63</xref><xref ref-type="bibr" rid="ridm1841899116">77</xref><xref ref-type="bibr" rid="ridm1841721108">104</xref><xref ref-type="bibr" rid="ridm1841781804">105</xref><xref ref-type="bibr" rid="ridm1841032508">109</xref><xref ref-type="bibr" rid="ridm1840988372">121</xref><xref ref-type="bibr" rid="ridm1841885940">80</xref> Smart-Agile healthcare IT systems literature tends to view training as an additional expense and encumbrance to be avoided, as opposed to an investment in the future in terms of responsiveness and efficiency.<xref ref-type="bibr" rid="ridm1840994276">119</xref><xref ref-type="bibr" rid="ridm1840990316">120</xref><xref ref-type="bibr" rid="ridm1841892780">79</xref> Perhaps this is an area that the Smart-Agile IT systems researchers and proponents should reconsider as vital and revisit.</p>
      </sec>
      <sec id="idm1841830220">
        <title>Potential Use in Medical Education</title>
        <p>The Smart-Agile healthcare IT systems  proponents recognize that Smart-Agile systems     represent a platform from which to deliver healthcare training to healthcare professionals; this is considered a critical aspect.<xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842206012">41</xref><xref ref-type="bibr" rid="ridm1842194636">44</xref><xref ref-type="bibr" rid="ridm1842306036">25</xref><xref ref-type="bibr" rid="ridm1842301428">26</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref> EPIC also has potential as a tool for the delivery of medical training and education. <xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1842101452">60</xref><xref ref-type="bibr" rid="ridm1841872620">83</xref><xref ref-type="bibr" rid="ridm1841845476">90</xref><xref ref-type="bibr" rid="ridm1841755884">95</xref><xref ref-type="bibr" rid="ridm1841743068">98</xref><xref ref-type="bibr" rid="ridm1841781804">105</xref><xref ref-type="bibr" rid="ridm1841044316">106</xref><xref ref-type="bibr" rid="ridm1840988372">121</xref> However, EPIC’s standardized templates impose limits on documenting and dictation and thus detract from its potential for medical education in terms of extemporaneity.<xref ref-type="bibr" rid="ridm1841845476">90</xref><xref ref-type="bibr" rid="ridm1842312660">27</xref><xref ref-type="bibr" rid="ridm1842268068">29</xref><xref ref-type="bibr" rid="ridm1841743068">98</xref>. Hence, EPIC appears to adhere to the Smart-Agile healthcare IT systems criterion of encouraging the involvement of healthcare providers—the “powerful” stakeholders in healthcare organizations—in the IT systems as             generators of high-quality data and recipients of up-to-date healthcare training with the aim of ultimately improving patient care through informed analytic decision of best practices. <xref ref-type="bibr" rid="ridm1842401836">10</xref><xref ref-type="bibr" rid="ridm1842194636">44</xref><xref ref-type="bibr" rid="ridm1842214148">39</xref></p>
      </sec>
      <sec id="idm1841828924">
        <title>Report Card on EPIC in Terms of Smart-Agile Healthcare IT Systems</title>
        <p>The findings in the literature review in this article on EPIC’ meaningful use features graded in terms of Smart-Agile healthcare IT systems aspects are summarized in the “Report Card” that is depicted in <xref ref-type="table" rid="idm1841330764">Table 1</xref>. Scoring of themes was simple nominal presence or absence in terms of synthesized summary statements of meaningful use featuress with referenced citations in the literature. Nominal presence / absence                    avoids subjectivity that would be encountered with Ordinal – Ratio numeric scoring. Criticality was           determined according to the necessity / criticalness in terms of Smart-Agile aspects. Note: EPIC’s meaningful use features potential to meet or not meet Smart-Agility aspects were also counted as presence and absence respectively—not a subjective matter of degree.</p>
        <table-wrap id="idm1841330764">
          <label>Table 1.</label>
          <caption>
            <title> EPIC Report Card</title>
          </caption>
          <table rules="all" frame="box">
            <tbody>
              <tr>
                <td>Rating</td>
                <td>EPIC Meaningful Use Features</td>
                <td>Critical / Non-Critical</td>
              </tr>
              <tr>
                <td>+</td>
                <td>Standardized Data Collection</td>
                <td>C</td>
              </tr>
              <tr>
                <td>-</td>
                <td>Technological Somnambulism</td>
                <td>NC</td>
              </tr>
              <tr>
                <td>+</td>
                <td>Real-time Data Warehousing and (Patient-centered) Efficient Production of Outcome Measures</td>
                <td>C</td>
              </tr>
              <tr>
                <td>-</td>
                <td>Time Commitment and Productivity</td>
                <td>NC</td>
              </tr>
              <tr>
                <td>+</td>
                <td>Enhanced Patient Safety</td>
                <td>C</td>
              </tr>
              <tr>
                <td>+</td>
                <td>Patient Tracking / Follow-up and Continuity of Care</td>
                <td>C</td>
              </tr>
              <tr>
                <td>-</td>
                <td>End-user Satisfaction</td>
                <td>C</td>
              </tr>
              <tr>
                <td>+</td>
                <td>Patient Involvement</td>
                <td>C</td>
              </tr>
              <tr>
                <td>(+)</td>
                <td>(IT) Training</td>
                <td>NC</td>
              </tr>
              <tr>
                <td>+</td>
                <td>Potential Use for Medical Education</td>
                <td>C</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <p>(<xref ref-type="table" rid="idm1841330764">Table 1</xref>) depicts that, when EPIC is graded in terms of Smart-Agile healthcare IT aspects, EPIC’s meaningful-use components appear mediocre at best (7 out of 11), and fail at worst (6 out of 11). However, EPIC succeeds and excels on Smart-Agile healthcare IT systems aspects that are the most central, critical and valuable (7 out of 8) in terms of informing healthcare organizations’ decisions and their patients’ care, specifically: Standardized Data Collection / Connectivity, Real-Time Data Warehousing/Outcome Measures, Enhanced Patient Safety, Patient Tracking and Follow-up (Continuity of Care), Patient Involvement, and Potential Use in Medical Education. Also, this work highlighted an area that Smart-Agile healthcare systems should consider, namely, IT education.</p>
      </sec>
    </sec>
    <sec id="idm1841784476" sec-type="conclusions">
      <title>Conclusion</title>
      <p>This work reported a comprehensive                   best-practices literature review derived from                     peer-reviewed articles on “meaningful use” features of EPIC’s EHR system related to their potential to fulfill the Smart-Agile healthcare IT systems concept—that is, their ability to inform and enable agile healthcare organization decisions and patient care. As such, this work derived a presence-absence report card on EPIC’s ability to afford smart use and enhance Smart-Agility—the report card was mixed.</p>
      <p>This comparative review revealed that EPIC provides a rigorous front-end-to-back-end system for the rapid collection and inter-connected management of medical records information that lends itself to efficient reporting and informing agile management decisions. Thus, it truly has the ability to accurately inform              Smart-Agile organizational advancement, in particular for patient medical treatment and healthcare organizations in general.</p>
      <p>Nevertheless, that accuracy and rigor is achieved at a (hidden) cost, specifically, increased workloads on medical practitioners and various cross-team over-commitments that result in inefficiency, which in turn detracts from agility and is not smart use. The question in terms of agility is: At what point does the price exceed the benefit of agility sought, so that it is no longer a smart use investment?</p>
      <p>Researcher experience clearly suggests that EPIC can provide substantial raw data that can be further refined with add-on analytic tools,                         auto-algorithms, or hands-on user analyses. EPIC’s exacting and comprehensive (auto) interconnected data collection lends itself to nearly real-time provision of information to powerfully improve the accurate responsiveness and agility of healthcare organizations and medical treatment decisions.<xref ref-type="bibr" rid="ridm1842271812">28</xref></p>
      <p>Thus, EPIC has the unparalleled ability to augment agility in terms of enhancing patient safety and tweak treatment adjustments accordingly—through not only comprehensive inter-connected data but also limited and worthwhile reminders and hard-stops. Conversely, increased and unwarranted data entry and hard stop reminders are not smart use; they detract from agility in that this can cause extreme dissatisfaction in end-users as well as frustration, aggravation, and burn-out in busy medical practitioners.  </p>
      <p>Furthermore, used indiscriminately, EPICs standardization is not Smart-Agile nor contributes to agile practice and decisions. This is the flipside and danger of meaningful use systems, namely,                 Technological Somnambulism. Specifically, the computer is doing the leading and driving. Cognizant organizational decision makers and practitioners switch to auto-pilot and are just blindly along for the ride. Without analytically sharp decision-makers at all levels using the high-quality information EPIC culls to inform Smart-Agile practices, the computer becomes an end in itself rather than a means or tool to an agile end. EPIC does favor consistency and relationships where, if unguided by discerning and reflective medical insight, EPIC’s medical information could easily become vacuous and powerless, especially in terms of Smart Agility. </p>
      <p>   Nevertheless, EPIC’s most profound and                   yet-to-be-tapped benefit to users is as an IT teaching tool. Note, this is an feature overlooked in terms of smart and agile use, and should be included in any future discourses. EPIC has also shown great promise in terms of synergizing patient connectivity and            involvement in their own healthcare—which is an aspect of smart use and agility. </p>
      <p>The report card on EPIC is mixed. Yet it should be noted that Smart-Agility is an ideal. And all IT systems are imperfect at best. Nevertheless, as EPIC increasingly governs large swathes of EHR market shares and makes inroads into other IT markets that involve records, the challenge will be whether users can overcome its inflexibility and accommodate more aspects of Smart-Agile use. <xref ref-type="bibr" rid="ridm1842145244">48</xref> EPIC, like all meaningful use IT healthcare systems, has federally mandated features. Thus, another important question is how well EPIC’s competitors do in terms of smart use and agility and whether the ideal of the Smart-Agility concept is even a fair test for software never originally designed with this in mind. These considerations were not the province of this study but will be matters for future investigations.</p>
      <p><bold>*Note: </bold>A hard stop is a prompt that will not allow an operation to proceed without entering particular data in a standard and correct format.</p>
      <p><bold>**Note:</bold> This is variously referred to in the Smart-Agile literature as “portfolio management,” that is,                   Smart-Agile decisions based on valid and sufficient information derived from interoperability, stability, compressive-ness, and rigor, and continuously aimed at project operations in competitive and turbulent  situations to seize opportunities and advance healthcare organization goals. <xref ref-type="bibr" rid="ridm1841858148">87</xref></p>
    </sec>
    <sec id="idm1841782460">
      <title>Declarations</title>
      <sec id="idm1841782604">
        <title>Ethical Approval and Consent to Participate</title>
        <p>Non-applicable, this was a review of                   open-source documents and analyses of anonymous publically available data. </p>
      </sec>
    </sec>
    <sec id="idm1841783180">
      <title>Consent for Publication</title>
      <p>Yes.</p>
    </sec>
    <sec id="idm1841782172">
      <title>Availability of Data and Materials</title>
      <p>The “datasets” used and/or analyzed during the current study are available from the corresponding author on reasonable formal request. </p>
      <p>
        <bold>Funding</bold>
      </p>
      <p>Non-applicable, this research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.</p>
      <p>
        <bold>Authors’ Contribution</bold>
      </p>
      <p>Non-applicable, there is one sole Author.</p>
    </sec>
    <sec id="idm1841780660">
      <title>Corresponding author</title>
      <p>Reprints and correspondence should be addressed to the author at ralph.johnson@txsg.state.tx.us, or rjjohnson@mdanderson.org, UT-MDACC, Unit 429, 1515 Holcombe, Houston, Texas, 77030-400, U.S.A.                 (713-745-2207; 832-372-3511)</p>
    </sec>
  </body>
  <back>
    <ack>
      <p>The Author wishes to gratefully acknowledge             in-kind support of the Department of Lymphoma and Myeloma, UT-MD Anderson Cancer Center, Houston, TX. in the preparation of this manuscript. Also, the author thanks Ms. Deborah Davis for her encouragement in pursuing the subject matter and proof of concept and Ms. Aileen “Acey” Cho freelance-copy editor for              proofing and copyediting drafts. The opinions            expressed are solely those of the Author. </p>
    </ack>
    <ref-list>
      <ref id="ridm1842574324">
        <label>1.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Wu</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Barnes</surname>
            <given-names>D</given-names>
          </name>
          <article-title>A dynamic feedback model for partner selection in agile supply chains</article-title>
          <date>
            <year>2012</year>
          </date>
          <source>J Ops &amp; Prod Man;</source>
          <volume>32</volume>
          <issue>1</issue>
          <fpage>79</fpage>
          <lpage>103</lpage>
          <pub-id pub-id-type="doi">10.1108/01443571211195745</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842581172">
        <label>2.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Håkansson</surname>
            <given-names>H</given-names>
          </name>
          <name>
            <surname>Snehota</surname>
            <given-names>I</given-names>
          </name>
          <article-title>No business Is an Island: The Network Concept of business strategy</article-title>
          <date>
            <year>1989</year>
          </date>
          <source>Scan</source>
          <volume>22</volume>
          <fpage>187</fpage>
          <lpage>200</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842681100">
        <label>3.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Lin</surname>
            <given-names>C R</given-names>
          </name>
          <name>
            <surname>Chiu</surname>
            <given-names>H</given-names>
          </name>
          <name>
            <surname>Chu</surname>
            <given-names>P Y</given-names>
          </name>
          <article-title>Agility index in the supply chain</article-title>
          <date>
            <year>2006</year>
          </date>
          <source>Int J of Prod Econ:</source>
          <volume>100</volume>
          <issue>2</issue>
          <fpage>285</fpage>
          <lpage>299</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842427660">
        <label>4.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Christopher</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Lee</surname>
            <given-names>H</given-names>
          </name>
          <article-title>Mitigating supply chain risk through improved confidence.Int</article-title>
          <source>J PhysDist&amp; Log Man.2004:</source>
          <volume>34</volume>
          <fpage>388</fpage>
          <lpage>396</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842433852">
        <label>5.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Christopher</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Peck</surname>
            <given-names>H</given-names>
          </name>
          <article-title>Building the resilient supply chain.Int Log Man</article-title>
          <date>
            <year>2004</year>
          </date>
          <volume>15</volume>
          <fpage>1</fpage>
          <lpage>13</lpage>
          <pub-id pub-id-type="doi">10.1108/09574090410700275</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842417148">
        <label>6.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Christopher</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Towill</surname>
            <given-names>D</given-names>
          </name>
          <article-title>Supply Chain Migration From Lean and Functional to Agile and Customised.Sup Chain</article-title>
          <date>
            <year>2000</year>
          </date>
          <source>Man-Int J</source>
          <volume>5</volume>
          <fpage>206</fpage>
          <lpage>213</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842414412">
        <label>7.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kleindorfer</surname>
            <given-names>P R</given-names>
          </name>
          <name>
            <surname>WassenhouseLN</surname>
            <given-names>Van</given-names>
          </name>
          <article-title>Managing the risk in the global supply chain in Gantignon H and Kimberly JR (eds),The INSEAD-Wharton Alliance on Globalization: Strategies for Building Successful Global Business,Cambridge</article-title>
          <date>
            <year>2004</year>
          </date>
          <fpage>288</fpage>
          <lpage>331</lpage>
          <publisher-name>University Press</publisher-name>
          <publisher-loc>London</publisher-loc>
        </mixed-citation>
      </ref>
      <ref id="ridm1842403636">
        <label>8.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Prater</surname>
            <given-names>E</given-names>
          </name>
          <name>
            <surname>Biehl</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Smith</surname>
            <given-names>M</given-names>
          </name>
          <date>
            <year>2001</year>
          </date>
          <chapter-title>International Supply Chain Agility—Tradeoffs between Flexibility and Uncertainty.Int J Ops &amp; Prod Man.:</chapter-title>
          <volume>21</volume>
          <fpage>1</fpage>
          <lpage>30</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842401836">
        <label>10.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <article-title>International Supply Chain Agility—Tradeoffs between Flexibility and Uncertainty</article-title>
        </mixed-citation>
      </ref>
      <ref id="ridm1842396652">
        <label>9.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Banihashemi</surname>
            <given-names>S A</given-names>
          </name>
          <name>
            <surname>Ah</surname>
            <given-names>Sarani</given-names>
          </name>
          <article-title>Assessment of organizational agility in cement industry</article-title>
          <date>
            <year>2012</year>
          </date>
          <source>Africa J Bus Man</source>
          <volume>6</volume>
          <issue>27</issue>
          <fpage>8055</fpage>
          <lpage>8064</lpage>
          <pub-id pub-id-type="doi">10.5897/AJBM11.2124</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842375716">
        <label>10.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Demirkan</surname>
            <given-names>H</given-names>
          </name>
          <article-title>Smart healthcare systems framework: More service oriented, instrumented</article-title>
          <date>
            <year>2013</year>
          </date>
          <chapter-title>interconnected and intelligent,”IEEE IT Professional</chapter-title>
          <fpage>38</fpage>
          <lpage>45</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842371468">
        <label>11.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Tolf</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Nystrom</surname>
            <given-names>M E</given-names>
          </name>
          <name>
            <surname>Tishelman</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Brommels</surname>
            <given-names>M</given-names>
          </name>
          <article-title>Agile, a guiding principle for health care improvement?Int J Health Care Qual Assur:</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>28</volume>
          <issue>5</issue>
          <fpage>468</fpage>
          <lpage>93</lpage>
          <pub-id pub-id-type="doi">10.1108/IJHCQA-04-2014-0044</pub-id>
          <pub-id pub-id-type="pmid">26020429</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842370316">
        <label>12.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Sheffi</surname>
            <given-names>Y</given-names>
          </name>
          <article-title>Demand, variability, and supply chain flexibility</article-title>
          <chapter-title>in Prockl G (ed.) Contributions in Logistics, University of Nurnberg</chapter-title>
          <publisher-loc>Nurnberg</publisher-loc>
        </mixed-citation>
      </ref>
      <ref id="ridm1842366212">
        <label>13.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Swarfford</surname>
            <given-names>P M</given-names>
          </name>
          <name>
            <surname>Ghosh</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Murthy</surname>
            <given-names>N</given-names>
          </name>
          <article-title>A framework for assessing value chain agility</article-title>
          <date>
            <year>2006</year>
          </date>
          <source>Int J Ops and Prod Man</source>
          <volume>26</volume>
          <issue>2</issue>
          <fpage>118</fpage>
          <lpage>40</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842355684">
        <label>14.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Jain</surname>
            <given-names>V</given-names>
          </name>
          <name>
            <surname>Benyoucef</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Deshmukh</surname>
            <given-names/>
          </name>
          <article-title>A balanced approach to building agile supply chains,Int</article-title>
          <date>
            <year>2008</year>
          </date>
          <source>J PhysDist&amp; Log Man</source>
          <volume>46</volume>
          <issue>23</issue>
          <fpage>6649</fpage>
          <lpage>77</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842354028">
        <label>15.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Li</surname>
            <given-names>X</given-names>
          </name>
          <name>
            <surname>Chuang</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Goldsby</surname>
            <given-names>T J</given-names>
          </name>
          <name>
            <surname>Holsapple</surname>
            <given-names>C W</given-names>
          </name>
          <article-title>A unified model of supply chain partnering under limited evaluation resources.Int</article-title>
          <date>
            <year>2008</year>
          </date>
          <volume>20</volume>
          <issue>6</issue>
          <fpage>675</fpage>
          <lpage>91</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842347332">
        <label>16.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Charles</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Lauras</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>L</surname>
            <given-names>Van Wassen</given-names>
          </name>
          <article-title>A model to define and assess the agility of supply chains: Building on humanitarian experience.Int J PhysDistand Log Man</article-title>
          <date>
            <year>2010</year>
          </date>
          <volume>40</volume>
          <issue>8</issue>
          <fpage>10</fpage>
          <lpage>1108</lpage>
          <publisher-loc>Emerald</publisher-loc>
        </mixed-citation>
      </ref>
      <ref id="ridm1842344236">
        <label>17.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Slack</surname>
            <given-names>N</given-names>
          </name>
          <article-title>The flexibility of manufacturing systems,Int</article-title>
          <date>
            <year>2005</year>
          </date>
          <source>J Ops &amp; Prod Man</source>
          <volume>25</volume>
          <issue>12</issue>
          <fpage>1190</fpage>
          <lpage>200</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842357700">
        <label>18.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Yusuf</surname>
            <given-names>Y Y</given-names>
          </name>
          <name>
            <surname>Sarhadi</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Gunasekaran</surname>
            <given-names>A</given-names>
          </name>
          <article-title>Agile manufacturing: the drivers, concepts and attributes,Int J Prod Econ</article-title>
          <date>
            <year>1999</year>
          </date>
          <source>62 Nos</source>
          <volume>1</volume>
          <fpage>33</fpage>
          <lpage>43</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842335628">
        <label>19.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Sharifi</surname>
            <given-names>H</given-names>
          </name>
          <name>
            <surname>Zhang</surname>
            <given-names>Z</given-names>
          </name>
          <article-title>A methodology for achieving agility in manufacturing organisations: An introduction,Int J Prod Econ:</article-title>
          <date>
            <year>1999</year>
          </date>
          <volume>62</volume>
          <fpage>7</fpage>
          <lpage>22</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842332532">
        <label>20.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Giachetti</surname>
            <given-names>R E</given-names>
          </name>
          <name>
            <surname>Martinez</surname>
            <given-names>L D</given-names>
          </name>
          <name>
            <surname>Saenz</surname>
            <given-names>O A</given-names>
          </name>
          <name>
            <surname>Chen</surname>
            <given-names>C S</given-names>
          </name>
          <article-title>Analysis of the structural measures of flexibility and agility using a measurement theoretical framework,Int</article-title>
          <date>
            <year>2003</year>
          </date>
          <source>J Prod Econ:</source>
          <volume>86</volume>
          <issue>1</issue>
          <fpage>47</fpage>
          <lpage>62</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842329940">
        <label>21.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Sorkin</surname>
            <given-names>A</given-names>
          </name>
          <article-title>When unequals try to merge as equals.New York Times</article-title>
          <date>
            <year>2007</year>
          </date>
          <publisher-name>February</publisher-name>
        </mixed-citation>
      </ref>
      <ref id="ridm1842326628">
        <label>22.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Nambiar</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Sethi</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Bharwaj</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Varghese</surname>
            <given-names>R</given-names>
          </name>
          <article-title>A look at challenges and opportunities of Big Data Analytics</article-title>
          <date>
            <year>2013</year>
          </date>
          <chapter-title>in healthcare.IEEE International Conference on Big Data:</chapter-title>
        </mixed-citation>
      </ref>
      <ref id="ridm1842323604">
        <label>23.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Okongwu</surname>
            <given-names>U</given-names>
          </name>
          <name>
            <surname>Lauras</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Humez</surname>
            <given-names>V</given-names>
          </name>
          <name>
            <surname>Dupont</surname>
            <given-names>L</given-names>
          </name>
          <article-title>A decision support system for optimizing order production fulfillment.Production Planning and Control:</article-title>
          <date>
            <year>2012</year>
          </date>
        </mixed-citation>
      </ref>
      <ref id="ridm1842311004">
        <label>24.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Luo</surname>
            <given-names>X</given-names>
          </name>
          <name>
            <surname>Rosenberg</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Barnes</surname>
            <given-names>P S</given-names>
          </name>
          <article-title>Supplier selection in agile supply chains: An information processing model and an illustration</article-title>
          <date>
            <year>2009</year>
          </date>
          <source>J Purchas &amp; Suppl</source>
          <volume>15</volume>
          <issue>4</issue>
          <fpage>249</fpage>
          <lpage>62</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842306036">
        <label>25.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Linkevics</surname>
            <given-names>G</given-names>
          </name>
          <name>
            <surname>Sukovskis</surname>
            <given-names/>
          </name>
          <date>
            <year>2015</year>
          </date>
          <source>Evaluation of the agility of the organization.App Computer Sys:</source>
          <volume>18</volume>
          <fpage>21</fpage>
          <lpage>26</lpage>
          <pub-id pub-id-type="doi">10.1515/acss-2015-0015.https://www.researchgate.net/publication/297726066_Evaluation_of_the_Agility_Level_of_the_Organization</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842301428">
        <label>26.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Pipe</surname>
            <given-names>T B</given-names>
          </name>
          <name>
            <surname>Buchda</surname>
            <given-names>V L</given-names>
          </name>
          <name>
            <surname>Launder</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Hudak</surname>
            <given-names>B</given-names>
          </name>
          <article-title>Building personal and professional resources of resilience and agility in the healthcare workplace.Stress Health</article-title>
          <date>
            <year>2012</year>
          </date>
          <chapter-title>Feb;28(1): 11-22. doi: 10.1002/smi.1396. Epub</chapter-title>
          <volume>13</volume>
          <fpage>22259154</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.1002/smi.1396</pub-id>
          <pub-id pub-id-type="pmid">22259154</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842312660">
        <label>27.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Makam</surname>
            <given-names>A N</given-names>
          </name>
          <name>
            <surname>Lanham</surname>
            <given-names>H J</given-names>
          </name>
          <name>
            <surname>Batchelor</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Samal</surname>
            <given-names>L</given-names>
          </name>
          <article-title>Use and satisfaction with key functions of a common commercial electronic health record: A survey of primary care providers.BMC Med Inform Decision Making:</article-title>
          <date>
            <year>2013</year>
          </date>
          <volume>13</volume>
          <fpage>10</fpage>
          <lpage>1186</lpage>
          <pub-id pub-id-type="doi">10.1186/1472-6947-13-86</pub-id>
          <pub-id pub-id-type="pmid">24070335</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842271812">
        <label>28.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Katzan</surname>
            <given-names>I</given-names>
          </name>
          <name>
            <surname>Speck</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Dopler</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Urchek</surname>
            <given-names>J</given-names>
          </name>
          <article-title>The Knowledge Program: An innovative, comprehensive, electronic capture system and warehouse.AMIA</article-title>
          <date>
            <year>2011</year>
          </date>
          <chapter-title>AnnSympProc. 683-92. Epub</chapter-title>
          <fpage>22195124</fpage>
          <pub-id pub-id-type="pmid">22195124</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842268068">
        <label>29.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Carberry</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Landman</surname>
            <given-names>Z</given-names>
          </name>
          <name>
            <surname>Xie</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Feeley</surname>
            <given-names>T</given-names>
          </name>
          <article-title>Incorporating longitudinal pediatric-centered outcome measurement into the clinical workflow using a commercial electronic health record: A step toward increasing value for the patient.J Am Med Inform Ass:</article-title>
          <date>
            <year>2016</year>
          </date>
          <fpage>10</fpage>
          <lpage>1093</lpage>
          <pub-id pub-id-type="doi">10.1093/jamia/ocv125</pub-id>
          <pub-id pub-id-type="pmid">26377989</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842262524">
        <label>30.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Porter</surname>
            <given-names>M E</given-names>
          </name>
          <name>
            <surname>Teisberg</surname>
            <given-names>E</given-names>
          </name>
          <article-title>Redefining Health Care. Boston,MA:Harvard BusinessPublishing</article-title>
          <date>
            <year>2006</year>
          </date>
          <fpage>20</fpage>
          <lpage>20060502</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842261156">
        <label>31.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Tierney</surname>
            <given-names>W M</given-names>
          </name>
          <article-title>Improving clinical decisions and outcomes with information: A review.Int J Med Inform</article-title>
          <date>
            <year>2001</year>
          </date>
          <volume>62</volume>
          <fpage>1</fpage>
          <lpage>9</lpage>
          <pub-id pub-id-type="doi">10.1016/s1386-5056(01)00127-7https://www.sciencedirect.com/science/article/abs/pii/S1386505601001277?via%3Dihub</pub-id>
          <pub-id pub-id-type="pmid">11340002</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842256764">
        <label>32.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Blumenthal</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Tavenner</surname>
            <given-names>M</given-names>
          </name>
          <article-title>The meaningful use regulation for electronic health records.NEnglJ</article-title>
          <date>
            <year>2010</year>
          </date>
          <source>Med:</source>
          <volume>363</volume>
          <fpage>501</fpage>
          <lpage>504</lpage>
          <pub-id pub-id-type="doi">10.1056/NEJMp1006114</pub-id>
          <pub-id pub-id-type="pmid">20647183</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842253020">
        <label>33.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>CfMM</surname>
            <given-names>Services</given-names>
          </name>
          <article-title>EHR Incentive Program [online]. Available athttp://www.cms.gov/ehrincentiveprograms</article-title>
        </mixed-citation>
      </ref>
      <ref id="ridm1842252444">
        <label>34.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Gerber</surname>
            <given-names>D E</given-names>
          </name>
          <name>
            <surname>Lacetti</surname>
            <given-names>A L</given-names>
          </name>
          <name>
            <surname>Beibei</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Jingsheng</surname>
            <given-names>Y</given-names>
          </name>
          <article-title>Predictors and intensity of online access to electronic medical records among patients with cancer.JOncPract:</article-title>
          <date>
            <year>2014</year>
          </date>
          <chapter-title>PMID: 25006222 PMCID: PMC4161732 DOI:</chapter-title>
          <pub-id pub-id-type="pmid">25006222</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842279948">
        <label>35.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Ferris</surname>
            <given-names>N</given-names>
          </name>
          <article-title>Meaningful Use” of electronic health records.Health</article-title>
          <date>
            <year>2010</year>
          </date>
        </mixed-citation>
      </ref>
      <ref id="ridm1842276636">
        <label>36.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <article-title>Epic Electronic Health Record [Computer software]</article-title>
          <publisher-loc>Madison, WI: Epic; Madison, WI</publisher-loc>
        </mixed-citation>
      </ref>
      <ref id="ridm1842217100">
        <label>37.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Roth</surname>
            <given-names>M</given-names>
          </name>
          <article-title>In EMR market share wars, Epic and Cerner triumph yet again. Hlth Ldrs</article-title>
          <date>
            <year>2019</year>
          </date>
        </mixed-citation>
      </ref>
      <ref id="ridm1842216020">
        <label>38.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Johnson</surname>
            <given-names>R J</given-names>
          </name>
          <article-title>A Comprehensive Review of an Electronic Health Record System Soon to Assume Market Ascendancy: EPIC®.J Healthcare Comm</article-title>
          <fpage>10</fpage>
          <lpage>4172</lpage>
          <publisher-loc>DOI:</publisher-loc>
          <pub-id pub-id-type="doi">10.4172/2472-1654.100036.https://healthcare-communications.imedpub.com/a-comprehensive-review-of-an-electronic-health-record-system-soon-to-assume-market-ascendancy-epic.php?aid=17222,1:</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842214148">
        <label>39.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Izza</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Imache</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Vincent</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Lounis</surname>
            <given-names>Y</given-names>
          </name>
          <date>
            <year>2013</year>
          </date>
          <chapter-title>An Approach for the Evaluation of the Agility in the Context of Enterprise Interoperability in Mertins K, Ruggaber R, Popplewell K, and Xu X(eds.)EnterpriseInteroperabilityIII:NewChallenges and IndustrialApproaches:New York,NY;Springer Publications,doi:</chapter-title>
          <fpage>10</fpage>
          <lpage>1007</lpage>
          <pub-id pub-id-type="doi">10.1007/978-1-84800-221-0</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842209396">
        <label>40.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Strauss</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>J</surname>
            <given-names/>
          </name>
          <chapter-title>Corbin.Basics of Qualitative Research – Techniques and Procedures for Developing Grounded Theory, 4thed., London, Sage Publications: 2014. ISBN-13: 9781412997461 9781483315683 ISBN-10:</chapter-title>
          <fpage>1412997461</fpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842206012">
        <label>41.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Glaser</surname>
            <given-names>B G</given-names>
          </name>
          <article-title>and Strauss AL.The Discovery of Grounded Theory: Strategies for Qualitative Research. Aldine Transaction;</article-title>
          <date>
            <year>1967</year>
          </date>
          <publisher-loc>New Brunswick</publisher-loc>
        </mixed-citation>
      </ref>
      <ref id="ridm1842202772">
        <label>42.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Ramalho</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Adams</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Huggard</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Hoare</surname>
            <given-names>K</given-names>
          </name>
          <article-title>Literature review and constructivist grounded theory methodology.Forum Qual Soc Res</article-title>
          <date>
            <year>2015</year>
          </date>
          <fpage>16</fpage>
          <lpage>3</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1842199100">
        <label>43.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Liberati</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Altman</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Tetzlaff</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Mulrow</surname>
            <given-names>C</given-names>
          </name>
          <article-title>The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration.BMJ</article-title>
          <date>
            <year>2009</year>
          </date>
        </mixed-citation>
      </ref>
      <ref id="ridm1842194636">
        <label>44.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Liberati</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Altman</surname>
            <given-names>D G</given-names>
          </name>
          <name>
            <surname>Tetzlaff</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Mulrow</surname>
            <given-names>C</given-names>
          </name>
          <article-title>The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration.J Clin Epidemiol</article-title>
          <date>
            <year>2009</year>
          </date>
          <chapter-title>Oct;62(10): e1-34. doi: 10.1016/j.jclinepi.2009.06.006. Epub</chapter-title>
          <volume>23</volume>
          <fpage>19631507</fpage>
          <lpage>0895</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jclinepi.2009.06.006</pub-id>
          <pub-id pub-id-type="pmid">19631507https://linkinghub.elsevier.com/retrieve/pii/S0895-4356(09)00180-2</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842188948">
        <label>45.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Moher</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Shamseer</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Clarke</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Ghersi</surname>
            <given-names>D</given-names>
          </name>
          <article-title>Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P)</article-title>
          <date>
            <year>2015</year>
          </date>
          <source>statement.Syst Rev.;</source>
          <volume>4</volume>
          <fpage>10</fpage>
          <lpage>1186</lpage>
          <pub-id pub-id-type="doi">10.1186/2046-4053-4-1</pub-id>
          <pub-id pub-id-type="pmid">25554246</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842155900">
        <label>46.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>DeBoer</surname>
            <given-names>E M</given-names>
          </name>
          <name>
            <surname>Prager</surname>
            <given-names>J D</given-names>
          </name>
          <name>
            <surname>Kerby</surname>
            <given-names>G S</given-names>
          </name>
          <name>
            <surname>Stillwell</surname>
            <given-names>P C</given-names>
          </name>
          <article-title>Measuring pediatric bronchoscopy outcomes using Electronic Medical Record.Ann AmThoracSoc:</article-title>
          <date>
            <year>2016</year>
          </date>
          <volume>27</volume>
          <fpage>10</fpage>
          <lpage>1513</lpage>
          <pub-id pub-id-type="doi">10.1513/AnnalsATS.201509-576OC</pub-id>
          <pub-id pub-id-type="pmid">26816220</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842150572">
        <label>47.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Bornstein</surname>
            <given-names>S</given-names>
          </name>
          <article-title>An integrated EHR at Northern California Kaiser-Permanente.App Clin Inform:</article-title>
          <date>
            <year>2012</year>
          </date>
          <volume>3</volume>
          <issue>3</issue>
          <fpage>318</fpage>
          <lpage>25</lpage>
          <pub-id pub-id-type="doi">10.4338/ACI-2012-03-RA-0006</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842145244">
        <label>48.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Koppel</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Lehmann</surname>
            <given-names>C U</given-names>
          </name>
          <article-title>Implications of an emerging EHR monoculture for hospitals and healthcare systems.Am Med Inform Assoc:</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>22</volume>
          <issue>2</issue>
          <fpage>465</fpage>
          <lpage>71</lpage>
          <pub-id pub-id-type="doi">10.1136/amiajnl-2014-003023</pub-id>
          <pub-id pub-id-type="pmid">25342181</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842142076">
        <label>49.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Grigoryan</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Zaroob</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Wang</surname>
            <given-names>H</given-names>
          </name>
          <name>
            <surname>Trautner</surname>
            <given-names>B W</given-names>
          </name>
          <article-title>Low concordance with guidelines for treatment of acute cystitis in primary care.Open Forum Infect Dis</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>2</volume>
          <issue>4</issue>
          <fpage>10</fpage>
          <lpage>1093</lpage>
          <pub-id pub-id-type="doi">10.1093/ofid/ofv159</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842135740">
        <label>50.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Lindholm</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Adsit</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Bain</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Reber</surname>
            <given-names>P M</given-names>
          </name>
          <article-title>A demonstration project for using the electronic health record to identify and treat tobacco users.WMJ:</article-title>
          <date>
            <year>2010</year>
          </date>
          <volume>109</volume>
          <issue>6</issue>
          <fpage>335</fpage>
          <lpage>40</lpage>
          <publisher-name>PMCID:</publisher-name>
        </mixed-citation>
      </ref>
      <ref id="ridm1842130988">
        <label>51.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Bellon</surname>
            <given-names>J E</given-names>
          </name>
          <name>
            <surname>Stevans</surname>
            <given-names>J M</given-names>
          </name>
          <name>
            <surname>Cohen</surname>
            <given-names>S M</given-names>
          </name>
          <name>
            <surname>James</surname>
            <given-names>AE 3rd</given-names>
          </name>
          <article-title>Comparing advanced practice providers and physicians as providers of e-visits.TelemedJ E Health:</article-title>
          <date>
            <year>2015</year>
          </date>
          <chapter-title>doi: 10.1089/tmj.2014.0248. Epub</chapter-title>
          <volume>21</volume>
          <issue>12</issue>
          <fpage>1019</fpage>
          <lpage>26</lpage>
          <pub-id pub-id-type="doi">10.1089/tmj.2014.0248</pub-id>
          <pub-id pub-id-type="pmid">26161623</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842123788">
        <label>52.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Beck</surname>
            <given-names>J D</given-names>
          </name>
          <name>
            <surname>Deegan</surname>
            <given-names>J H</given-names>
          </name>
          <name>
            <surname>Riehl</surname>
            <given-names>J T</given-names>
          </name>
          <name>
            <surname>Klena</surname>
            <given-names>J C</given-names>
          </name>
          <article-title>Incidence of scapholunate ligament dissociation in patients with aspiration-confirmed gout.J Hand Surg Am:</article-title>
          <date>
            <year>2010</year>
          </date>
          <chapter-title>10.1016/j.jhsa.2010.08.009. Epub</chapter-title>
          <volume>35</volume>
          <issue>12</issue>
          <fpage>1938</fpage>
          <lpage>42</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jhsa.2010.08.009</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842098716">
        <label>53.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Stirling</surname><given-names>A</given-names></name><name><surname>Tubb</surname><given-names>T</given-names></name><name><surname>Reiff</surname><given-names>E S</given-names></name><name><surname>Grotegut</surname><given-names>C A</given-names></name><article-title>Identified themes of interactive visualizations overlayed onto EHR data: an example of improving birth center operating room efficiency.J Am Med Inform Assoc.2020 Mar pii:</article-title>
ocaa016. doi:



<pub-id pub-id-type="pii">ocaa016</pub-id></mixed-citation>
      </ref>
      <ref id="ridm1842095260">
        <label>54.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Peticolas</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Khairat</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Seashore</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Law</surname>
            <given-names>J</given-names>
          </name>
          <article-title>Physician-Led EHR Customization Tracking Assessments for Pediatric Patients with Turner Syndrome.Stud HealthTechnol Inform</article-title>
          <date>
            <year>2019</year>
          </date>
          <fpage>262</fpage>
          <lpage>276</lpage>
          <pub-id pub-id-type="doi">10.3233/SHTI190072</pub-id>
          <pub-id pub-id-type="pmid">31349321http://ebooks.iospress.nl/publication/51734</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842091948">
        <label>55.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Lewinski</surname>
            <given-names>A A</given-names>
          </name>
          <name>
            <surname>Drake</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Shaw</surname>
            <given-names>R J</given-names>
          </name>
          <name>
            <surname>Jackson</surname>
            <given-names>G L</given-names>
          </name>
          <article-title>Bridging the integration gap between patient-generated blood glucose data and electronic health records.Stud Health Technol Inform</article-title>
          <date>
            <year>2019</year>
          </date>
          <volume>4</volume>
          <fpage>276</fpage>
          <lpage>279</lpage>
          <pub-id pub-id-type="doi">10.3233/SHTI190072</pub-id>
          <pub-id pub-id-type="pmid">31349321https://academic.oup.com/jamia/article/26/7/667/5476183</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842085252">
        <label>56.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Fixen</surname><given-names>D R</given-names></name><name><surname>Linnebur</surname><given-names>S A</given-names></name><name><surname>Parnes</surname><given-names>B L</given-names></name><name><surname>Vejar</surname><given-names>M V</given-names></name><article-title>Development and economic evaluation of a pharmacist-provided chronic care management service in an ambulatory care geriatrics clinic.Am J Health Syst Pharm</article-title><date><year>2018</year></date><volume>75</volume><issue>22</issue><fpage>1805</fpage><lpage>1811</lpage><publisher-name>Epub</publisher-name>
PMID: 30104259.https://academic.oup.com/ajhp/article-abstract/75/22/1805/5220686?redirectedFrom=fulltext



<pub-id pub-id-type="doi">10.2146/ajhp170723</pub-id><pub-id pub-id-type="pmid">30104259.https://academic.oup.com/ajhp/article-abstract/75/22/1805/5220686?redirectedFrom=fulltext</pub-id></mixed-citation>
      </ref>
      <ref id="ridm1842079636">
        <label>57.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Sanelli-Russo</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Folkers</surname>
            <given-names>K M</given-names>
          </name>
          <name>
            <surname>Sakolsky</surname>
            <given-names>W</given-names>
          </name>
          <name>
            <surname>Fins</surname>
            <given-names>J J</given-names>
          </name>
          <article-title>Meaningful Use of Electronic Health Records for Quality Assessment and Review of Clinical Ethics Consultation.J Clin Ethics</article-title>
          <date>
            <year>2018</year>
          </date>
          <volume>29</volume>
          <issue>1</issue>
          <fpage>52</fpage>
          <lpage>61</lpage>
          <pub-id pub-id-type="pmid">29565797</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842074812">
        <label>58.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Mansour</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Master</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Automating Quality Oncology Practice Initiative Quality Measure NHL78a.JCO Clin Cancer Inform</article-title>
          <date>
            <year>2017</year>
          </date>
          <chapter-title>Nov;1: 1-6. doi: 10.1200/CCI.17.00038. PMID:</chapter-title>
          <fpage>30657389</fpage>
          <pub-id pub-id-type="doi">10.1200/CCI.17.00038</pub-id>
          <pub-id pub-id-type="pmid">30657389</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842073228">
        <label>59.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Dusek</surname>
            <given-names>J A</given-names>
          </name>
          <name>
            <surname>Griffin</surname>
            <given-names>K H</given-names>
          </name>
          <name>
            <surname>Finch</surname>
            <given-names>M D</given-names>
          </name>
          <name>
            <surname>Rivard</surname>
            <given-names>R L</given-names>
          </name>
          <date>
            <year>2018</year>
          </date>
          <chapter-title>Cost Savings from Reducing Pain Through the Delivery of Integrative Medicine Program to Hospitalized Patients.J Altern Complement Med. 2018 Jun;24(6): 557-563. doi: 10.1089/acm.2017.0203. Epub</chapter-title>
          <volume>23</volume>
          <fpage>29474095</fpage>
          <pub-id pub-id-type="doi">10.1089/acm.2017.0203</pub-id>
          <pub-id pub-id-type="pmid">29474095</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842101452">
        <label>60.</label>
        <mixed-citation xlink:type="simple" publication-type="book"><name><surname>Federman</surname><given-names>A</given-names></name><name><surname>Sarzynski</surname><given-names>E</given-names></name><name><surname>Brach</surname><given-names>C</given-names></name><name><surname>Francaviglia</surname><given-names>P</given-names></name><article-title>Challenges optimizing the after visit summary.Int J Med Inform</article-title><date><year>2018</year></date><chapter-title>Dec;120: 14-19. doi: 10.1016/j.ijmedinf.2018.09.009. Epub</chapter-title>
PMID: 30409339 PMCID:



<pub-id pub-id-type="doi">10.1016/j.ijmedinf.2018.09.009</pub-id><pub-id pub-id-type="pmid">30409339</pub-id></mixed-citation>
      </ref>
      <ref id="ridm1842025716">
        <label>61.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Carter</surname>
            <given-names>Z A</given-names>
          </name>
          <name>
            <surname>Goldman</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Anderson</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Li</surname>
            <given-names>X</given-names>
          </name>
          <article-title>Creation of an Internal Teledermatology Store-and-Forward System in an Existing Electronic Health Record: A Pilot Study in a Safety-Net Public Health and Hospital System.JAMA Dermatol</article-title>
          <date>
            <year>2017</year>
          </date>
          <volume>153</volume>
          <issue>7</issue>
          <fpage>644</fpage>
          <lpage>650</lpage>
          <pub-id pub-id-type="doi">10.1001/jamadermatol.2017.0204</pub-id>
          <pub-id pub-id-type="pmid">28423156</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842022116">
        <label>62.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Milinovich</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Kattan</surname>
            <given-names>M W</given-names>
          </name>
          <article-title>Extracting and utilizing electronic health data from Epic for research.AnnTranslMed</article-title>
          <date>
            <year>2018</year>
          </date>
          <chapter-title>10.21037/atm.2018.01.13 PMCID: PMC5879514 PMID:</chapter-title>
          <volume>6</volume>
          <issue>3</issue>
          <fpage>29610734</fpage>
          <lpage>5879514</lpage>
          <pub-id pub-id-type="doi">10.21037/atm.2018.01.13</pub-id>
          <pub-id pub-id-type="pmid">29610734https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879514/pdf/atm-06-03-42.pdf</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842016644">
        <label>63.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Helmers</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Doebbeling</surname>
            <given-names>B N</given-names>
          </name>
          <name>
            <surname>Kaufman</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Grando</surname>
            <given-names>A</given-names>
          </name>
          <article-title>Mayo Clinic Registry of Operational Tasks (ROOT): A Paradigm Shift in Electronic Health Reco Implementation Evaluation.Mayo Clin ProcInnovQual Outcomes</article-title>
          <date>
            <year>2019</year>
          </date>
          <volume>3</volume>
          <issue>3</issue>
          <fpage>319</fpage>
          <lpage>326</lpage>
          <pub-id pub-id-type="doi">10.1016/j.mayocpiqo.2019.06.004</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842011964">
        <label>64.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Bernstein</surname>
            <given-names>S L</given-names>
          </name>
          <name>
            <surname>Rosner</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>DeWitt</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Tetrault</surname>
            <given-names>J</given-names>
          </name>
          <article-title>Design and implementation of decision support for tobacco dependence treatment in an inpatient electronic medical record: a randomized trial.TranslBehavMed</article-title>
          <date>
            <year>2017</year>
          </date>
          <volume>7</volume>
          <issue>2</issue>
          <fpage>185</fpage>
          <lpage>195</lpage>
          <pub-id pub-id-type="doi">10.1007/s13142-017-0470-8</pub-id>
          <pub-id pub-id-type="pmid">28194729</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842009156">
        <label>65.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>McDowell</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Wu</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Ehrenfeld</surname>
            <given-names>J M</given-names>
          </name>
          <name>
            <surname>Urman</surname>
            <given-names>R D</given-names>
          </name>
          <article-title>Effect of the Implementation of a New Electronic Health Record</article-title>
          <date>
            <year>2017</year>
          </date>
          <chapter-title>System on Surgical Case Turnover Time.J Med Syst. 2017 Mar;41(3): 42</chapter-title>
          <volume>27</volume>
          <fpage>10</fpage>
          <lpage>1007</lpage>
          <pub-id pub-id-type="doi">10.1007/s10916-017-0690-y</pub-id>
          <pub-id pub-id-type="pmid">28130725.https://dx.doi.org/10.1007/s10916-017-0690-y</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1842005124">
        <label>66.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
https://www.epic.com/CareEverywhere/



</mixed-citation>
      </ref>
      <ref id="ridm1842003972">
        <label>67.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Schleelein</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Vincent</surname>
            <given-names>A M</given-names>
          </name>
          <name>
            <surname>Jawad</surname>
            <given-names>A F</given-names>
          </name>
          <name>
            <surname>Pruitt</surname>
            <given-names>E Y</given-names>
          </name>
          <article-title>Pediatric perioperative adverse events requiring rapid response: a retrospective case-control study.PaediatrAnaesth</article-title>
          <date>
            <year>2016</year>
          </date>
          <chapter-title>Jul;26(7): 734-41. doi: 10.1111/pan.12922. Epub</chapter-title>
          <pub-id pub-id-type="doi">10.1111/pan.12922</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841998212">
        <label>68.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Onuha</surname>
            <given-names>O G</given-names>
          </name>
          <name>
            <surname>Hatch</surname>
            <given-names>M B</given-names>
          </name>
          <name>
            <surname>Miano</surname>
            <given-names>T A</given-names>
          </name>
          <name>
            <surname>Fleisher</surname>
            <given-names>L A</given-names>
          </name>
          <article-title>The incidence of un-indicated preoperative testing in a tertiary academic ambulatory center: a retrospective cohort study.PerioperMed (Lond)</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>15</volume>
          <fpage>10</fpage>
          <lpage>1186</lpage>
          <pub-id pub-id-type="doi">10.1186/s13741-015-0023-y</pub-id>
          <pub-id pub-id-type="pmid">26677410</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841994756">
        <label>69.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Krasnowski</surname><given-names>M D</given-names></name><name><surname>Wilford</surname><given-names>J D</given-names></name><name><surname>Howard</surname><given-names>W</given-names></name><name><surname>Dane</surname><given-names>S K</given-names></name><article-title>Implementation of Epic Beaker Clinical Pathology at an academic medical center.JPatholInform</article-title><date><year>2016</year></date><volume>5</volume><fpage>10</fpage><lpage>4103</lpage>
7: 7. Published online



<pub-id pub-id-type="doi">10.4103/2153-3539.175798</pub-id></mixed-citation>
      </ref>
      <ref id="ridm1841990076">
        <label>70.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Langsjoen</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Goodell</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Castro</surname>
            <given-names>E</given-names>
          </name>
          <name>
            <surname>Thomas</surname>
            <given-names>J</given-names>
          </name>
          <article-title>Improving compliance with cervical cancer screening guidelines.Proc (BaylUniv Med Cent)</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>28</volume>
          <issue>4</issue>
          <fpage>450</fpage>
          <lpage>3</lpage>
          <pub-id pub-id-type="pmid">26424938</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841985324">
        <label>71.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Unni</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Yao</surname>
            <given-names>Y</given-names>
          </name>
          <name>
            <surname>Milne</surname>
            <given-names>N</given-names>
          </name>
          <name>
            <surname>Gunning</surname>
            <given-names>K</given-names>
          </name>
          <article-title>An evaluation of clinical risk factors for estimating fracture risk in postmenopausal osteoporosis using an electronic medical record database.OsteoporosInt</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>26</volume>
          <issue>2</issue>
          <fpage>581</fpage>
          <lpage>7</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841982444">
        <label>72.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Hayek</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Nieva</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Corrigan</surname>
            <given-names>F</given-names>
          </name>
          <name>
            <surname>Zhou</surname>
            <given-names>A</given-names>
          </name>
          <article-title>End-of-life care planning: improving documentation of advance directives in the outpatient clinic using electronic medical records.JPalliatMed</article-title>
          <date>
            <year>2014</year>
          </date>
          <chapter-title>Dec;17(12): 1348-52. doi: 10.1089/jpm.2013.0684. PMID:</chapter-title>
          <fpage>24988497</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.1089/jpm.2013.0684</pub-id>
          <pub-id pub-id-type="pmid">24988497</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841976396">
        <label>73.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Bloomfield</surname>
            <given-names>RA Jr</given-names>
          </name>
          <name>
            <surname>Polo-Wood</surname>
            <given-names>F</given-names>
          </name>
          <name>
            <surname>Mandel</surname>
            <given-names>J C</given-names>
          </name>
          <name>
            <surname>Mandl</surname>
            <given-names>K D</given-names>
          </name>
          <article-title>Opening the Duke electronic health record to apps: Implementing</article-title>
          <date>
            <year>2016</year>
          </date>
          <chapter-title>SMART on FHIR.Int J Med Inform. 2017 Mar;99: 1-10. doi: 10.1016/j.ijmedinf.2016.12.005. Epub</chapter-title>
          <fpage>28118917</fpage>
          <lpage>1386505616302738</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ijmedinf.2016.12.005</pub-id>
          <pub-id pub-id-type="pmid">28118917https://www.sciencedirect.com/science/article/abs/pii/S1386505616302738?via%3Dihub</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841971644">
        <label>74.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Moreno-Iribas</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Sayon-Orea</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Delfrade</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Ardanaz</surname>
            <given-names>E</given-names>
          </name>
          <article-title>Validity of type 2 diabetes diagnosis in a population-based electronic health record database.BMC Med InformDecisMak</article-title>
          <date>
            <year>2017</year>
          </date>
          <volume>17</volume>
          <issue>1</issue>
          <fpage>10</fpage>
          <lpage>1186</lpage>
          <pub-id pub-id-type="doi">10.1186/s12911-017-0439-z</pub-id>
          <pub-id pub-id-type="pmid">28390396</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841908908">
        <label>75.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Bush</surname>
            <given-names>R A</given-names>
          </name>
          <name>
            <surname>Connelly</surname>
            <given-names>C D</given-names>
          </name>
          <name>
            <surname>Pérez</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Barlow</surname>
            <given-names>H</given-names>
          </name>
          <article-title>Extracting autism spectrum disorder data from the electronic health record.Appl Clin Inform</article-title>
          <date>
            <year>2017</year>
          </date>
          <volume>8</volume>
          <issue>3</issue>
          <fpage>731</fpage>
          <lpage>741</lpage>
          <pub-id pub-id-type="doi">10.4338/ACI-2017-02-RA-0029</pub-id>
          <pub-id pub-id-type="pmid">28925416</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841904732">
        <label>76.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Wang</surname>
            <given-names>J K</given-names>
          </name>
          <name>
            <surname>Ouyang</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Hom</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Chi</surname>
            <given-names>J</given-names>
          </name>
          <article-title>Characterizing electronic health record usage patterns of inpatient medicine residents using event log data.PLoSOne</article-title>
          <date>
            <year>2019</year>
          </date>
          <fpage>30726208</fpage>
          <pub-id pub-id-type="doi">10.1371/journal.pone.0205379</pub-id>
          <pub-id pub-id-type="pmid">30726208</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841899116">
        <label>77.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Barclay</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Viswanathan</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Ratner</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Tompkins</surname>
            <given-names>J</given-names>
          </name>
          <article-title>Implementing Evidence-Based Screening and Counseling for Unhealthy Alcohol Use with Epic-Based Electronic Health Record Tools.J Comm J Qual PatientSaf</article-title>
          <date>
            <year>2019</year>
          </date>
          <volume>45</volume>
          <issue>8</issue>
          <fpage>566</fpage>
          <lpage>574</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jcjq.2019.05.009</pub-id>
          <pub-id pub-id-type="pmid">31378277</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841894940">
        <label>78.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Gori</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>Banerjee</surname>
            <given-names>I</given-names>
          </name>
          <name>
            <surname>Chung</surname>
            <given-names>B I</given-names>
          </name>
          <name>
            <surname>Ferrari</surname>
            <given-names>M</given-names>
          </name>
          <article-title>Extracting Patient-Centered Outcomes from Clinical Notes in Electronic Health Records: Assessment of Urinary Incontinence After Radical Prostatectomy</article-title>
        </mixed-citation>
      </ref>
      <ref id="ridm1841892780">
        <label>79.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Del</surname>
            <given-names>Fiol G</given-names>
          </name>
          <name>
            <surname>Kohlmann</surname>
            <given-names>W</given-names>
          </name>
          <name>
            <surname>Bradshaw</surname>
            <given-names>R L</given-names>
          </name>
          <name>
            <surname>Weir</surname>
            <given-names>C R</given-names>
          </name>
          <article-title>Standards-Based Clinical Decision Support Platform to Manage Patients Who Meet Guideline-Based Criteria for Genetic Evaluation of Familial Cancer.JCO Clin Cancer Inform</article-title>
          <date>
            <year>2020</year>
          </date>
          <chapter-title>Jan;4: 1-9. doi: 10.1200/CCI.19.00120. PMID:</chapter-title>
          <fpage>31951474</fpage>
          <pub-id pub-id-type="doi">10.1200/CCI.19.00120</pub-id>
          <pub-id pub-id-type="pmid">31951474</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841885940">
        <label>80.</label>
        <mixed-citation xlink:type="simple" publication-type="journal"><name><surname>Bain</surname><given-names>P A</given-names></name><article-title>Collaboration saves time.WMJ:</article-title><date><year>2008</year></date><volume>107</volume><issue>8</issue><fpage>380</fpage><lpage>1</lpage>
PMID: 19331008https://www.wismed.org/wisconsin


<pub-id pub-id-type="pmid">19331008https://www.wismed.org/wisconsin</pub-id></mixed-citation>
      </ref>
      <ref id="ridm1841883852">
        <label>81.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Heidemann</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Law</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Fontana</surname>
            <given-names>R J</given-names>
          </name>
          <article-title>A text searching tool to identify patients with idiosyncratic drug-induced liver Injury.Dig Dis Sci</article-title>
          <date>
            <year>2017</year>
          </date>
          <volume>62</volume>
          <issue>3</issue>
          <fpage>615</fpage>
          <lpage>625</lpage>
          <pub-id pub-id-type="doi">10.1007/s10620-015-3970-8</pub-id>
          <pub-id pub-id-type="pmid">26597192</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841879892">
        <label>82.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Sweet</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Gordon</surname>
            <given-names>E S</given-names>
          </name>
          <name>
            <surname>Sturm</surname>
            <given-names>A C</given-names>
          </name>
          <name>
            <surname>Schmidlen</surname>
            <given-names>T</given-names>
          </name>
          <article-title>Design and implementation of a randomized controlled trial of genomic counseling for patients with chronic disease.J Pers Med</article-title>
          <date>
            <year>2014</year>
          </date>
          <volume>4</volume>
          <issue>1</issue>
          <fpage>1</fpage>
          <lpage>19</lpage>
          <pub-id pub-id-type="doi">10.3390/jpm4010001</pub-id>
          <pub-id pub-id-type="pmid">26597192</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841872620">
        <label>83.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Cox</surname>
            <given-names>M L</given-names>
          </name>
          <name>
            <surname>Farjat</surname>
            <given-names>A E</given-names>
          </name>
          <name>
            <surname>Risoli</surname>
            <given-names>T J</given-names>
          </name>
          <name>
            <surname>Peskoe</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Documenting or Operating: Where Is Time Spent</article-title>
          <chapter-title>in General Surgery Residency?J Surg Educ.2018 Nov;75(6):e97-e106</chapter-title>
          <fpage>10</fpage>
          <lpage>1016</lpage>
          <pub-id pub-id-type="doi">10.1016/j.jsurg.2018.10.010</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841868588">
        <label>84.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Flatow</surname>
            <given-names>V H</given-names>
          </name>
          <name>
            <surname>Ibragimova</surname>
            <given-names>N</given-names>
          </name>
          <name>
            <surname>Divino</surname>
            <given-names>C M</given-names>
          </name>
          <name>
            <surname>Eshak</surname>
            <given-names>D S</given-names>
          </name>
          <article-title>Quality outcomes in the surgical intensive care unit after electronic health record implementation.Appl Clin Inform:</article-title>
          <date>
            <year>2015</year>
          </date>
          <volume>6</volume>
          <issue>4</issue>
          <fpage>611</fpage>
          <lpage>18</lpage>
          <pub-id pub-id-type="pmid">26767058</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841866068">
        <label>85.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Huang</surname>
            <given-names>X G</given-names>
          </name>
          <name>
            <surname>Wong</surname>
            <given-names>Y S</given-names>
          </name>
          <name>
            <surname>Wang</surname>
            <given-names>J G</given-names>
          </name>
          <article-title>A two-stage manufacturing partner selection framework for virtual enterprise.Int</article-title>
          <source>J Comp Int Man</source>
          <volume>16</volume>
          <fpage>153</fpage>
          <lpage>64</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841861316">
        <label>86.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Basel</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Knott</surname>
            <given-names>D</given-names>
          </name>
          <name>
            <surname>S</surname>
            <given-names>van Kuiken</given-names>
          </name>
          <article-title>The big-data revolution in US healthcare: Accelerating value and innovation:</article-title>
          <date>
            <year>2013</year>
          </date>
          <source>McKinsey &amp; Company.April</source>
          <volume>13</volume>
        </mixed-citation>
      </ref>
      <ref id="ridm1841858148">
        <label>87.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kock</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Gemundsen</surname>
            <given-names>H G</given-names>
          </name>
          <article-title>Antecedents to decision-making quality and agility in innovation portfolio management.J ProdInnovMan</article-title>
          <date>
            <year>2016</year>
          </date>
          <volume>33</volume>
          <issue>6</issue>
          <fpage>670</fpage>
          <lpage>686</lpage>
          <pub-id pub-id-type="doi">10111/jpim.12336</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841854188">
        <label>88.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Cleven</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Mettler</surname>
            <given-names>T</given-names>
          </name>
          <name>
            <surname>Rohner</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Winter</surname>
            <given-names>R</given-names>
          </name>
          <article-title>Healthcare quality innovation and performance through process orientation: Evidence from general hospitals in Switzerland.Tech Forecast</article-title>
          <date>
            <year>2016</year>
          </date>
          <source>Soc Change:</source>
          <volume>113</volume>
          <fpage>386</fpage>
          <lpage>395</lpage>
          <publisher-name>DOI:</publisher-name>
        </mixed-citation>
      </ref>
      <ref id="ridm1841849364">
        <label>89.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Chi</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Kugler</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Chu</surname>
            <given-names>I M</given-names>
          </name>
          <name>
            <surname>Loftus</surname>
            <given-names>P D</given-names>
          </name>
          <article-title>Medical students and the electronic health record: 'an epic use of time'.Am</article-title>
          <date>
            <year>2014</year>
          </date>
          <chapter-title>Sep;127(9): 891-5. doi: 10.1016/j.amjmed.2014.05.027. Epub</chapter-title>
          <pub-id pub-id-type="doi">10.1016/j.amjmed.2014.05.027</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841845476">
        <label>90.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Hammoud</surname>
            <given-names>M M</given-names>
          </name>
          <name>
            <surname>Margo</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Christner</surname>
            <given-names>J G</given-names>
          </name>
          <name>
            <surname>Fisher</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Fischer</surname>
            <given-names>S H</given-names>
          </name>
          <article-title>Opportunities and challenges in integrating electronic health records into undergraduate medical education: a national survey of clerkship directors.Teach Learn Med</article-title>
          <volume>24</volume>
          <issue>3</issue>
          <fpage>219</fpage>
          <lpage>24</lpage>
          <pub-id pub-id-type="doi">10.1080/10401334.2012.692267</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841770860">
        <label>91.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Klehr</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Hafner</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Spelz</surname>
            <given-names>L M</given-names>
          </name>
          <name>
            <surname>Steen</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Implementation of standardized nomenclature in the electronic medical record.Int JNursTerminolClassif:</article-title>
          <date>
            <year>2009</year>
          </date>
          <volume>20</volume>
          <issue>4</issue>
          <fpage>169</fpage>
          <lpage>80</lpage>
          <pub-id pub-id-type="doi">10.1111/j.1744-618X.2009.01132.x</pub-id>
          <pub-id pub-id-type="pmid">19883454</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841769132">
        <label>92.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Cheriff</surname>
            <given-names>A D</given-names>
          </name>
          <name>
            <surname>Kapur</surname>
            <given-names>A G</given-names>
          </name>
          <name>
            <surname>Qiu</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Cole</surname>
            <given-names>C L</given-names>
          </name>
          <article-title>Physician productivity and the ambulatory EHR in a large academic multi-specialty physician group.Int J Med Inform</article-title>
          <date>
            <year>2010</year>
          </date>
          <volume>79</volume>
          <issue>7</issue>
          <fpage>492</fpage>
          <lpage>500</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ijmedinf.2010.04.006</pub-id>
          <pub-id pub-id-type="pmid">20478738</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841764092">
        <label>93.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Seltzer</surname>
            <given-names>A Ramirez-Zohfeld</given-names>
          </name>
          <name>
            <surname>Xiong</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Morse</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Lindquist</surname>
            <given-names>L A</given-names>
          </name>
          <article-title>Use of Electronic Health Records by Older Adults, 85 and Older, and Their Caregivers.J AmGeriatrSoc</article-title>
          <date>
            <year>2020</year>
          </date>
        </mixed-citation>
      </ref>
      <ref id="ridm1841760564">
        <label>94.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>C</surname>
            <given-names/>
          </name>
          <name>
            <surname>Chokshi</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Mann</surname>
            <given-names>D</given-names>
          </name>
          <article-title>Wearable Health Technology and Electronic Health Record Integration: Scoping Review and Future Directions.JMIRMhealthUhealth</article-title>
          <date>
            <year>2019</year>
          </date>
          <volume>7</volume>
          <issue>9</issue>
          <fpage>10</fpage>
          <lpage>2196</lpage>
          <pub-id pub-id-type="doi">10.2196/12861</pub-id>
          <pub-id pub-id-type="pmid">31512582</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841755884">
        <label>95.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kim</surname>
            <given-names>G E</given-names>
          </name>
          <name>
            <surname>Afanasiev</surname>
            <given-names>O K</given-names>
          </name>
          <name>
            <surname>O'Dell</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Sharp</surname>
            <given-names>C</given-names>
          </name>
          <article-title>Implementation and evaluation of Stanford Health Care store-and-forward teledermatology consultation workflow built within an existing electronic health record system.JTelemedTelecare</article-title>
          <date>
            <year>2018</year>
          </date>
          <pub-id pub-id-type="doi">10.1177/1357633X18799805</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841753652">
        <label>96.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Calvitti</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Hochheiser</surname>
            <given-names>H</given-names>
          </name>
          <name>
            <surname>Ashfaq</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Bell</surname>
            <given-names>K</given-names>
          </name>
          <article-title>Physician activity during outpatient visits and subjective workload.J Biomed Inform</article-title>
          <date>
            <year>2017</year>
          </date>
          <chapter-title>May;69: 135-149. doi: 10.1016/j.jbi.2017.03.011. Epub</chapter-title>
          <pub-id pub-id-type="doi">10.1016/j.jbi.2017.03.011</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841748036">
        <label>97.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Ratwani</surname>
            <given-names>R M</given-names>
          </name>
          <name>
            <surname>Savage</surname>
            <given-names>E</given-names>
          </name>
          <name>
            <surname>Will</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Arnold</surname>
            <given-names>R</given-names>
          </name>
          <article-title>A usability and safety analysis of electronic health records: a multi-center study.J Am Med Inform Assoc</article-title>
          <date>
            <year>2018</year>
          </date>
          <volume>25</volume>
          <issue>9</issue>
          <fpage>1197</fpage>
          <lpage>1201</lpage>
          <pub-id pub-id-type="doi">10.1093/jamia/ocy088</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841743068">
        <label>98.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Buery-Joyner</surname>
            <given-names>S D</given-names>
          </name>
          <name>
            <surname>Dalrymple</surname>
            <given-names>J L</given-names>
          </name>
          <name>
            <surname>Abbott</surname>
            <given-names>J F</given-names>
          </name>
          <name>
            <surname>Craig</surname>
            <given-names>L B</given-names>
          </name>
          <chapter-title>Overcoming Electronic Medical Record Challenges on the Obstetrics and Gynecology Clerkship.ObstetGynecol: 2015 Sep;126(3):</chapter-title>
          <fpage>553</fpage>
          <lpage>8</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841741124">
        <label>99.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Khairat</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Coleman</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Ottmar</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Bice</surname>
            <given-names>T</given-names>
          </name>
          <article-title>Physicians' gender and their use of electronic health records: findings from a mixed-methods usability study.J Am Med Inform Assoc</article-title>
          <date>
            <year>2019</year>
          </date>
          <volume>26</volume>
          <issue>12</issue>
          <fpage>1505</fpage>
          <lpage>1514</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841736156">
        <label>100.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Whalen</surname>
            <given-names>K</given-names>
          </name>
          <name>
            <surname>Lynch</surname>
            <given-names>E</given-names>
          </name>
          <name>
            <surname>Moawad</surname>
            <given-names>I</given-names>
          </name>
          <name>
            <surname>John</surname>
            <given-names>T</given-names>
          </name>
          <name>
            <surname>al</surname>
            <given-names>eta</given-names>
          </name>
          <article-title>Transition to a new electronic health record and pediatric medication safety: lessons learned in pediatrics within a large academic health system.J Am Med Inform Assoc</article-title>
          <date>
            <year>2018</year>
          </date>
          <volume>25</volume>
          <issue>7</issue>
          <fpage>848</fpage>
          <lpage>854</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841732196">
        <label>101.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Rizvi</surname>
            <given-names>R F</given-names>
          </name>
          <name>
            <surname>Marquard</surname>
            <given-names>J L</given-names>
          </name>
          <name>
            <surname>Seywerd</surname>
            <given-names>M A</given-names>
          </name>
          <name>
            <surname>Adam</surname>
            <given-names>T J</given-names>
          </name>
          <article-title>Usability Evaluation of an EHR's Clinical Notes Interface from the Perspective of Attending and Resident Physicians: An Exploratory Study.Stud Health Technol Inform</article-title>
          <volume>2017</volume>
          <fpage>1128</fpage>
          <lpage>1132</lpage>
          <pub-id pub-id-type="pmid">29688461</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841727804">
        <label>102.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kamil</surname>
            <given-names>R J</given-names>
          </name>
          <name>
            <surname>Giddings</surname>
            <given-names>N</given-names>
          </name>
          <name>
            <surname>Hoffer</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Ying</surname>
            <given-names>Y M</given-names>
          </name>
          <article-title>Electronic Health Record Use Among American Neurotology Society Members.OtolNeurotol</article-title>
          <date>
            <year>2018</year>
          </date>
          <fpage>39</fpage>
          <lpage>9</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841724348">
        <label>103.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Friend</surname>
            <given-names>T H</given-names>
          </name>
          <name>
            <surname>Jennings</surname>
            <given-names>S J</given-names>
          </name>
          <name>
            <surname>Levine</surname>
            <given-names>W C</given-names>
          </name>
          <article-title>Communication Patterns in the Perioperative Environment During Epic Electronic Health Record System Implementation.J Med Syst</article-title>
          <date>
            <year>2017</year>
          </date>
          <chapter-title>Feb;41(2): 22</chapter-title>
          <fpage>10</fpage>
          <lpage>1007</lpage>
          <pub-id pub-id-type="doi">10.1007/s10916-016-0674-3</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841721108">
        <label>104.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Arndt</surname>
            <given-names>B G</given-names>
          </name>
          <name>
            <surname>Beasley</surname>
            <given-names>J W</given-names>
          </name>
          <name>
            <surname>Watkinson</surname>
            <given-names>M D</given-names>
          </name>
          <name>
            <surname>Temte</surname>
            <given-names>J L</given-names>
          </name>
          <article-title>Tethered to the EHR: Primary Care Physician Workload Assessment Using EHR Event Log Data and Time-Motion ObservationsAnn Fam Med2017;</article-title>
          <date>
            <year>1370</year>
          </date>
          <volume>15</volume>
          <fpage>419</fpage>
          <lpage>426</lpage>
          <pub-id pub-id-type="doi">10.1370/afm.2121</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841781804">
        <label>105.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Pereira</surname>
            <given-names>A G</given-names>
          </name>
          <name>
            <surname>Kim</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Seywerd</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Nesbitt</surname>
            <given-names>B</given-names>
          </name>
          <article-title>on behalf of the Minnesota Epic101 Collaborative. Collaborating for Competency-A Model for Single Electronic Health Record Onboarding for Medical Students Rotating among Separate Health Systems.Appl Clin Inform</article-title>
          <date>
            <year>2018</year>
          </date>
          <volume>9</volume>
          <issue>1</issue>
          <fpage>199</fpage>
          <lpage>204</lpage>
          <pub-id pub-id-type="doi">10.1055/s-0038-1635096</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841044316">
        <label>106.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Sharpless</surname>
            <given-names>B R</given-names>
          </name>
          <name>
            <surname>del</surname>
            <given-names>Rosario F</given-names>
          </name>
          <name>
            <surname>Molle-Rios</surname>
            <given-names>Z</given-names>
          </name>
          <name>
            <surname>Hilmas</surname>
            <given-names>E</given-names>
          </name>
          <article-title>Use of Electronic Health Record Tools to Facilitate and Audit Infliximab Prescribing.JPediatrPharmacolTher</article-title>
          <date>
            <year>2018</year>
          </date>
          <volume>23</volume>
          <issue>1</issue>
          <fpage>18</fpage>
          <lpage>25</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841039852">
        <label>107.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Ter-Minassian</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Lanzkron</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Derus</surname>
            <given-names>A</given-names>
          </name>
          <name>
            <surname>Brown</surname>
            <given-names>E</given-names>
          </name>
          <article-title>Quality Metrics and Health Care Utilization for Adult Patients with Sickle Cell Disease.J Natl Med Assoc</article-title>
          <date>
            <year>2019</year>
          </date>
          <chapter-title>Feb;111(1): 54-61. doi: 10.1016/j.jnma.2018.05.003. Epub</chapter-title>
          <fpage>30129484</fpage>
          <pub-id pub-id-type="doi">10.1016/j.jnma.2018.05.003</pub-id>
          <pub-id pub-id-type="pmid">30129484</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841035532">
        <label>108.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Palestine</surname>
            <given-names>A G</given-names>
          </name>
          <name>
            <surname>Merrill</surname>
            <given-names>P T</given-names>
          </name>
          <name>
            <surname>Saleem</surname>
            <given-names>S M</given-names>
          </name>
          <name>
            <surname>Jabs</surname>
            <given-names>D A</given-names>
          </name>
          <name>
            <surname>Thorne</surname>
            <given-names>J E</given-names>
          </name>
          <date>
            <year>2018</year>
          </date>
          <chapter-title>Assessing the Precision of ICD-10 Codes for Uveitis in 2 Electronic Health Record Systems.JAMAOphthalmol</chapter-title>
          <volume>136</volume>
          <issue>10</issue>
          <fpage>1186</fpage>
          <lpage>1190</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841032508">
        <label>109.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Holmgren</surname>
            <given-names>A J</given-names>
          </name>
          <name>
            <surname>Adler-Milstein</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>McCulloughJ</surname>
            <given-names/>
          </name>
          <article-title>Are all certified EHRs created equal? Assessing the relationship between EHR vendor and hospital meaningful use performance.J Am Med Inform Assoc</article-title>
          <date>
            <year>2018</year>
          </date>
          <volume>25</volume>
          <issue>6</issue>
          <fpage>654</fpage>
          <lpage>660</lpage>
          <pub-id pub-id-type="doi">10.1093/jamia/ocx135</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841026676">
        <label>110.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Boland</surname>
            <given-names>M V</given-names>
          </name>
          <name>
            <surname>Hwang</surname>
            <given-names>T S</given-names>
          </name>
          <name>
            <surname>Lim</surname>
            <given-names>M C</given-names>
          </name>
          <name>
            <surname>Peterson</surname>
            <given-names>J L</given-names>
          </name>
          <article-title>Medicare Incentive Payments to United States Ophthalmologists for Use of Electronic Health Records: 2011-2016.Ophth:</article-title>
          <date>
            <year>2019</year>
          </date>
          <volume>126</volume>
          <issue>7</issue>
          <fpage>928</fpage>
          <lpage>934</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841022284">
        <label>111.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Goldberg</surname>
            <given-names>H S</given-names>
          </name>
          <name>
            <surname>Paterno</surname>
            <given-names>M D</given-names>
          </name>
          <name>
            <surname>Grundmeier</surname>
            <given-names>R W</given-names>
          </name>
          <name>
            <surname>Rocha</surname>
            <given-names>B H</given-names>
          </name>
          <article-title>Use of a remote clinical decision support service for a multicenter trial to implement prediction rules for children with minor blunt head trauma.Int J Med Inform</article-title>
          <date>
            <year>2016</year>
          </date>
          <chapter-title>Mar;87:</chapter-title>
          <fpage>101</fpage>
          <lpage>10</lpage>
          <pub-id pub-id-type="doi">10.1016/j.ijmedinf.2015.12.002</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841020700">
        <label>112.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Kullar</surname>
            <given-names>R</given-names>
          </name>
          <name>
            <surname>Goff</surname>
            <given-names>D A</given-names>
          </name>
          <name>
            <surname>Schulz</surname>
            <given-names>L T</given-names>
          </name>
          <name>
            <surname>Fox</surname>
            <given-names>B C</given-names>
          </name>
          <article-title>The "epic" challenge of optimizing antimicrobial stewardship: the role of electronic medical records and technology.Clin Infect Dis:</article-title>
          <date>
            <year>2013</year>
          </date>
          <volume>57</volume>
          <issue>7</issue>
          <fpage>1005</fpage>
          <lpage>13</lpage>
          <pub-id pub-id-type="doi">10.1093/cid/cit318</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841014508">
        <label>113.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Steidl</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Zimmern</surname>
            <given-names>P</given-names>
          </name>
          <article-title>Data for free--can an electronic medical record provide outcome data for incontinence/prolapse repair procedures?J Urol</article-title>
          <date>
            <year>2013</year>
          </date>
          <fpage>10</fpage>
          <lpage>1016</lpage>
          <pub-id pub-id-type="doi">10.1016/j.juro.2012.08.186</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841011988">
        <label>114.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Chima</surname>
            <given-names>C S</given-names>
          </name>
          <name>
            <surname>Farmer-Dziak</surname>
            <given-names>N</given-names>
          </name>
          <name>
            <surname>Cardwell</surname>
            <given-names>P</given-names>
          </name>
          <name>
            <surname>Snow</surname>
            <given-names>S</given-names>
          </name>
          <article-title>Use of technology to track program outcomes in a diabetes self-management program.J Am Diet Assoc:</article-title>
          <date>
            <year>2005</year>
          </date>
          <volume>105</volume>
          <issue>12</issue>
          <fpage>1933</fpage>
          <lpage>8</lpage>
        </mixed-citation>
      </ref>
      <ref id="ridm1841009540">
        <label>115.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Adelson</surname>
            <given-names>K B</given-names>
          </name>
          <name>
            <surname>Qiu</surname>
            <given-names>Y C</given-names>
          </name>
          <name>
            <surname>Evangelista</surname>
            <given-names>M</given-names>
          </name>
          <name>
            <surname>Spencer-Cisek</surname>
            <given-names>P</given-names>
          </name>
          <article-title>Implementation of electronic chemotherapy ordering: an opportunity to improve evidence-based oncology care.J OncolPract</article-title>
          <date>
            <year>2014</year>
          </date>
          <chapter-title>Mar;10(2):e113-9. doi: 10.1200/JOP.2013.001184. PMID:</chapter-title>
          <fpage>24371301</fpage>
          <pub-id pub-id-type="doi">10.1200/JOP.2013.001184</pub-id>
          <pub-id pub-id-type="pmid">24371301</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841007020">
        <label>116.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Sonstein</surname>
            <given-names>L</given-names>
          </name>
          <name>
            <surname>Clark</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Seidensticker</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Zeng</surname>
            <given-names>L</given-names>
          </name>
          <article-title>Improving adherence for management of acute exacerbation of chronic obstructive pulmonary disease.Am</article-title>
          <date>
            <year>2014</year>
          </date>
          <volume>127</volume>
          <issue>11</issue>
          <fpage>1097</fpage>
          <lpage>104</lpage>
          <pub-id pub-id-type="doi">10.1016/j.amjmed.2014.05.033</pub-id>
          <pub-id pub-id-type="pmid">24927911</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1841000756">
        <label>117.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Brenn</surname>
            <given-names>B R</given-names>
          </name>
          <name>
            <surname>Choudhry</surname>
            <given-names>D K</given-names>
          </name>
          <name>
            <surname>Sacks</surname>
            <given-names>K</given-names>
          </name>
          <article-title>Outpatient outcomes and satisfaction in pediatric population: data from the postoperative phone call.PaediatrAnaesth</article-title>
          <date>
            <year>2016</year>
          </date>
          <volume>26</volume>
          <issue>2</issue>
          <fpage>158</fpage>
          <lpage>63</lpage>
          <pub-id pub-id-type="doi">10.1111/pan.12817</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1840997372">
        <label>118.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Bush</surname>
            <given-names>R A</given-names>
          </name>
          <name>
            <surname>Kuelbs</surname>
            <given-names>C</given-names>
          </name>
          <name>
            <surname>Ryu</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Jiang</surname>
            <given-names>W</given-names>
          </name>
          <date>
            <year>2017</year>
          </date>
          <chapter-title>Structured Data Entry in the Electronic Medical Record: Perspectives of Pediatric Specialty Physicians and Surgeons.J Med Syst. 2017 May;41(5): 75</chapter-title>
          <fpage>10</fpage>
          <lpage>1007</lpage>
          <pub-id pub-id-type="doi">10.1007/s10916-017-0716-5</pub-id>
          <pub-id pub-id-type="pmid">28324321</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1840994276">
        <label>119.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Khoshsima</surname>
            <given-names>G</given-names>
          </name>
          <article-title>A strategic model for measuring agility with fuzzy logic</article-title>
          <date>
            <year>2008</year>
          </date>
          <chapter-title>Advances in Computation and Intelligence.Lecture Notes in Computer Science</chapter-title>
          <volume>5370</volume>
          <fpage>258</fpage>
          <lpage>268</lpage>
          <pub-id pub-id-type="doi">10.1007/978-3-540-92137-0_29</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1840990316">
        <label>120.</label>
        <mixed-citation xlink:type="simple" publication-type="journal">
          <name>
            <surname>Vinodh</surname>
            <given-names>S</given-names>
          </name>
          <name>
            <surname>Sakthivel</surname>
            <given-names>A R</given-names>
          </name>
          <article-title>Agility evaluation using the IF-THEN approach.Int</article-title>
          <date>
            <year/>
          </date>
          <source>J Prod Res:</source>
          <volume>15</volume>
          <fpage>7100</fpage>
          <lpage>7109</lpage>
          <pub-id pub-id-type="doi">0.1080/00207543.2010.524260</pub-id>
        </mixed-citation>
      </ref>
      <ref id="ridm1840988372">
        <label>121.</label>
        <mixed-citation xlink:type="simple" publication-type="book">
          <name>
            <surname>Zavodnick</surname>
            <given-names>J</given-names>
          </name>
          <name>
            <surname>Kouvatsos</surname>
            <given-names>T</given-names>
          </name>
          <date>
            <year>2019</year>
          </date>
          <chapter-title>Electronic Health Record Skills Workshop for Medical Students.MedEdPORTAL:.15</chapter-title>
          <fpage>10</fpage>
          <lpage>15766</lpage>
          <pub-id pub-id-type="doi">10.15766/mep_2374-8265.10849</pub-id>
        </mixed-citation>
      </ref>
    </ref-list>
  </back>
</article>
