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 <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd"> <article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="mini-review" dtd-version="1.0" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">IJGH</journal-id>
      <journal-title-group>
        <journal-title>International Journal of Global Health</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2693-1176</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.14302/issn.2693-1176.ijgh-20-3269</article-id>
      <article-id pub-id-type="publisher-id">IJGH-20-3269</article-id>
      <article-categories>
        <subj-group>
          <subject>mini-review</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>The Hazards of Abdominal Obesity  </article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Seyedeh</surname>
            <given-names>Nasim Habibzadeh</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842613100">1</xref>
          <xref ref-type="aff" rid="idm1842613244">*</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842613100">
        <label>1</label>
        <addr-line>School of Health and Life Since, Teesside University, United Kingdom.</addr-line>
      </aff>
      <aff id="idm1842613244">
        <label>*</label>
        <addr-line>corresponding author</addr-line>
      </aff>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Qianqian</surname>
            <given-names>Song</given-names>
          </name>
          <xref ref-type="aff" rid="idm1842746148">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1842746148">
        <label>1</label>
        <addr-line>Wake Forest School of Medicine, Wake Forest Baptist Comprehensive Cancer Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA</addr-line>
      </aff>
      <author-notes>
        <corresp>Corresponding author: Seyedeh Nasim Habibzadeh, School of Health and Life Science, Teesside University, United Kingdom. Email: <email>nasimhabibzadeh@yahoo.com</email></corresp>
        <fn fn-type="conflict" id="idm1843375828">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2020-04-13">
        <day>13</day>
        <month>04</month>
        <year>2020</year>
      </pub-date>
      <volume>1</volume>
      <issue>1</issue>
      <fpage>11</fpage>
      <lpage>13</lpage>
      <history>
        <date date-type="received">
          <day>13</day>
          <month>03</month>
          <year>2020</year>
        </date>
        <date date-type="accepted">
          <day>10</day>
          <month>04</month>
          <year>2020</year>
        </date>
        <date date-type="online">
          <day>13</day>
          <month>04</month>
          <year>2020</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2020</copyright-year>
        <copyright-holder>Seyedeh Nasim Habibzadeh</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org//ijgh/article/1318">This article is available from http://openaccesspub.org//ijgh/article/1318</self-uri>
      <abstract>
        <p>Abdominal obesitywith a big belly is one of the worse type of morbid obesity that is associated with different health failure outcomes. Central obesity leads to an increased risk of health complications such as metabolic syndrome, hypertension, insulin resistance,type 2 diabetes, heart disease and various cancers. Abdominal obesity also can specifically cause to spinal nerve pain and backache. Depression and disability are other subsequent hazards of central fatness. More importantly ,excessive central body fat ultimately contributes in all-causes of early mortality. In regards to this, individuals with abdominal obesity is urgently needed to reduce central obesity using behavior modifications. Changes in diet and performing some exercise in everyday living are essential steps. </p>
        <p> </p>
      </abstract>
      <kwd-group>
        <kwd>Abdominal fatness</kwd>
        <kwd>Risks</kwd>
        <kwd>Clinical problems</kwd>
        <kwd>Morbidity</kwd>
      </kwd-group>
      <counts>
        <fig-count count="0"/>
        <table-count count="0"/>
        <page-count count="3"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1842473244" sec-type="intro">
      <title>Introduction</title>
      <p>Abdominal or central obesity are characterized with excessive body fat in waist circumference<xref ref-type="bibr" rid="ridm1842180252">1</xref>. The prevalence of visceral fat that accumulates around abdominal organs is increasing worldwide<xref ref-type="bibr" rid="ridm1842181692">2</xref><xref ref-type="bibr" rid="ridm1842187860">3</xref>. Visceral fat cells have an crucial impact on overall health  and  well-being.</p>
      <p>Gene-based association studies suggest a strong correlation between genes and abdominal fat<xref ref-type="bibr" rid="ridm1842286948">4</xref>. Heredity and genetic variants and hormones abnormalities can affect abdominal fat<xref ref-type="bibr" rid="ridm1842036620">5</xref>. </p>
      <p>Inappropriate diets such as  high-calorie foods are other main influential risk factors for increasing abdominal obesity. High-sugar foods such as sweets, cakes, biscuits, pizza and chips can dramatically enhance intra-abdominal fat cells<xref ref-type="bibr" rid="ridm1842035684">6</xref>. Cigarette smoking habits and alcohol intakes also seem to increase central adiposity with an adverse health consequences<xref ref-type="bibr" rid="ridm1842038924">7</xref>. </p>
      <p>Moreover, sedentary life - style such as sitting for long hours (i.e. low physical job demand) develops the abdominal adipose that intensifies central obesity over time. Sedentary individuals burn fewer calories than active individuals per day in terms of daily energy expenditure which leads to the belly fat accumulation in long-terms. Overall central body fat owing to                  prolong inactive life–style pattern can cause sitting diseases<xref ref-type="bibr" rid="ridm1842029836">8</xref>.</p>
      <p>In accordance to this, abdominal adiposity alters normal lipid metabolism at which reduces the                low-density-lipoprotein (LDL) cholesterol (or good cholesterol) levels and raises the high-density lipoprotein (HDL) cholesterol (or bad cholesterol) levels  in body. Abdominal obesity also increases blood sugar, triglycerides that is assumed to be the predominant risk factors for metabolic syndrome<xref ref-type="bibr" rid="ridm1842023500">9</xref>. Indeed , visceral adiposity is closely linked to the insulin resistance, which can lead to the glucose intolerance and type 2 diabetes in obese individuals<xref ref-type="bibr" rid="ridm1842011092">10</xref><xref ref-type="bibr" rid="ridm1842014476">11</xref>. Excessive central body fat has an important role in coronary artery disease such as hypertension                          (high-blood pressure) and atherosclerosis<xref ref-type="bibr" rid="ridm1841987316">12</xref><xref ref-type="bibr" rid="ridm1841984076">13</xref>. Furthermore, central body fatness is a strong predictors for different cancers incidence among obese and overweight populations<xref ref-type="bibr" rid="ridm1841979972">14</xref>. With regards to this, growing evidence shows that prenominal abdominal obesity is associated with an increased risk of lifetime disability and greater reduction in life expectancy in part for male individuals<xref ref-type="bibr" rid="ridm1841977596">15</xref><xref ref-type="bibr" rid="ridm1841990628">16</xref>.</p>
      <p>Therefore, the prevention and treatment of abdominal obesity is urgently required. The key health strategies for preventing and managing the abdominal obesity are minimizing over-eating and increasing physical activity levels in daily life<xref ref-type="bibr" rid="ridm1841972004">17</xref>. In regards to this, behavioural consultation to promote a healthy diet and physical activity account for very useful therapeutic strategy to reduce the abdominal obesity for individual with central obesity.</p>
    </sec>
    <sec id="idm1842471228" sec-type="conclusions">
      <title>Conclusion</title>
      <p>Abdominal obesity (or abdominal adiposity) is increasing worldwide . Visceral fat cells affect the overall health and well-being and is associated with all-causes of morbidity. Genetic , unhealthy diets and an inactive lifestyle are main risk factors of central obesity. In regards to this, behavior modifications such as increasing the physical activity levels and controlling the food intakes using an appropriate healthy diet can be very good approach to prevent and to reduce the visceral obesity over time.</p>
    </sec>
  </body>
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