<?xml version="1.0" encoding="utf8"?>
 <!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.0 20120330//EN" "http://jats.nlm.nih.gov/publishing/1.0/JATS-journalpublishing1.dtd"> <article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.0" xml:lang="en">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JCRHAP</journal-id>
      <journal-title-group>
        <journal-title>Journal of Clinical Research In HIV AIDS And Prevention</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2324-7339</issn>
      <publisher>
        <publisher-name>Open Access Pub</publisher-name>
        <publisher-loc>United States</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">JCRHAP-19-2746</article-id>
      <article-id pub-id-type="doi">10.14302/issn.2324-7339.jcrhap-19-2746</article-id>
      <article-categories>
        <subj-group>
          <subject>research-article</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Prevalence of Hiv Infection Among Pregnant Women Attending Ajiko Medical Clinic, Damaturu, Nigeria</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author">
          <name>
            <surname>Sabina</surname>
            <given-names>Khanam</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843334900">1</xref>
          <xref ref-type="aff" rid="idm1843333892">*</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1843334900">
        <label>1</label>
        <addr-line>Department of Biological Sciences, Yobe State University, Nigeria</addr-line>
      </aff>
      <aff id="idm1843333892">
        <label>*</label>
        <addr-line>corresponding author</addr-line>
      </aff>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Bechan</surname>
            <given-names>Sharma</given-names>
          </name>
          <xref ref-type="aff" rid="idm1843454940">1</xref>
        </contrib>
      </contrib-group>
      <aff id="idm1843454940">
        <label>1</label>
        <addr-line>Professor of Biochemistry &amp; Nodal Officer: Intellectual Property Rights Cell, Chairman: Core Committee-Environmental Science, University of Allahabad, India</addr-line>
      </aff>
      <author-notes>
        <corresp>
    
    Sabina Khanam, <addr-line>Department of Biological Sciences, </addr-line><addr-line>Yobe</addr-line><addr-line> State University, Nigeria</addr-line>,         Email: <email>sabinakhanam@ymail.com</email></corresp>
        <fn fn-type="conflict" id="idm1850781396">
          <p>The authors have declared that no competing interests exist.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub" iso-8601-date="2019-05-13">
        <day>13</day>
        <month>05</month>
        <year>2019</year>
      </pub-date>
      <volume>3</volume>
      <issue>4</issue>
      <fpage>7</fpage>
      <lpage>9</lpage>
      <history>
        <date date-type="received">
          <day>29</day>
          <month>03</month>
          <year>2019</year>
        </date>
        <date date-type="accepted">
          <day>11</day>
          <month>05</month>
          <year>2019</year>
        </date>
        <date date-type="online">
          <day>13</day>
          <month>05</month>
          <year>2019</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© </copyright-statement>
        <copyright-year>2019</copyright-year>
        <copyright-holder>Sabina Khanam</copyright-holder>
        <license xlink:href="http://creativecommons.org/licenses/by/4.0/" xlink:type="simple">
          <license-p>This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.</license-p>
        </license>
      </permissions>
      <self-uri xlink:href="http://openaccesspub.org/jcrhap/article/1082">This article is available from http://openaccesspub.org/jcrhap/article/1082</self-uri>
      <abstract>
        <p>Human immunodeficiency viruses causes HIV infection in humans belongs to two species of Lentivirus. It damages the cells of immune system which leads to weak immune system and the ability to fight from infections and diseases. This study was conducted to investigate the prevalence rate of HIV infection among pregnant women of different age groups attending Ajiko medical clinic, Damaturu, Nigeria. The prevalence rate was maximum (12.5%) in 36-45 age group and minimum (5%) in 26-35 age group but their was no HIV infection in 15-25 age group. The overall prevalence rate among pregnant women was 4%. General knowledge , training and campaigns of HIV prevention need to be tailored towards older women of age group 36-45 because of high prevalence rate.</p>
      </abstract>
      <counts>
        <fig-count count="0"/>
        <table-count count="1"/>
        <page-count count="3"/>
      </counts>
    </article-meta>
  </front>
  <body>
    <sec id="idm1843194692" sec-type="intro">
      <title>Introduction</title>
      <p>Human immunodeficiency virus (HIV) is the major disease spread through certain body fluids that weakens the immune system by destroying the cells such as CD4 cells or T cells of human immune system. It is one of the major health problem worldwide. Around two-third (68%) population of sub-Sahara Africa is affected by  Acquired Immunodeficiency Syndrome (AIDS) which is 12% of the total world’s population. The prevalence rate of HIV infection in Nigeria is around 3.6% which is third largest number of HIV infected people in the world <xref ref-type="bibr" rid="ridm1842316556">1</xref><xref ref-type="bibr" rid="ridm1842170844">6</xref><xref ref-type="bibr" rid="ridm1842152956">7</xref>. </p>
      <p>Around 90% of HIV infection are caused through mother to child infection. In Nigeria nearly sixty thousand children are infected through transmission of HIV by their mother. Paediatric HIV has been virtually wiped out in many developing countries. Large decrease in the number of HIV infection among children was found in Ghana and South Africa from 2009 to 2012. In Nigeria only 58% of pregnant women received antenatal care in 2008 while in 2009 only 22% of HIV positive pregnant women received antiretroviral for the prevention of HIV transmission to her baby and 13% of pregnant women were tested for HIV                                infection <xref ref-type="bibr" rid="ridm1842379140">2</xref><xref ref-type="bibr" rid="ridm1842383100">4</xref><xref ref-type="bibr" rid="ridm1842154684">9</xref><xref ref-type="bibr" rid="ridm1842140452">10</xref></p>
    </sec>
    <sec id="idm1843195268" sec-type="materials">
      <title>Material and Method</title>
      <sec id="idm1843195556">
        <title>Study Area</title>
        <p>The study was carried out in Damaturu, the capital of Yobe State, Nigeria. According to 2006 census the population of Damaturu is 88,100 with 25.2 degree Centigrade average temperature.</p>
      </sec>
      <sec id="idm1843195484">
        <title>Sample Size</title>
        <p>Fifty pregnant women attending Ajiko Medical Clinic, Damaturu were target for the study. Their age and HIV infection were analysed.</p>
      </sec>
      <sec id="idm1843194404">
        <title>HIV Screening</title>
        <p>Women attending  Ajiko Medical Clinic, Damaturu were tested for HIV infection by using ELISA test. Prevalence of HIV infection in them was calculated.</p>
      </sec>
      <sec id="idm1843192316">
        <title>Prevalence Rate</title>
        <sec id="idm1843193180">
          <title>Prevalence Rate was Calculated by Using the Following Formula</title>
          <fig id="idm1849496956">
            <graphic xlink:href="images/image1.jpg" mime-subtype="jpg"/>
          </fig>
        </sec>
      </sec>
    </sec>
    <sec id="idm1843192460" sec-type="results">
      <title>Results and Discussion</title>
      <p>A total of fifty pregnant women were tested for HIV infection of which two women were HIV infected. The prevalence rate was maximum (12.5%) in 36-45 age group and minimum (5%) in 26-35 age group but their was no HIV infection was found in 15-25 age group (<xref ref-type="table" rid="idm1849484196">Table 1</xref>). <xref ref-type="bibr" rid="ridm1842168900">5</xref> reported that 70% of pregnant women were aware of HIV infection and 33% women knew about the main modes of HIV transmission. </p>
      <table-wrap id="idm1849484196">
        <label>Table 1.</label>
        <caption>
          <title> Showing Prevalence of HIV infection among pregnant women of different age groups</title>
        </caption>
        <table rules="all" frame="box">
          <tbody>
            <tr>
              <td>Age Group</td>
              <td>No. of cases (N)</td>
              <td>HIV positive (n)</td>
              <td>Prevalence (%)</td>
            </tr>
            <tr>
              <td>15-25</td>
              <td>22</td>
              <td>0</td>
              <td>0</td>
            </tr>
            <tr>
              <td>26-35</td>
              <td>20</td>
              <td>1</td>
              <td>5</td>
            </tr>
            <tr>
              <td>36-45</td>
              <td>8</td>
              <td>1</td>
              <td>12.5</td>
            </tr>
            <tr>
              <td>Total15-45</td>
              <td>50</td>
              <td>2</td>
              <td>Overall Prevalence Rate4</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <p>Studied 1.03% of seroprevalence of HIV infection among pregnant women attending antenatal clinic in North India which is much higher than other studies<xref ref-type="bibr" rid="ridm1842158572">8</xref>. Some of the researchers revealed that about 73% 0f the health care providers studied that a baby born by the HIV positive mother invariably would be infected <xref ref-type="bibr" rid="ridm1842328988">3</xref>.</p>
    </sec>
    <sec id="idm1843178556" sec-type="conclusions">
      <title>Conclusion</title>
      <p>In this study the overall prevalence rate among pregnant women was 4%. General knowledge , training and campaigns of HIV prevention need to be tailored towards older women of age group 36-45 because of high prevalence rate.</p>
    </sec>
  </body>
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